Kwik-Sil/Kwik-Cast Low Toxicity Silicone Bioadhesive/Sealant

  • kwik-sil-s-hand_1
  • kwik-sil-s
  • img_5716
  • img_5713-2
  • img_5712_1
  • kwik-sil-kwik-cast-tips
  • kwik-sil-s-0141-edit
  • kwik-sil-s-0147
  • kwik-sil-s-0151
  • kwik-cast-2024-hand
  • kwik-uncapped_1
  • kwik-cap_1
  • kwik-align-cap_1
  • kwik-cast-2024
  • kwik-align-cap
  • kwik-cap
  • kwik-cast-s-hand
  • kwik-cast-drip
  • kwik-cast-tip-filling_1
  • kwik-cast-s
  • kwik-uncapped
  • kwik-cast-s-0147
  • kwik-cast-s-0141-2
$137
$137

KWIK-SIL

From $85 - $137
From $85 - $137
Options

Prices valid in USA, Canada, and PR only.

Kwik-Sil™ (adhesive) and Kwik-Cast™ (sealant) are low-toxicity, biocompatible silicone elastomers designed for neuroscience, nerve studies, and live tissue applications. Delivered in a dual-barrel cartridge, the materials mix automatically during application, eliminating pre-mixing and simplifying workflows.

They cure rapidly at room temperature without generating heat, reducing the risk of tissue damage while maintaining consistent, reproducible results. Kwik-Sil™ dries clear and cures slightly faster for adhesion, while Kwik-Cast™ dries green and flows easily for sealing and embedding. Sterile options are available.

* New and Improved with Extended Shelf Life

* Returns Policy: Non-returnable/Non-refundable

COMPARE OPTIONS FOR YOUR PROTOCOL

ACCESSORIES

Details

Key Features

KWIK-SIL for Neuroscience Applications, Nerve Studies and More
  • Low-toxicity, biocompatible silicone for live tissue use and nerve studies
  • Rapid curing (within minutes at room temperature)
  • Cures without generating heat (reduces tissue damage)
  • No pre-mixing required (dual-barrel cartridge with mixing tips)
  • Medium-strength adhesion with elasticity and moisture resistance
  • 6-Month shelf life

Applications

  • Neuroscience and electrophysiology research
  • Embedded peripheral nerve studies (KWIK-CAST)
  • Electrode placement and stabilization
  • Tissue sealing and embedding (KWIK-CAST)
  • In vivo and in vitro experimental setups

Kwik-Sil™ vs Kwik-Cast™

Feature Kwik-Sil™ (Adhesive) Kwik-Cast™ (Sealant)
Primary use Adhesion Sealing / embedding
Viscosity Medium Very low (flows easily)
Color Clear Green (when color mixes)
Cure speed Faster Slightly slower (~3 min)
Standard Pkg 2 Dual Barrel Cartridges with 10 Mixing Tips 2 Dual Barrel Cartridges with 10 Mixing Tips
Sterile Pkg 1  Sterile Dual Barrel Cartridge with 5 Mixing Tips 1  Sterile Dual Barrel Cartridge with 5 Mixing Tips
Best for Chronic studies, electrode fixation Acute recordings, nerve embedding
KWIK-CAST

 

Why Kwik-Sil™ & Kwik-Cast™ Perform Better

Kwik-Sil™ and Kwik-Cast™ are formulated for use with live tissue, offering significantly lower toxicity than traditional RTV silicones. During curing, they release a small amount of hydrogen gas rather than acetic acid or alcohol, reducing the risk of cellular damage.

Both materials cure within minutes at room temperature without generating heat and are not inhibited by contact with biological tissue. This allows for reliable performance in applications such as electrode fixation, nerve embedding, and in vivo experimentation.

The result is a fast, reproducible silicone system that supports consistent outcomes across sensitive biological workflows.


    Choosing Between Kwik-Sil™ and Kwik-Cast™

    Kwik-Sil™ is best suited for applications that require stable adhesion over time, such as chronic peripheral nerve studies and long-term electrode fixation.

    Kwik-Cast™ is designed for embedding and sealing in acute recordings. It flows around tissue and electrodes to create a continuous seal that prevents fluid intrusion and supports stable signal acquisition. It can also be applied under mineral oil and allows easy electrode recovery after use.

    Choose Kwik-Sil™ for adhesion and durability in longer experiments, and Kwik-Cast™ for sealing, embedding, and short-term recording setups.

    Curing & Handling

    Kwik-Sil™ and Kwik-Cast™ cure within minutes at room temperature, providing a short, reliable working time for precise application.

    The silicone inside the cartridge cannot be sterilized by UV, gamma, H₂O₂, autoclaving, or EtO. For sterile workflows, use the pre-sterilized versions (KWIK-SIL-S™ and KWIK-CAST-S™).

    The exterior of the cartridge and mixing tips can be cleaned using 70/30 alcohol or liquid sterilants such as Cidex OPA (WPI P/N 7364-4) or Rapicide OPA (WPI P/N 504611).

    Evom Transcellular and Paracellular Pathway of Ion or Electrical Current Flow

    Kwik-Sil™ and Kwik-Cast™ come with a tip design engineered to completely mix the adhesive and minimize leakage.

    NOTE: This product is non-returnable/non-refundable. For details, please refer to the WPI Terms & Conditions.

    Resources

    KWIK-SIL Certification

    KWIK-CAST Certification

    KWIK-SIL/KWIK-CAST Instruction Manual

    KWIK-SIL Sell Sheet

    Kwik-Sil Kwik-Cast Instruction Manual

    Video

    5 Reasons KWIK-SIL & KWIK-Cast Adhesive are Ideal for Neuroscience Application

     

    KWIK-SIL versus KWIK-Cast, What's the Difference

     

    KWIK-SIL & KWIK-CAST: How to Install the Mixing Tip

    Specifications

    Type KWIK-SIL KWIK-SIL-S KWIK-CAST KWIK-CAST-S
    MIX RATIO 1 to 1 1 to 1 1 to 1 1 to 1
    WORKING TIME < 5 minutes* < 5 minutes* 4 minutes 4 minutes
    SETTING TIME (ROOM TEMP., 1:1 RATIO) 5–10 minutes** 5–10 minutes** <10 minutes <10 minutes
    CURE TIME ~15 minutes ~15 minutes ~15 minutes ~15 minutes
    VISCOSITY, CPS 15,000 15,000 10,000 10,000
    GUARANTEED SHELF LIFE AT 23 °C 6 months 6 months 6 months 6 months
    VOLUME 5 mL 5 mL 5 mL 5 mL
    NUMBER OF MIXING TIPS 10 5 10 5
    DEAD VOLUME OF THE MIXING TIP <0.12 mL <0.12 mL <0.12 mL <0.12 mL
    NOTE This is the consistency of pourable silicone rubber. This is the consistency of pourable silicone rubber. This is the consistency of chocolate syrup. This is the consistency of chocolate syrup.
    AFTER CURING 24 HOURS:
    TEAR STRENGTH, PPI 90 90 44 44
    ELONGATION % 650 650 60 60
    DUROMETER (SHORE A-2) 30 30 36 36
    COLOR translucent translucent green green
    VOLUME RESISTIVITY, W/CM 1x1015 1x1015 1x1015 1x1015

    * 3 minutes average with about 90 seconds of liquidity

    ** no longer mixable at this point

     

    FAQs

    How do I reduce bubbles in KWIK-SIL during curing?

    Bubbles are caused by hydrogen gas released during curing. Because the material cures quickly, the gas may not fully escape. To reduce bubbles, cool the material before use to slightly slow the curing process.

    Can Kwik-Sil™ or Kwik-Cast™ be sterilized after opening?

    No. The silicone inside the cartridge cannot be sterilized by UV, gamma radiation, H₂O₂, autoclaving, or EtO. For sterile applications, use the pre-sterilized versions (KWIK-SIL-S or KWIK-CAST-S).

    What is the difference between KWIK-SIL and KWIK-CAST?

    KWIK-SIL is designed for adhesion and long-term stability, making it ideal for chronic studies and electrode fixation. KWIK-CAST is formulated for sealing and embedding, flowing easily around tissue for acute recordings and short-term experiments.

    How long is the working time for KWIK-SIL/KWIK-CAST after dispensing?

    Working time is typically under 5 minutes, with curing completed in approximately 10–15 minutes at room temperature.

    Can the cured KWIK-SIL or KWIK-CAST material be removed after use?

    Yes. Once cured, the material can be gently removed. For example, it can be peeled away from rodent fur or tissue with minimal disruption when handled carefully.

    Kwik-Sil/Kwik-Cast Low Toxicity Silicone Bioadhesive/Sealant

    $137.00

    Related Products

    Related Articles

    • VIDEO: Reasons KWIK-SIL Adhesive is Ideal for Neuroscience Applications
      VIDEO: Reasons KWIK-SIL Adhesive is Ideal for Neuroscience Applications

      VIDEO: Reasons KWIK-SIL Adhesive is Ideal for Neuroscience Applications

      When you are looking for a low toxicity adhesive with some elasticity and good moisture resistance, choose a silicone adhesive.

    • VIDEO: KWIK-SIL VERSUS KWIK-CAST, What’s The Difference
      VIDEO: KWIK-SIL VERSUS KWIK-CAST, What’s The Difference

      VIDEO: KWIK-SIL VERSUS KWIK-CAST, What’s The Difference

      Both Kwik-Sil and Kwik-Cast are silicone adhesives, but they are a little different.

    • 4 Types of Silicone Adhesives for Life Science Applications
      4 Types of Silicone Adhesives for Life Science Applications

      4 Types of Silicone Adhesives for Life Science Applications

      The adhesive you select will depend largely on your biomedical research laboratory application. If you are building electrodes, you might use a silver-filled, conductive epoxy to connect a Ag/AgCl pellet. For instantaneous bonding when mounting a rodent brain slice, you might select an ethyl cyanoacrylate. When you are looking for a low toxicity adhesive with some elasticity and good moisture resistance, a silicone adhesive is the option of choice. When used with living tissue, an adhesive must be:

    • Lab Supplies Must Haves When You Need Them
      Lab Supplies Must Haves When You Need Them

      Lab Supplies Must Haves When You Need Them

      In any laboratory, having key lab supplies is almost as important as having the major equipment. Choosing a reputable supplier of these necessary supplies is as important as having quality laboratory supplies when you need them. WPI wants to be your partner in early drug discovery, and we stock a wide variety of lab supplies, many of which can ship the same business day. Having a variety of lab supplies ready to ship makes us a dependable research partner. Here are some of the popular supplies that we keep on hand to meet your needs for your upcoming experiment

    • What Are Laboratory Supplies? A Beginner-Friendly Overview
      What Are Laboratory Supplies? A Beginner-Friendly Overview

      What Are Laboratory Supplies? A Beginner-Friendly Overview

      If you’ve ever stepped into a research lab, you know it’s filled with specialized tools and equipment—all essential for keeping experiments running smoothly. When people ask “What are laboratory supplies” the short answer is: they’re the essentials that help scientists and researchers get their work done. That includes everything from basic items like petri dishes and pipettes to more advanced laboratory equipment like microscopes and micromanipulators.