NEW RELEASE! WPI Introduces Handheld-Sized 5 µL NanoFil™ Syringe for Precision Microinjection Research
Coming early in summer 2026, WPI is expanding the NanoFil™ syringe family with three new sizes: 5 µL, 25 µL, and 50 µL. Designed for researchers who require exceptional precision and control, these new syringes bridge the gap between our existing 10 µL and 100 µL models, providing more options for low-volume microinjection applications. Most exciting is the new handheld 5 µL NanoFil™ syringe, engineered to deliver ultra-small volumes with outstanding accuracy and ease of use.
Designed for the Ultra-Low Volume Targets
Precision delivery is critical in research, particularly within the ophthalmic and neuroscience sectors. Whether delivering viral vectors into the vitreous or the subretinal space, or performing experimental brain injections in small animal models, researchers are constantly balancing two competing priorities: achieving highly accurate dosing while minimizing tissue damage.
Traditional syringes and larger-volume injection systems often force investigators to compromise. A gas-tight, zero dead volume 5 µL NanoFil™ syringe is a game changer, providing unmatched precision, control, and ease of use for delicate procedures... and for the first time, handheld ones. It is the only of its kind on the market.
The result is greater control during delicate procedures and improved confidence when working with valuable research materials.
Why a 5µL Syringe Matters
Many ophthalmic and neuroscience applications require injection volumes well below the capacity of traditional syringes. When delivering expensive or limited-availability reagents, every microliter counts. WPI’s 5µL NanoFilTM syringe is purpose-built for delicate low-volume applications where variability in delivery cannot be endured. The smaller syringe volume paired with the signature NanoFil™ design enables:
- Greater dosing accuracy
- Improved volume resolution
- More efficient use of expensive reagents
- Reduced waste through a gas-tight, zero-dead-volume design
- A shorter barrel to support single-handed injection capability
This is particularly important when working with high-value materials such as AAV vectors, stem cell suspensions, antibodies, nanoparticles, and experimental therapeutics. In the ophthalmic/intravitreal field, being able to have this level of control, all while independently delivering samples by hand, without the need for another colleague depressing the plunger, greatly improves workflow efficiency and simplifies procedures.
Enhanced Control During Delicate Procedures
The eye and brain are among the most sensitive organs in the body. Even minor variations in injection speed or pressure can influence experimental outcomes. A handheld NanoFil™ syringe provides researchers with direct tactile control during procedures, allowing them to:
- Feel tissue resistance in real time
- Adjust injection speed naturally
- Maintain stable positioning under a microscope
- Reduce the risk of unwanted fluid delivery
- Reduce risk of undesired mechanical damage to tissue
For intravitreal, subretinal, intracameral, and suprachoroidal injections, this level of control can significantly improve procedural success rates. For general applications benefitting from the use of a 5µL syringe, researchers can enjoy the same compatibility as they do now with our 10 and 100µL NanoFil™ offerings, just on an enhanced accuracy scale.
Applications in Ophthalmic and Neuroscience Research
A handheld 5 µL NanoFil™ syringe excels in these areas, making it a valuable tool for laboratories investigating:
- Retinal gene therapy
- Optogenetics
- CRISPR-based therapeutics
- Cell-based therapies
- Neuropathway investigation
- DREADDS Experimentation
Its precision and control make it especially valuable when reproducibility and tissue preservation are critical to study success.
Improved Ergonomics for High-Throughput Studies
Large animal cohorts can require dozens, or even hundreds, of injections in a single study. A lightweight handheld syringe offers practical advantages during extended procedures:
- Reduced operator fatigue
- Faster procedural setup
- Greater maneuverability
- Improved consistency between injections
- Researchers can maintain precision while increasing throughput, helping accelerate preclinical studies without sacrificing data quality.
Supporting the Next Generation of Neuroscience and Ophthalmic Research
As neuroscience and ophthalmology continue advancing into increasingly sophisticated therapeutics, including gene editing, RNA therapies, targeted biologics, and regenerative medicine, demand for precise microvolume delivery continues to grow.
A handheld 5 µL NanoFil™ syringe provides researchers with the control, accuracy, and confidence needed to perform delicate brain and ocular injections while protecting valuable samples and minimizing tissue disruption.
For laboratories focused on retinal biology, gene therapy, glaucoma research, and ocular drug development, a handheld 5 µL NanoFil™ syringe is more than just a delivery device. It is a critical tool for producing high-quality, reproducible scientific results independently.
Be the First to Know
The new 5 µL, 25 µL, and 50 µL NanoFil™ syringes are almost here. Sign up today to receive priority notification when these highly anticipated syringe sizes become available early this summer.
