Carbon fiber microelectrodes have been used in both the detection of ox­i­diz­able compounds (Gonon, et al., 1978; Cahill and Wightman, 1995) and extracellular single-unit re­cord­ing (Armstrong-James and Millar, 1979). WPI’s ultra-sensitive and low-noise carbon fiber (CF) electrodes can be ap­plied, with our Micro-C Poten­tio­stat or similar in­stru­ments, in the electrochemical detection of cat­e­chola­mines (epi­neph­rine, norepinephrine and dopamine), indolamines (serotonin, 5-HT or melatonin), ascorbic acid, Fe (II), and other ox­i­diz­able compounds.