A Brief Guide to Lab Scissors in Ophthalmology

Precision and control are vital in ophthalmic procedures, and having the right surgical scissors makes all the difference. WPI offers a large variety of high-performance scissors specifically suited for the demands of eye surgery and laboratory microdissection work. Here's a quick guide to some of the most commonly used types of ophthalmic scissors.

Enhancing Quality Control in Cell Therapies

Cell therapies have revolutionized the field of regenerative medicine, offering promising treatments for a variety of medical conditions. Maintaining the safety, efficacy, and consistency of cell-based therapies is paramount for their successful application in clinical settings. Quality control measures play a vital role in evaluating the quality of these therapies, from development to administration. This article explores the current approaches to quality control in cell therapies, including the utilization of functional measurement techniques such as transepithelial electrical resistance (TEER), to ensure the quality and safety of these promising treatments.

Quality Control of Retinal Pigment Epithelial Cell Therapies

Cell therapies have emerged as a promising approach for treating various medical conditions, offering the potential for regenerating damaged tissues, restoring normal cellular function, or even acting as cytotoxic cells that target and destroy diseased cells such as cancer cells. As the field of cell-based therapeutics and regenerative medicine continues to advance, ensuring the quality and safety of cell-based therapies is of paramount importance. Quality control measures play a critical role in the manufacturing process of cell therapies, with trans-epithelial electrical resistance (TEER) emerging as a valuable tool for assessing the integrity and functionality of cells used in these therapies. Here, we highlight the use of TEER for quality control of Retinal Pigment Epithelial (RPE) cells, a promising cell therapy for degenerative retinal diseases1.

TEER in Ophthalmology for Advanced Research with RPE Cells

Transepithelial electrical resistance (TEER) has emerged as a powerful tool in ophthalmology research and has become a standard method for study of retinal pigment epithelial (RPE) cell biology and the development of these cells as a therapeutic for retinal diseases such as Age-Related Macular Degeneration (AMD). The application of TEER in assessing the barrier function and integrity of RPE cell layers has significantly advanced our understanding of retinal diseases and paved the way for innovative therapeutic interventions including some of the most promising cell therapies to date. This article explores the use of TEER in ophthalmology research, with a focus on studies utilizing RPE cells for both research and clinical applications.