Gas Tight Injection System

WPI’s NanoFil™ is a specially designed, gas-tight microliter syringe developed specifically for ultra-precise, low-volume fluid transfer that boasts consistency in its performance—with virtually zero dead volume. Microliter-level injections with NanoFil™ provide incredible accuracy with results you can trust.

Benefits

  • Virtually zero dead volume microinjection syringe
  • Strong gas-tight seal providing both repeatability and superior application outcomes
  • NanoFil™ needle sizes offered from 26G, down to 36G
  • Two needle types available–blunt and beveled
  • Versatile for life science research applications requiring precise in vivo targeting, low-volume fluid transfer
  • Compatible with WPI’s UMP3 microinjection system

Gas-Tight Control

Gas-tight control is particularly critical for applications requiring utmost accuracy and precision during low-volume fluid handling. Having a quality gas-tight design ensures a vacuum-like seal between the syringe and needle, supplying the necessary force to advance small samples forward during delivery, and upwards during withdraw. NanoFil’s virtual zero dead-volume comes from its thoughtfully designed coupling mechanism, where all WPI NanoFil™ needles insert directly into the syringe barrel, creating a 1:1 connection with the syringe’s plunger. Priming your syringe is made effortless with unparalleled control, supported by a sure-seal, gas-tight system.

Functionality, Versatility

WPI’s NanoFil™ promotes a range of applications, supported by our universal NanoFil™ needles – where all gauges are fully interchangeable and compatible with all NanoFilTM syringes.
NanoFil™ Intraocular (IO) and Retinal Pigment Epithelium (RPE) kits diversify the integration for fine-tuned fluid transfer into sensitive tissue, mitigating user error. NanoFil™ syringes easily attach to WPI’s UMP3 syringe pump paired to a stereotaxic or manipulator-fixed setups for enhanced control.

Selecting the Correct Needle

NanoFil™ syringes are packaged with a beveled 26G needle, but smaller gauges are usually preferred for in vivo applications requiring localized targeting of sensitive soft tissues , as well as tedious ex-vivo low-volume sample dispensing. NanoFil™ needles come in 26G, 33G, 34G, 35G, and 36G blunt or beveled styles. Each needle is handcrafted and individually tested by the WPI team to ensure quality and functionality. Currently, WPI carries the smallest commercially available needle gauge on the market at 36G. The sharpness of our unique tri-tip bevel offers a less invasive, smooth entry into tissue compared to single-cut bevels offered by competitors.

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  • MICROINJECTION

    For accurate, repeatable sample delivery, check out our microinjection range. WPI has manufactured the leading stereotaxic microinjectors, the UMP3 and NANOLITER, for over 30 years. Our gas tight microliter syringes, the NanoFilTM, offers the most accurate low-volume sample delivery on the market with zero dead volume, at a fraction of the cost to competitors.

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