When working with gas-tight NanoFil™ syringes, especially in applications involving viral vectors or delicate biological samples, priming your syringe correctly is essential to ensure reliable and accurate sample delivery. Even microscopic air pockets can lead to inconsistent dosing or air injection, which can be detrimental in high-precision workflows. Here's a step-by-step guide to priming your NanoFil™ syringe system effectively.

When you are looking for a low toxicity adhesive with some elasticity and good moisture resistance, choose a silicone adhesive.

Sylgard is a 2-part silicone elastomer with a very low dielectric constant, which makes it ideal for patch clamping and many other lab applications, especially in electrophysiology. The twin pack is a convenient, single use sleeve containing both parts of the adhesive. We will show you how to properly mix the Sylgard Twin Pack.

Both Kwik-Sil and Kwik-Cast are silicone adhesives, but they are a little different.

WPI EndOhm chambers are used with WPI's EVOM2 meter for making TEER (transepithelial electrical resistance) measurements. Here Subhra shows the difference between hanging cell culture inserts and standing cell culture inserts.

The EVOM™ Auto automates measurements of TEER in epithelial or endothelial monolayers cultured on 24-well or 96-well high throughput screening (HTS) plates utilizing our innovative EVOM technology, qualitatively measuring cell monolayer health and quantitatively measuring cellular confluence by reaching an increase or a plateau in tissue resistance. The autosampler has a 3-well rinse station for cleaning and stabilizing the electrodes. Now, sterile disposable rinse station inserts are available for your convenience. They fit over the 3-well base rinse station. You can simply throw out the disposable inserts with the solutions when you are changing plates. This short videos shows how easy they are to use.

EVOM™ Auto, with both 24 and 96 HTS multiwell plate capability, is a high throughput screening (HTS) platform offering fast, noninvasive sample scanning by comparing electrical resistance measurements (transepithelial/transendothelial electrical resistance: TEER). TEER measurement experiments are simple to set up and less time consuming than more complex molecular studies. TEER measurement can be used as the primary scanning method to identify any physiological changes that can then be further evaluated by other methods. EVOM™ Auto can capture TEER measurements in 24 and 96 HTS multiwell plates from Corning, Millipore, or MatTek. The sample preparation time in these HTS plates is efficient, allowing for fast, multi-channel pipetting options.

The EVOM™ Auto autosampler ships with a red electrode array lock in place to prevent the electrode array connection port from moving during transit. Here you can see how to easily remove it without damaging the lock or the autosampler.

The WPSS01 skin stapler is an affordable, reliable solution for veterinary wound closures. A skin stapler is designed for the efficient closure of surgical incisions or wounds by applying surgical staples to the skin, reducing surgery time and time under anesthesia. Each disposable skin staple cassette contains at least thirty-five (35) 316L stainless steel staples.

Each reusable skin stapler handle is provided sterile with one disposable staple cassette already loaded into the handle. Discard the disposable staple cassette after the procedure. The reusable handle may be cleaned and resterilized (autoclave, EO) for subsequent procedures and will effectively deploy at least twenty (20) disposable staple cassettes and withstand at least twenty (20) autoclave cycles.

Let’s take a look at how to set up a Digital Rat/Mouse, Neonatal Rat Stereotaxic frame. In a few steps you will be up and running.

In 2022, the United States Food and Drug Administration (FDA) approved 37 new drugs, of which 20 were chemical entities and 17 were biologics. In 2023, drug discovery remains strong with many new advancements a result of changing landscapes in both the types of drugs that are being developed and the new and innovative assay that are being launched to evaluate drugs preclinically. Therapeutic development is still highly focused on diseases that affect large populations of people for which there are lack of effective treatments, with 2023’s most anticipated drug launches expected to be in areas of cancer, Alzheimer’s disease, cardiovascular disease, and ulcerative colitis.

If the EVOM™ Auto software switches from Resistance to TEER mode while you are selecting menu options, here's a quick tip:

Be careful when selecting Resistance mode, do not tap the background window and do not click on the side arrows.

Tapping the background window will switch you to TEER mode.

Instead, tap an option on the forefront square window to stay in Resistance mode.

The EVOM™ Auto automates measurements of TEER in epithelial or endothelial monolayers cultured on high throughput screening 96-well plates utilizing our innovative EVOM™ technology, qualitatively measuring cell monolayer health and quantitatively measuring cell confluence by determining an increase or a plateau in tissue resistance.

The video below shows you how to schedule an operation on the EVOM™ Auto:

The EVOM™ Auto automates measurements of TEER in epithelial or endothelial monolayers cultured on high throughput screening 96-well plates utilizing our innovative EVOM technology, qualitatively measuring cell monolayer health and quantitatively measuring cell confluence by determining an increase or a plateau in tissue resistance.

The video below shows you how to stabilize the electrode array on the EVOM™ Auto:

The EVOM™ Auto automates measurements of TEER in epithelial or endothelial monolayers cultured on high throughput screening 96-well plates utilizing our innovative EVOM™ technology, qualitatively measuring cell monolayer health and quantitatively measuring cell confluence by determining an increase or a plateau in tissue resistance.

The video below shows you how to download and how to delete a data file EVOM™ Auto:

The EVOM™ Auto automates measurements of TEER in epithelial or endothelial monolayers cultured on high throughput screening 96-well plates utilizing our innovative EVOM™ technology, qualitatively measuring cell monolayer health and quantitatively measuring cell confluence by determining an increase or a plateau in tissue resistance.

The video below shows details the features and functions of the Experiment window on the EVOM™ Auto:

The EVOM™ Auto automates measurements of TEER in epithelial or endothelial monolayers cultured on high throughput screening 96-well plates utilizing our innovative EVOM™ technology, qualitatively measuring cell monolayer health and quantitatively measuring cell confluence by determining an increase or a plateau in tissue resistance.

The video below shows you the features of the homepage on the EVOM™ Auto:

Have you got the new EVOM Auto TEER Measurement System for 96-well HTS plates? This short videos shows how easy it is to setup.

EVOM™ Manual is WPI's newest instrument to measure Trans Epithelial Electrical Resistance (TEER). Let's look at what comes with the system and how easy it is to setup.