ElveFlow OB1 Microfluidic Pressure Regulator

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OB1-1-200


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Prices valid in USA, Canada, and PR only.

WPI now introduces ElveFlow's OB1 line of microfluidic pressure controllers, boasting top-of-the-line accuracy driven by Piezoelectric technology. The OB1 line is offered with 1 to 4 channels,  with pressure & vacuum control. The OB1 series pumps can be paired with a flow sensor for utmost accuracy of flow control. These pumps offer the highest precision and responsiveness for your flow regulation needs on the market, and may be configured for full automation. 



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Order code Elveflow Cross Reference SKU Description
OB1-1-200 OB1_4-1000 ElveFlow OB1 Pressure Regulator, Single Channel, Eject Only, 200mbar
OB1-1-2000 OB1_4-2000 ElveFlow OB1 Pressure Regulator, Single Channel, Eject Only, 2000mbar
OB1-1-8000 OB1_4-3000 ElveFlow OB1 Pressure Regulator, Single Channel, Eject Only, 8000mbar
OB1-1-1000 OB1_4-4000 ElveFlow OB1 Pressure Regulator, Single Channel, Push/Pull, 1000mbar
OB1-1-6000 OB1_4-5000 ElveFlow OB1 Pressure Regulator, Single Channel, Push/Pull, 6000mbar
OB1-2-200 OB1_4-1100 ElveFlow OB1 Pressure Regulator, Dual Channel, Eject Only, 200mbar
OB1-2-2000 OB1_4-2200 ElveFlow OB1 Pressure Regulator, Dual Channel, Eject Only, 2000mbar
OB1-2-8000 OB1_4-3300 ElveFlow OB1 Pressure Regulator, Dual Channel, Eject Only, 8000mbar
OB1-2-1000 OB1_4-4400 ElveFlow OB1 Pressure Regulator, Dual Channel, Push/Pull, 1000mbar
OB1-2-6000 OB1_4-5500 ElveFlow OB1 Pressure Regulator, Dual Channel, Push/Pull, 6000mbar
OB1-3-200 OB1_4-1110 ElveFlow OB1 Pressure Regulator, Three Channels, Eject Only, 200mbar
OB1-3-2000 OB1_4-2220 ElveFlow OB1 Pressure Regulator, Three Channels, Eject Only, 2000mbar
OB1-3-8000 OB1_4-3330 ElveFlow OB1 Pressure Regulator, Three Channels, Eject Only, 8000mbar
OB1-3-1000 OB1_4-4440 ElveFlow OB1 Pressure Regulator, Three Channels, Push/Pull, 1000mbar
OB1-3-6000 OB1_4-5550 ElveFlow OB1 Pressure Regulator, Three Channels, Push/Pull, 6000mbar
OB1-4-200 OB1_4-1111 ElveFlow OB1 Pressure Regulator, Four Channels, Eject Only, 200mbar
OB1-4-2000 OB1_4-2222 ElveFlow OB1 Pressure Regulator, Four Channels, Eject Only, 2000mbar
OB1-4-8000 OB1_4-3333 ElveFlow OB1 Pressure Regulator, Four Channels, Eject Only, 8000mbar
OB1-4-1000 OB1_4-4444 ElveFlow OB1 Pressure Regulator, Four Channels, Push/Pull, 1000mbar
OB1-4-6000 OB1_4-5555 ElveFlow OB1 Pressure Regulator, Four Channels, Push/Pull, 6000mbar

Cutting-edge Microfluidic Flow Controller

Designed by scientists, for scientists. The versatile and powerful ElveFlow OB1 MK4 pressure controller provides the perfect flow control for all kinds of applications requiring utmost control and accuracy. Whether you need pressure or vacuum control, at an ultra low or high flow rate, or for short to week-long studies, the OB1 MK4 is the ideal instrument for your microfluidic needs.

OB1-shcematics

 

01 OB1 MK3 Pressure controller

The Best Performance in the Market: Piezoelectric Technology

The Elveflow OB1 MK4 is the only microfluidic flow control instrument worldwide to use piezoelectric 
regulators. The piezoelectric technology gives you 20 times more precise and 10 times faster 
flow control than any other flow controller on the market.

 

OB1 microfluidics flow controller

Customizable & upgradable

 -A modular system, up to 4 channels, and 5 pressure  & vacuum ranges      available

 -The OB1 MK4 can be configured according to your needs. In one piece of      equipment, you can have up to 
 -4 pressure and/or vacuum channels (and other customized options). If your    needs change, the instrument 
can be upgraded later, in any way you want.

 

 

04 MFS Standard flow rate sensor ELV

Get the Fastest Flow Rate Control: Pair with a Flow Sensor

-Connect the OB1 MK4 to a water resistant liquid flow rate sensor for use with single solution workflows (MF1-5+), or our premium Coriolis flow sensors. Coriolis BFS flow sensors are suited to work with both liquid and gas: directly control the flow rate in your chip using multiple solutions. The OB1 MK4 system continuously calculates the pressure and maintains the desired and constant flow rate paired with flow sensor feedback.

 

01 Software ELVEFLOW MICROFLUIDICS 3

Full control software, SDK, and UART communication

 -Single and intuitive software to get started in a few clicks and automate the  most complex and long
experiments. The SDK libraries allow you to control the OB1 MK4 using your  own code while connecting
it to other instruments. The MK4 is also equipped with UART communication  protocol in addition to the
 ESI and SDKs control, allowing it to communicate with most control systems, such as Mac, Linux, Arduino, 
PLC.

Advantages of Pressure Control in Microfluidics

  • Fast settling time (down to 40ms)
  • High stability and pulseless flow
  • Possibility to handle fluid volumes of several liters
  • Enable both flow and pressure control when used with a flow meter

Capture decran

For more details about Pressure driven flow control, please read these Application notes.

Get the Perfect Microfluidic Instrument

ELVEFLOW PRESSURE CONTROLLER

 

Directly connect a flow sensor

Control the flow inside your microfluidic setup

ELVEFLOW flow sensor draw

By connecting a MFS or BFS 
Flow Sensor to the OB1 MK4, 
you enable direct rapid and
precise regulation of the flow 
rate. The PID algorithm of the 
software reads the flow rate 
and adjusts the pressure 
accordingly to reach the target 
flow rate with speed and precision.

5 pressure ranges for each channel

Choose the pressure range best suited to your needs
WPI offers several ElveFlow pressure channel options available covering a wide range, up to 8000 mbar (116 PSI) and down to 
-900 mbar (-13 PSI). Choose the pressure channel that covers your experimental pressure requirements.

Groupe 1279

 

 

Choose between 1 to 4 channels, and more…
How many channels do you want?

The OB1 MK4 is a compact module that can accommodate up to 4 channels (pressure and/or vacuum). Each module can be upgraded at any time and have channels added or changed. You can control as many channels as you want with one computer.

Elveflow add channels

Need more channels on one module (8, 16, 64…. or even more)? Our custom service would design a specific pressure controller that fits your needs.

Software

software

A free software for all instruments
Powerful, modular and versatile set-up control solution
The ESI software can control up to 16 Instruments through the same interface. Thanks to TTL triggers you can synchronize your Elveflow system with any other instrument used in your laboratory (microscope or any electrical instrument … ). The Scheduler is a user-friendly tool to automate complex steps of your experiments and protocols.

 

 

 

 

Options

module reservoir

module ruler

module bubble

module calibration

Volume Injection Module
Enter your targeted volume and this module will automatically adjust the flow rate at the right time to inject it.
Fluidic System Optimization Module
Automatic diagnostic of the fluidic path sizing and recommendations to improve your microfluidic setup.
Bubble Detection 
Module
Do not suffer anymore because 
of bubbles! Quickly detect air in 
your set up to ensure rapid 
removal and avoid data confounds.
Sensor calibration module
Don’t lose precious time in calibration protocols.

 

Resources

OB1 MK4 User Manual

What is a Microfluidic Pressure-Driven Flow Controller?

Unboxing the OB1 Microfluidic Pump

Download Software & SDK for Elveflow Smart Interface

User Friendly and Cost Effective

  • Cost-effective solution: one sensor’s operating range covers the ranges of several standard microfluidic sensors.
  • No calibration required
    Stand alone sensor: plug the sensor directly to your computer to measure the flow rate.
  • Excellent repeatability and long-term stability
  • Excellent accuracy: down to 0.2 % of measured value accuracy
  • Easy to install and use
  • Low risk of gas bubble inclusion

How does a Coriolis flow meter work?

A microfluidic Coriolis flow sensor contains a U-shaped loop which constantly vibrates. When a fluid flows through this vibrating loop, Coriolis forces are generated and bend or twist the tube. The extremely small tube displacements are detected by sensors and fed to the electronic board. Since the measured phase shift is proportional to the mass flow, the Coriolis flow rate sensor measures the mass flow directly. This measurement principle is very accurate, fast and, more importantly, independent of the properties of the fluid (density, temperature, viscosity, pressure, heat-capacity or conductivity).

Coriolisflow

FAQ

Q: What pressure range should I choose?

A: The performances of the OB1 (for example, the pressure stability) is tied to the full operating pressure range. In order to achieve optimum performance, we recommend our users to choose the smallest pressure range that covers the required experimental pressures.

Q: Can I achieve direct flow control?

A: PID LOOP FOR FLOW CONTROL
By coupling a MFS or BFS flow sensor to the  OB1 flow controller, you can use the software to directly control the flow rate by directly inputting the flow rate value. The EIS software uses a PID loop to control the flow rate by setting automatically the pressure to reach the requested flow rate. Doing so, you can benefit of the best of the two worlds to get a fast and precise (pressure driven) volume flow rate (flow sensor).

Q: Do I need a pressure and/or vacuum source to operate the OB1 pressure controller?

A: Yes, you will need a pressure source to work with the OB1 pressure controller. You can either use the air supply of your lab if there is one, use a compressed air bottle or use an air compressor. WPI supplies compressors selected by Elveflow that are perfectly fitted for most application using the OB1. If your OB1 has a vacuum channel, you will need a vacuum pump. WPI also supplies Elveflow external pumps that work perfectly with the OB1.

Specifications

This table summarizes the main specifications of the Elveflow® OB1 MK4 pressure controller. To provide quality & performance, all of our instruments are tested and calibrated independently (response time, stability, repeatability… ) after being assembled and all test results are kept.

OB1 Table

*Non-contractual information, may be changed without notice 

  1. Max pressure value might vary by +/- 2.5% 
  2. Pressure stability (standard deviation) measured over the full pressure range with an external high accuracy pressure sensor (Druck DPI150) (3) Time required to reach 5% of the setting point. Depends on the computer operating system (4) Time required to reach 95% of the set point. Volume dependent – Measurement was done on 12 mL reservoir for a set point from 0 to 200 mbar (5) A vacuum source is mandatory for calibration and use of dual channels even if the channels are to be used in pressure only.
FLOW CONTROL
Flow sensor compatibility Compatible with the whole MFS and BFS range
Monitoring and feedback loop flow control available
Flow rates From 0,1 µL/min to 500 mL/min
(indicative, please refer to the MFS and BFS series)
Liquid Compatibility Non contact pump
Any aqueous, oil, or biological sample solution.
CONTROL & MONITORING
Software control Elveflow Smart Interface
Windows 7, 8 and 10, both 32 and 64 bit versions supported
Software
Development Kit
Librairies available: Matlab, Python, Labview, C++
Windows 7, 8 and 10, both 32 and 64 bit versions supported
Serial/UART communication protocol on request
Data management Possibility to log and extract data (.csv): channel and sensor detailed information using ESI
Input profiles Possibility to load profiles: ramp, sine, triangle, square or custom
Automation Generate step-by-step sequences using the ESI built-in sequencer
Load and save custom configurations (.csv)
Screen LCD screen showing pressure and sensor from the channel
ELECTRICAL CONNECTION
USB connection USB B
Sensor connection One M8-4 pins connecter available per channel
Compatible with Elveflow sensors: MFS, MPS, MFP, MBD
Custom analog sensor supply: 5-24VCustom analog sensor readout : 0-10V
TTL trigger In and out available
0-5V
OTHER
Power consumption 12 W (100 V to 240 V – 50 Hz to 60 Hz)
Casing dimensions (5) (length x width x height): 240 x 223 x 80 mm
Weight 1.4 kg to 2.9 kg

*Non-contractual information, may be changed without notice 

References

Chen, T., Gomez-Escoda, B., Munoz-Garcia, J., Babic, J., Griscom, L., Wu, P.Y., & Coudreuse, D. (2016). A drug-compatible and temperature-controlled microfluidic device for live-cell imaging. Open Biololgy, 6(8):160156. doi: 10.1098/rsob.160156

Orcheston-Findlay, L., Hashemi, A., Garrill, A., & Nock, V. (2018). A microfluidic gradient generator to simulate the oxygen microenvironment in cancer cell culture. Microelectronic Engineering, 195: p. 107-113. https://doi.org/10.1016/j.mee.2018.04.011

Yilmaz, E.G., & Inci, F. (2024). 3D breast cancer model on silk fibroin–integrated microfluidic chips. 3D Cell Culture, 2764: p.249-263. https://doi.org/10.1007/978-1-0716-3674-9_16

Xu, M., Zhao, H., Chen, J., Liu, W., Li, E., Wang, Q., & Zhang, L. (2020). An integrated microfluidic chip and its clinical application for circulating tumor cell isolation and single-cell analysis. Cytometry A., 97(1):46-53. doi: 10.1002/cyto.a.23902

...And many more! Check out additional OB1 peer-reviewed publications on ElveFlow's publication search engine here.