WPI Blog

Neuroscience Cannulas for in vivo Investigation of Rodents

The WPI cannula system for neuroscience study and pre-clinical research includes an entire range of cannula options. You are guaranteed:

  • Exceptional Quality
  • Best Prices
  • Rapid Order Response

Choosing a Microscope Camera

It is common for a researcher to attach a camera to a microscope. Three types of cameras are available, and two are suitable for microscopy work:

Adjusting a Microscope

These instructions describe how to properly focus a binocular microscope.

How To Test Your EVOM2 Meter

The World Precision Instruments (WPI) EVOM2 is used for making trans epithelial electrical resistance (or TEER) measurements. We recommend that you test your EVOM2 before you use it for the first time and then periodically after that. If there is a concern that the meter or the electrode is not functioning properly, test the meter first. This video shows how to test the meter.

How to Fill a 2 mm Sensor Sleeve with Filling Solution

In this video, Nikki demonstrates how to prepare and fill a 2mm biosensor and prepare to calibrate an ISO-OXY-2 oxygen sensor. 

How to Calibrate an ISO-HPO100

In this video, WPI Chemist Nikki Scafa demonstrates how to calibrate the WPI ISO-HPO100 hydrogen peroxide microsensor. 

EVOM2-How to Equilibrate Your STX2

The World Precision Instruments (WPI) EVOM2 is used for making trans epithelial electrical resistance (or TEER) measurements. Two silver/silver chloride pellets are used for the electrodes. The chloride ion tends to migrate, which is a reversible reaction. But, because of this chloride ion swapping, the electrodes need to be polarized before each use. Before using the meter for making voltage measurements, equilibrate the electrodes. This video shows you how.

A Visual Catalog of Electrode Holders

Take a look at the variety of microelectrode holder available for your applications.

Muscle Physiology Basics

When building any structure, whether it’s a bridge or a protein, three elements are required:

  • Building materials
  • Energy
  • Building plans

The same is true in biological systems:

Exploring the Intracellular World

All living cells maintain a difference in electrical charge between the solutions that are inside and outside the cell membranes. The voltage difference across the cell membrane is usually at a steady level known as the resting membrane potential. The resting membrane potentialis produced by the differential distribution of ions on either side of the membrane. In muscle fibers, the potassium concentration inside the cell is over 50 times greater than the ion’s concentration in the extra­cellular fluid. On the other hand, the concentration of sodium is 10 times greater outside the membrane than inside. The concentration gradient of potassium is greater and in the opposite direction to the sodium concentration gradient. The ion concentrations are governed by three factors:

Vibration Free Workstation/Platforms Defined

WPI offers both vibration free workstations and platforms, and each is custom-built to meet your specifications. This article describes the options available and how to request a price quote for the unit you need.

The vibration-free platform looks like the one shown (left). The workstation tables are similar. These vibration-free units offer vertical and horizontal vibration isolation, high performace active-air suspension and automatic leveling. The diagrams below show dimensions of the workstations.

Choosing a Cuvette: Optical Glass or Quartz

This chart allows you to compare the various spectroscopy cuvettes that are available in nine different styles.

WPI Sensors are Out of this World

WPI sensors have been selected for use in the space shuttle by the European Space Agency. After six months evaluating numerous sensors of various worldwide companies, the European Space Agency chose WPI sensors for pilot experiments in its space shuttle. WPI President, Cliff Bredenberg and Chief Scientist, Dr. Xueji Zhang will visit Italy in July to finalize the sensors and electronics design.