Pulse Oximetry

Pulse oximetry is a non-invasive and painless test which measures oxygen saturation level.
It can rapidly detect even small changes in how efficiently oxygen is being carried to the extremities furthest from the heart, including the legs and the arms.

MouseOx® Plus Pulse Oximeter

MouseOx® Plus Pulse Oximeter

 World's first and only patented non-invasive vital signs monitor

  • for mice, rats, and other small laboratory animals.

M CollarClip™

M CollarClip™

CollarClip with Blank Clip

  • For use with Conscious Rodent, 31-100 gm


Benefits Of The MouseOx Plus Small Animal Pulse Oximeter

  • Arterial Saturation – The amount of oxygen bound to haemoglobin in mice, rats, and other small animals.
  • Heart Rate – Able to measure small animals with heart rates of 90 – 900 bpm.
  • Breath Rate – Provides breathing rate using the same sensor
  • Pulse Distension – Change in arteries at the Sensor site due to a heart beat
  • Breath Distension – Change in arteries at the sensor site sue to breathing
  • Temperature – Monitor subject core body temperature using the temperature probe
  • Activity – Monitoring gross motion of a subject over a period of time

 

Heart Rates Of 90 – 900 BPM

The MouseOx® Plus can be used on mice, rats and other small animals with a pulse rate of 90 – 900 bpm

Noninvasively Measure Up To 7 Parameters

Measure up to 7 physiological parameters without invasive surgical procedures

Anesthetized & Conscious Subjects

Special sensors and software modules allow you to monitor both anesthetized & conscious subjects.

Non-Magnetic MRI Compatible

Monitor your subject’s health during MRI imaging using the Non-Magnetic MRI Sensor

Monitor Up To 16 Individuals

Utilizing a Multiplexer, you can sequentially monitor up to 16 individuals one-at-a-time, using one MouseOx® Plus.

Analogue Output Of Pulse Waveform

Outputs the raw pulse waveform for input into other data acquisition systems 

 

Selecting A MouseOx Plus Small Animal Pulse Oximeter

MouseOx Plus

The MouseOx Plus (MOX-DC) package comes with the MouseOx Plus control unit, basic monitoring software and two sensors of your choice (excludes custom, non-magnetic and temperature sensors). Features include:

MouseOx Plus Standard Features
Software*

Parameters

  • Arterial Saturation (SpO2)
  • Heart Rate
  • Breath Rate
  • Pulse Distension
  • Breath Distension
Vital Signs Numeric Summary
Anesthesia Alarms
Hardware Analogue Pulse Signal Output

*See accessories section for module upgrades to enhance the software including adding the ability to record data, measure temperature and work with awake animals. 

MouseOx has a wide range of accessories available to enhance your ability to make measurements in many different environments and conditions.

MouseOx Plus Sensors

MouseOx Plus sensors have a service life of 100 hours to maintain measurement quality. An alert is displayed within the software to confirm the remaining service life of a sensor. The measurement will not be interrupted in the middle of an experiment.

Mouse Thigh Sensor

The Mouse Thigh Sensor is used with the  MouseOx Plus for obtaining vital sign measurements from an anesthetized mice by providing a strong signal from femoral artery.

Mouse Paw Sensor

The Mouse Paw Sensor is used for obtaining vital sign measurements from the paw of anesthetized mice. The sensor can be used to obtain measurements from a mouse tail.

Rat Foot Sensor

The Rat Foot Sensor is used with the MouseOx Plus for obtaining vital sign measurements from an anesthetized rat’s foot.

Throat Sensor

The Throat Sensor is used with the MouseOx Plus for obtaining vital sign measurements from an anesthetized animal in the supine position by obtaining a strong signal from the carotid arteries.

 

Collar Sensor

The Collar Sensor is used with the MouseOx Plus for obtaining vital sign measurements from a Concious or Anesthetized animal in the prone position by obtaining a strong signal from the carotid arteries.

The Collar type sensor comes with a blank clip to facilitate hair removal around the neck and to accustom the animal to the clip before measurement.

Non-Magnetic MRI Compatible Sensor

The Non-Magnetic MRI Compatible Sensor is for anesthetized subjects and can be used in small, large and closed bore MRI environments up to 19T.  The MRI Compatible Sensor can also be used in conjunction with MouseOx Plus Temperature Sensor.

Rectal Temperature Sensor

The MouseOx Plus can measure Mouse or Rat core body temperature with the addition of the Rectal Temperature Sensor and included Temperature Software.

 

 

Description Part Number

Mouse Thigh Sensor

  
Thigh Sensor: Anesthetized Mouse < 60 g; Rat <= 100 g MOX-SNSR-MTHGH

 

Mouse Paw Sensor

  
Mouse Paw Sensor MOX-SNSR-MPAW

 

Rat Foot Sensor

  
Rat Foot Sensor: Anesthetized Rat > 100g MOX-SNSR-RTFT

 

Throat Sensor

  
XS ThroatClip: Anesthetized Unshaved Mouse 1-15 g, Shaved Mouse 1 - 20 g MOX-SNSR-THRT-XS
S ThroatClip: Anesthetized Unshaved Mouse > 15 g, All Mice > 20 g; Rat 5 - 30 g MOX-SNSR-THRT-S
M ThroatClip : Anesthetized Rat 31 - 100 g MOX-SNSR-THRT-M
L ThroatClip:  Anesthetized Rat 101 - 300 g MOX-SNSR-THRT-L
XL ThroatClip: Anesthetized Rat 301 - 500 g MOX-SNSR-THRT-XL
2XL ThroatClip: Anesthetized Rat > 500 g MOX-SNSR-THRT-2XL

 

Collar Sensor

  
XS CollarClip w/ Blank Clip: Conscious Unshaved Mouse 1 - 15 g, Shaved Mouse 1 - 20 g MOX-SNSR-CLLR-XS
S CollarClip w/ Blank Clip: Conscious Unshaved Mouse > 15 g, All Mice > 20 g, Rat 5 - 30 g MOX-SNSR-CLLR-S
M CollarClip w/ Blank Clip: Conscious Rat 31 - 100 g MOX-SNSR-CLLR-M
L CollarClip w/ Blank Clip:  Conscious Rat 101 - 300 g MOX-SNSR-CLLR-L
XL CollarClip w/ Blank Clip: Conscious Rat 301 - 500 g MOX-SNSR-CLLR-XL
2XL CollarClip w/ Blank Clip: Conscious Rat > 500 g MOX-SNSR-CLLR-2XL

 

Non-Magnetic MRI Compatible Sensor

  
Thigh Sensor, Non-Magnetic Spring MOX-SNSR-MTHGH-NM
Rat Foot Sensor, Non-Magnetic Spring MOX-SNSR-RTFT-NM

 

Rectal Temperature Sensor

  
2m Temperature Sensor, Sensor Only MOX-SNSR-TEMP-2M
4m Temperature Sensor, Sensor Only MOX-SNSR-TEMP-4M
7m Temperature Sensor, Sensor Only MOX-SNSR-TEMP-7M

 

MouseOx Plus Accessories

Accessory

Premium Monitoring Software

Added functionality of software:

  • Vital Sign Real-Time Trends
  • Temperature and MRI monitoring (purchase of respective sensors required)
  • Scheduling Software
  • Diagnostic Averaging With Recording For Spot-Checking
  • File Recording And Event Marking
  • High speed data acquisition/recording (.tdms format)
  • Continuous “streaming” parametric data (15 Hz)
  • Continuous discrete data sampling (Snapshot) – user specified 
  • Cardiac PhotoPlethysmogram Recording (300 Hz)
  • Export all or parts of data files to “.tdms” or “.csv” formats for use with 3rd-party analysis software
Part Numbers

Premium Monitoring Software (MOX-SFTWMOD-REC)

Body Temperature Option

The MouseOx Plus Temperature Probe can be used to measure the core body temperature of a small animal or to monitor ambient temperature during experimental procedures. The sensor probe is made of implant grade titanium and is MRI compatible. Available in 2m, 4m and 7m lengths.

Part Numbers

Requires Premium Monitoring Software (MOX-SFTWMOD-REC) and a Rectal Temperature Sensor

Conscious Subjects Software

The Conscious Applications Software includes enhanced filters and control algorithms which optimize the MouseOx® Plus for use on conscious, moving subjects. (purchase of respective sensors required)

Part Numbers

Requires Conscious Subjects Software (MOX-SFTWMOD-CON) and Premium Monitoring Software (MOX-SFTWMOD-REC) and sensor(s) For Conscious Subjects

  • XS CollarClip™ w/ Blank Clip: Conscious Unshaved Mouse 1-15 gm, Shaved Mouse 1-20 gm (MOX-SNSR-CLLR-XS)
  • S CollarClip™ w/ Blank Clip: Conscious Unshaved Mouse > 15 gm, All Mice > 20 gm, Rat 5-30 gm (MOX-SNSR-CLLR-S)
  • M CollarClip™ w/ Blank Clip: Conscious Rat 31-100 gm (MOX-SNSR-CLLR-M)
  • L CollarClip™ w/ Blank Clip: Conscious Rat 101 - 300 gm (MOX-SNSR-CLLR-L)
  • XL CollarClip™ w/ Blank Clip: Conscious Rat 301 - 500 gm (MOX-SNSR-CLLR-XL)
  • 2XL CollarClip™ w/ Blank Clip: Conscious Rat >500 gm (MOX-SNSR-CLLR-2XL)

Conscious Measurement Enclosure (CME)

Animal holding chambers for conscious measurements – rat and mouse sizes

Part Numbers

Conscious Measurement Enclosure

  • Conscious Measurement Enclosure for Mice (MOX-STCME-M)
  • Conscious Measurement Enclosure for Rats (MOX-STCME-R)

MRI Compatible Oximeter Sensors

The Non-Magnetic MRI Compatible Sensor is for anesthetized subjects and can be used in small, large and closed bore MRI environments up to 19T.  The MRI Compatible Sensor can also be used in conjunction with MouseOx Plus Temperature Sensor.

Part Numbers

Sensors compatible for MRI

Contact WPI for other non-magnetic size options.

Analogue Data Output

The STARR-Link Analogue Output Module provides 0-5 V analogue outputs of the parameters (IR/PPG raw cardiac waveform) measured by the MouseOx Plus. It serves as an interface between the MouseOx Plus and other data acquisition hardware.

This module is primarily used for event triggering,

Part Numbers

STARR-Link Plus, Analogue Data Output Module (MOX-AOM)

Multiplexer

The Multiplexer is a sensor Switching Unit for MouseOx Plus that allows a single MouseOx Plus to monitor and record data from up to 16 subjects. The Multiplexer allows you to choose between automatic, scheduled, or manual switching.

Part Numbers

Select between 3 multiplexer options

  • 8 Channel Multiplexer allows you to monitor and record data from up to 8 subjects, using one MouseOx Plus control unit (MOX-MUX8-DC)
  • 8 Channel Multiplexer with Temperature allows you to monitor and record data from up to 8 subjects, using one MouseOx Plus control unit (MOX-MUX8X8-DC)*
  • 16 Channel Multiplexer allows you to monitor and record data from up to 16 subjects, using one MouseOx Plus control unit (MOX-MUX16-DC)

* Requires Premium Monitoring Software

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