The EVOM™ Auto automates measurements of TEER in epithelial or endothelial monolayers cultured on high throughput screening 96-well plates utilizing our innovative EVOM™ technology, qualitatively measuring cell monolayer health and quantitatively measuring cell confluence by determining an increase or a plateau in tissue resistance.

The video below shows details the features and functions of the Experiment window on the EVOM™ Auto:

World Precision Instruments' (WPI) legacy Robotic Epithelial Measurement System (REMS) and the new advanced, upgraded version of REMS, EVOM™ Auto, are high-throughput, automated transepithelial/transendothelial electrical resistance (TEER) measurement systems. These robotic systems, combined with EVOM™ technology, expedite TEER measurements.

Have you got the new EVOM Auto TEER Measurement System for 96-well HTS plates? This short videos shows how easy it is to setup.

EVOM™ Manual is WPI's newest instrument to measure Trans Epithelial Electrical Resistance (TEER). Let's look at what comes with the system and how easy it is to setup.

WPI's EVOM system is popular in the research community, both in academia and in industry, and it is commonly used for the evaluation of mammalian cellular health by measuring transepithelial/transendothelial electrical resistance (TEER or TER) of cellular layers. 

EVOM™ Manual is powered by the same EVOM™ technology as older EVOM models (EVOMX, EVOM, EVOM2 and EVOM3). It has advanced features for performing experiments more easily. With the new touchscreen display you can now store data as Microsoft® Excel files on a USB flash drive. Just remove the flash drive with all your recorded data from the EVOM™ Manual and plug it into a computer to access and plot your data. It is as simple as it sounds.

WPI’s EVOM™ Manual is the gold standard for delivering stable and repeatable Trans Epithelial Electrical Resistance (TEER) measurements. The EVOM™ Manual qualitatively measures cell monolayer health and quantitatively measures cell confluence by determining an increase or a plateau in tissue resistance detected using our innovative EVOM™ technology. The main display window has lots of information. Here’s a quick overview. You can download the infographic for a handy reference.

WPI’s EVOM™ Manual is the gold standard for delivering stable and repeatable Trans Epithelial Electrical Resistance (TEER) measurements. The EVOM™ Manual is the newest TEER meter. It qualitatively measures cell monolayer health and quantitatively measures cell confluence by determining an increase or a plateau in tissue resistance detected using our innovative EVOM™ technology. WPI’s state of the art EVOM™ technology provides you with real-time, valuable feedback during experimental measurements.

The new STX4 electrode works with the EVOM3, and the blades are replaceable. EVOM3 is used for making TEER (TER) Measurements in cell culture plates. Here's a quick tutorial to show you how to replace the blades.

The process of drug discovery and development is extremely slow and expensive. Regulatory authorities, such as US FDA need animal models to test absorption, distribution, metabolism, and excretion (ADME) which estimates safety and effectiveness of a drug. 

One of our frequently asked questions (FAQs) concerns TEER measurements with an EndOhm. If the resistance readings from your ENDOHM don't stabilize, you may need to do some troubleshooting.

The EVOM2 is the classic, hand-held instrument for making Trans Epithelial Electrical Resistance (TEER) measurements. The REMS system adds a robot and data recording for automated TEER measurements. There may be times when you don't have a robot, but would still like to have the data recording capabilities of the REMS system. With a little ingenuity, you can do just that. Here, we will show you how you can add data recording to your standard EVOM2.

With the development of a High Throughput Screening (HTS) protocol for faster drug discovery, a new line of cell culture filter plates have been introduced by several major cell culture insert manufacturers. These HTS plates normally have either 24 or 96 individual cell culture inserts "bonded" together as one plate so that it can be handled by a robot apparatus. In response to these developments, WPI has developed an automatic REMS system and a manual electrode, STX100, for TEER measurements using HTS plates.

Transepithelial Electrical Resistance TEER measurements is the most convenient, reliable and non-destructive method for evaluating and monitoring the growth of epithelial tissue cultures in vitro. The confluence of the cellular monolayer is quickly determined by a sharp increase in TEER. TEER measurement technology, which was first introduced by WPI in the mid-1980's, has since been perfected and expanded to include a range of TEER related manual and automatic instrumentation, including:

EVOM² - Manual TEER measurement of epithelial cells in 24- and 96-well plates
REMS AutoSampler - Automated system for High Throughput Screening (HTS)

EVOM was the first instrument designed to perform routine Trans Epithelial Electrical Resistance (TEER) measurement in tissue culture research. EVOM2 is the next generation, redesigned for greater usability.