WPI Blog

Disposable vs. Reusable Forceps: Which is Better?

Surgical forceps are available in several different grades, including disposable, standard stainless steel, German steel, Swiss made, and titanium. Your choice of instrument grade will depend on your requirements and your budget. Here are some considerations to help you make an informed decision.

The Importance of Blood-Brain Barrier Models and Measurement: A Focus on TEER

Choosing a dependable lab equipment supplier is crucial for ensuring the quality, reliability, and timely delivery of the equipment you require.  When your research is on the line, you need a company you trust, a supplier with a proven track record and a service team to back you up. Here are a few important considerations when selecting a lab equipment supplier.

How to Reduce Strain and Discomfort When Using Lab Scissors

Reducing hand fatigue while using surgical scissors is important, not only for your comfort, but also to maintain the precision of your work. Here are some tips to help reduce strain and minimize hand fatigue.

Kelly Clamps vs. Hemostats: What's the Difference?

Surgical forceps are available in several different grades, including disposable, standard stainless steel, German steel, Swiss made, and titanium. Your choice of instrument grade will depend on your requirements and your budget. Here are some considerations to help you make an informed decision.

Forceps Versus Tweezers: What's the Difference?

Surgical forceps and surgical tweezers are handheld surgical instruments for grasping or clamping, but they serve different purposes and have distinct features. While both are used for manipulating small objects, forceps are typically used in medical and research environments, and tweezers have a broader use in hobbies, daily routine tasks, and mechanical applications. Here we will explore some of the differences between the two, including their construction and uses.

Understanding Dumont Surgical Instruments

Dumont is a well-known brand that specializes in the production of high-quality precision forceps and tweezers for surgical and scientific use, as well as for electronics, jewelry, and other  applications. Dumont surgical instruments, particularly Dumont tweezers, are highly regarded for their precision, craftsmanship, and durability.

The Difference Between Metzenbaum and Mayo Scissors

Metzenbaum and Mayo scissors are both types of surgical scissors, and while they may look similar at first glance, they serve different purposes. Let’s look at the differences between the two scissors styles.

8 Tips to Keep Surgical Scissors Sharp

Keeping your fine surgical scissors sharp is paramount for ensuring clean, efficient cuts. The precision of surgical cuts is crucial to the quick recovery of your subject and for minimizing the chance of infections. These tips will help keep your surgical scissors sharp and ensure a longer life for your instruments.

10 Common Reasons Why Syringes Leak and What You Can Do

Leakages of your syringe can be extremely detrimental to the success of your fluid administration and overall application quality. Listed here are seven cases showing why your syringe might experiencing leakage, and how to overcome this.

How Microfluidics is Changing Drug Development

Microfluidics is an ever-expanding practice involving fine-tuned control of ultra-low volumes of fluid, generally within the nanoliter to microliter scale. This area of study has considerably shifted approaches to scientific and industrial discovery. Particularly, utilizing a microfluidics-based approach in the realm of drug development has shown great promise in catalyzing movement to clinical trials by allowing for biological processes to be studied ex vivo, using more relevant human tissue models.  Listed are just some of the means by which microfluidics is improving drug development processes.

Affordable Precision: Why WPI’s Economy Disposable Instruments Belong in Every Lab

When every minute counts in the lab, having clean, ready-to-use instruments can make all the difference. That’s why WPI’s Economy Disposable Instruments line is designed for convenience, affordability, and consistency… so researchers and educators can focus on the work that matters most.

VIDEO: How to Set up a Rat/Mouse Stereotaxic Frame

Let’s take a look at how to set up a Digital Rat/Mouse, Neonatal Rat Stereotaxic frame. In a few steps you will be up and running.

PRESS RELEASE: Introducing World Precision Instruments' Scientific Advisory Board

SARASOTA, Fla., November 10, 2023 /PRNewswire/ -- World Precision Instruments (WPI), a leading provider of high-quality laboratory instruments and equipment for basic research and drug development, is proud to announce the establishment of its Scientific Advisory Board (SAB). Comprised of renowned experts in various scientific disciplines, the SAB will play a crucial role in guiding and advancing WPI's commitment to innovation and excellence in scientific research.

Micromanipulator Basics

Micromanipulators are widely used in cell biology, neurobiology, microelectronics, and microsurgery. Micromanipulators enable researchers to perform intricate tasks with high accuracy and stability, making them indispensable laboratory tools in a variety of applications.

PRESS RELEASE: EVOM Auto with Both 24 & 96 Capability

SARASOTA, Fla., October 23, 2023 /PRNewswire/ -- World Precision Instruments (WPI) is excited to expand the capability of the EVOM™ Auto, now offering both 24 and 96 multiwell capacity in one single platform.  The EVOM™ Auto enables rapid and reproducible measurements of Transepithelial Electrical Resistance (TEER), a well-established, non-invasive and widely accepted method of evaluating epithelial and endothelial cells and tissues. 

How to Troubleshoot TEER Measurement Problems

Transepithelial/transendothelial electrical resistance (TEER) measurement is one of the most used practices to evaluate cellular health, such as cellular confluence, barrier integrity, or barrier function of cellular monolayers grown onto multiwells. The TEER measurement using WPI’s Epithelial Voltohmmeter (EVOM) is considered the gold standard because of its reliable measurements and numerous literature citations using various cell types. The EVOM™ Manual and EVOM™ Auto along with different choices of electrodes (STX4, STX HTS high throughput screening, EndOhm chambers, and multielectrode array for EVOM™ Auto) allow researchers to perform and analyze cell samples in 6, 12, and 24 removable inserts and 24 and 96 HTS multiwell plate formats. The major challenges researchers may encounter while performing studies to capture TEER measurement include:
·      Unstable read outs
·      Out of range values 
·      Inconsistent measurements among sample replicates or batches.
Consider the following factors to overcome any TEER measurement problems and obtain accurate and reliable measurements. 

What are the Benefits of TEER?

Transepithelial Electrical Resistance (TEER) is a widely used technique in the life sciences fields and therapeutic development. It measures the electrical resistance across a cell monolayer, providing information about the integrity and functionality of epithelial barriers. TEER has proven to be a valuable tool in various fields, including drug absorption studies, tissue engineering, and disease modeling. This article aims to explore the benefits of TEER and its applications in different research areas.

Tips for Choosing the Right Pair of Lab Scissors

EVOM™ Auto High Throughput (HTS) Transepithiel Electrical Resistance (TEER) Measurement System with 24 and 96 transwell capability can switch between different 24 and 96 HTS well plates by using matching electrode arrays and plate positioners. Here we demonstrate how to switch to a 24 transwell plate after using a 96 transwell plate. 

VIDEO: How to Set up the EVOM™ Auto Interface Unit & Autosampler

EVOM™ Auto is WPI’s latest high throughput screening TEER measurement system with 24 and 96 HTS transwell plate measurement capability, and it offers easy options for switching between different plates. I will show you how to setup it up. The Interface Unit is the controller that establishes communication between the EVOM™ Auto software and the autosampler. 

VIDEO: How to Install EVOM™ Auto Transwell Plate

EVOM™ Auto High Throughput (HTS) Transepithiel Electrical Resistance (TEER) Measurement System with 24 and 96 transwell capability can switch between different 24 and 96 HTS transwell plates by using matching electrode arrays and plate positioner. Here we demonstrate how to install a well plate. 

VIDEO: How to Remove EVOM™ Auto Electrode Array

The EVOM™ Auto High Throughput (HTS) Transepithiel Electrical Resistance (TEER) Measurement System with 24 and 96 transwell capability has a removable electrode array head. Different electrode arrays can be used with the same system to analyze a variety of 24 and 96 transwell HTS plates. 

VIDEO: How to Switch EVOM Auto Electrode Array

EVOM™ Auto High Throughput (HTS) Transepithiel Electrical Resistance (TEER) Measurement System with 24 and 96 transwell capability can switch between different 24 and 96 HTS well plates by using matching electrode arrays and plate positioners. Here we demonstrate how to switch to a 24 transwell plate after using a 96 transwell plate. 

The Ultimate Guide to Micromanipulators

 Micromanipulators  are an important tool used to execute minute, fine-tuned movements critical for various applications including microinjection into cells or tissue, microscopy, as well as for research involving biological and nano-engineering implementation. Before selecting a micromanipulator, consider the following to choose the best option for your application:

Introduction Hemostatic Forceps & Their Use in Labs

Hemostatic forceps, also called ring forceps or hemostats, are common surgical instruments used in medical, veterinary, and laboratory settings to control bleeding during procedures. Hemostats are used to clamp blood vessels, tissues, or other small structures, effectively minimizing blood flow during surgical procedures. Hemostats prevent excessive bleeding for the subject and offer a clear view of the surgical site for the operator. Here’s a brief introduction to the features and uses of hemostatic forceps in a laboratory setting.