EVOM™ AUTO for TEER Measurement In 24/96 HTS Plate

EVA-MT-03-01

Options

Prices valid in USA, Canada, and PR only.

World Precision Instruments (WPI), the global leader in TEER technology, is proud to introduce the EVOM™ Auto, our newest entry into our pioneering EVOM family of products. The EVOM™ Auto automates measurements of TEER in epithelial or endothelial monolayers cultured on high throughput screening (HTS) 24 and 96-well and plates utilizing our innovative EVOM technology, qualitatively measuring cell monolayer health and quantitatively measuring cell confluence by determining an increase or a plateau in tissue resistance.

Automated measurement of tissue resistance of  transwell cell cultures provides the advantages of speed and precision, minimizes the chances of contamination, and ensures the rapid availability of measured resistance data. EVOM™ Auto produces a low AC current that omits any adverse physiological effects of the measurement technique on the samples and is specially designed for the non-destructive, high throughput screening of epithelial/ endothelial cellular physiology (e.g.,  confluence of cellular monolayers, barrier integrity of cell cultures, cytotoxicity). To learn more about our warranty options, click here.

EVOM™ Auto GxP Module now available.

Details

Options

Order code Description
EVA-MT-03-01 EVOM™ Auto For TEER Measurement in 96 HTS Plate
EVA-MT-03-02 EVOM™ Auto For TEER Measurement in 24C HTS Plate
EVA-MT-03-03 EVOM™ Auto For TEER Measurement in 24M HTS Plate

System Includes

  • EVOM™ Auto (TEER Measurement System includes the Autosampler, 96 HTS or 24C (Corning) HTS or 24M (Millipore) HTS Electrode Array
  • Interface Unit and Cable
  • Control iPad with software
  • Power Cord

Applications

  • Epithelial and Endothelial Barrier Studies
  • Confluence
  • Cytotoxicity
  • Lung Viral Infection
  • Blood Brain Barrier (BBB)
  • Lung in vitro Models for COVID Studies
  • Intestine, Kidney and Liver Tissues

Our EVOM™ Auto is a Complete System

  • Most reliable and convenient method of evaluating and monitoring the structural integrity of epithelial tissue culture in vitro
  • High-throughput 24 and 96-well plate system for labs with high volume
  • Unparalleled measurement accuracy with continuous data recording capability
  • Measure cellular activity label-free and real-time
  • 96 well plate electrode array is compatible with a wide variety of 96-well HTS plates: Corning, Millipore, and MatTek
  • 24C electrode array for Corning 24 HTS plates and 24M electrode array for 24 well Millipore 24 HTS plate
  • Easy switch and measurement in different plate types (24 or 96) by swapping electrode array and plate adapters using the same system
  • With web-based software, no operating system or security upgrades are required

Features

Features Advantages Benefits
Electrodes available for 24 or 96-well HTS plates Measure 24 or 96-wells, a column  at a time (electrode array measures a column). Save time by automating your process and move through a plate quickly.
Easy switch options for different plate types By simply plugging in the right electrode array and matching plate adapter key, fast and easy switch between different HTS plate types (e.g., Corning 24, Corning 96) is possible. The users can perform experiments on different platforms (24 or 96 HTS plates or different 96 HTSs) analyze samples using the same system.  
Automate your measurements Streamline your workflow. Minimize human errors.
Three rinse locations You may rinse your electrodes multiple times during a measuring sequence. Take control of your protocol and define the sequence you need.
Crash protection System automatically detects a misalignment and pauses measurements to prevent equipment damage. Minimize probe damage and avoids costly repairs.
Auto-detection of electrode head System automatically detects your electrode and configures its position and software options for your plate. Hardware setup is easy and requires no configuration.
Intuitive touchscreen interface with browser-based software Programming your sequences is simple with simple selection options. Easy-to-navigate system saves time when configuring sequences.
Confirm or create a custom plate profile Can adjust the programmed coordinates. With complete control of the system, you can fine tune the programming as desired (e.g., plate type, sample depth).
Ability to save three plate coordinates per plate type (. e.g., Corning 96) Multiple (three) users can operate the instrument using their individual saved settings. Date and time stamps of the user plate profile changes help to keep track if the plate profiles were changed. Ensure consistent and error free measurements. 
Store all your data or export to Excel You can analyze your data in a manner suitable to your workflow. Flexibility to access and manage your data.

EVOM Auto Compatible High Throughput Transwell Plates 

24C Electrode Array
 		24 M Electrode Array  96 Electrode Array 
Corning HTS Transwell Corning Falcon HTS Multiwell Millicell-24 Millipore HTS96 Multiwell Corning Falcon Corning HTS Transwell MatTek 96 HTS Plates
3378 351181 PSHT010R1 PSHT004R1 351131 3380

CCI96-PET-0.4
3379 351183 PSST010R1 PSRP004R1 351161 3392  
3396 351185 PSMT010R1 PSRP004R5 351162 3381

CCI96-PET-0.4-5
3397 354803 PSET010R1 PSHT004S5 351163 3391  
3398 354804 PSRP010R1 PSHT004R5 351164 3385

CCI96-PET-CL-0.4
3399   PSRP010R5   353938 3386  
    PSHT010R5     3387 CCI96-PET-CL-0.4-5
          3388  
          3374  
          3384  

With additional electrode arrays, the same system can be used for other plate types

Electrode Array Part Numbers Product Description
EVA-EL-03-01 EVOM™ Auto 96 HTS Electrode Array For TEER
EVA-EL-03-02 EVOM™ Auto 24C HTS Electrode Array For TEER
EVA-EL-03-03 EVOM™ Auto 24M HTS Electrode Array For TEER

*24C = Corning 24                 

*24M = Millipore 24

Add-ons

Order code Description
EVA-MT-03-Upgr EVOM™ Auto EVA-MT-02-01 Upgrade to EVA-MT-03-01
EVA-MT-03-EX1 EVOM™ Auto 1 Year Premium Warranty
EVA-MT-03-EX2 EVOM™ Auto 2 Year Premium Warranty
EVA-MT-03-INS EVOM™ Auto On-Site Installation & Training
EVA-MT-03-IOQ EVOM™ Auto Instrument IQ/OQ  
EVA-MT-03-CAL EVOM™ Auto Annual Inspection and Calibration

Note

  • Premium warranties cover any accidental damages.
  • Premium warranties exclude cosmetic damages that do not impact performance of the instrument.
  • If premium warranties are not purchased with a new instrument, the premium warranties can be added afterwards with the purchase of EVA-MT-03-CAL.

Resources

Documents

Video

EVOM™ Auto: Benefits for Drug Discovery

 

EVOM™ Auto: How to add a Corning 24 Adapter and Electrode Array

 

EVOM™ Auto: How to Remove the Electrode Array

 

EVOM™ Auto: How to Set up the Interface Unit and Autosampler

 

Sterile Disposable Rinse Stations for EVOM™ Auto Offer Convenience

 

What is TEER

 

EVOM Auto Animation

Specifications

Type Description
Autosampler Dimensions (W×D×H) 16×10×8.4”
Autosampler Weight 15 lbs.
CE Certified Yes
CSA Certified Yes
UL Certified Yes
Compatibility
  • Corning, Millipore, MatTek 96-well
  • HTS Plates with 96 electrode array
  • Corning 24 HTS Plates with 24C electrode array
  • Millipore 24 HTS Plates with 24M electrode array
Resistance Range 10KΩ, 50KΩ, 100KΩ
Number of Rinse Stations 3
Electrode Array 
  • Array 8 pair of (1.2 mm φ) Electrodes: 96 well array
  • Array 4 pair of (1.2 mm φ) Electrodes:  24 well array 
Minimum Sample Reading Time 1 Second
Control Device for Running Software Tablet, Laptop, Desktop with Wi-Fi adapter
Output Data CSV/Microsoft® Excel