{"title":"Electrophysiology","description":"\u003ch1\u003e\u003cspan\u003eElectrophysiology\u003c\/span\u003e\u003c\/h1\u003e\n\u003cp\u003e\u003cspan\u003eElectrophysiology helps researchers investigate how electrical signals are generated, transmitted and regulated in cells and tissues. Whether you’re recording from a single cell or studying activity across a neural network, a dependable setup helps you capture and interpret those signals. \u003c\/span\u003e\u003cspan\u003eExplore amplifiers for patch clamp, intracellular and extracellular recordings; stimulators for delivering controlled electrical pulses; and stimulus isolators for delivering stimulation while keeping the stimulation circuit electrically separate from the recording setup. Browse the range to find components for building a new system or expanding an existing one.\u003c\/span\u003e\u003c\/p\u003e","products":[{"product_id":"74030-isolated-low-noise-bioamplifer-chassis","title":"Isolated, Low Noise Bioamplifer Chassis","description":"\u003c!-- section:details --\u003e\n\u003ch2\u003eChassis for the isolated, low noise bio-amplifer\u003c\/h2\u003e\r\n\u003cp\u003eSee what you need to know \u003ca href=\"\/blog\/post\/wpi-s-low-noise-amplifiers-outperform-cheap-imitations\"\u003ebefore you buy an amplifier\u003c\/a\u003e.\u003c\/p\u003e\r\n\u003ch2\u003eFeatures\u003c\/h2\u003e\r\n\u003cul\u003e\r\n\u003cli\u003eOrder a chassis and power supply enclosure (the item on this page)\u003c\/li\u003e\r\n\u003cli\u003eSelect up to 8 modules (\u003ca href=\"\/74020-isolated-low-noise-bioamplifier-single-channel-module\"\u003e\u003cstrong\u003eISO-DAM8A\u003c\/strong\u003e \u003c\/a\u003eor \u003ca href=\"\/bridge8-bridge8-transducer-amplifier-module\"\u003e\u003cstrong\u003eBRIDGE8\u003c\/strong\u003e\u003c\/a\u003e)\u003c\/li\u003e\r\n\u003cli\u003eOrder blank panels (\u003ca href=\"\/74050-isdb-blank-panels\"\u003e\u003cstrong\u003e74050\u003c\/strong\u003e\u003c\/a\u003e) to fill empty slots\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003ch2\u003eBenefits\u003c\/h2\u003e\r\n\u003cul\u003e\r\n\u003cli\u003eChassis accepts combination of bioamplifiers and transducer amplifiers\u003c\/li\u003e\r\n\u003cli\u003eFlexible channel count (1–8) allows expandability\u003c\/li\u003e\r\n\u003cli\u003eNotch filter targets AC line noise sources\u003c\/li\u003e\r\n\u003cli\u003eVariable gain output amplitude\u003c\/li\u003e\r\n\u003cli\u003eWide ±10V output range\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003ch2\u003eApplications \u003c\/h2\u003e\r\n\u003cul\u003e\r\n\u003cli\u003eAmplifying biopotentials using metal microelectrodes\u003c\/li\u003e\r\n\u003cli\u003eBrain slice field potentials\u003c\/li\u003e\r\n\u003cli\u003eEAG (Electroantennogram)\u003c\/li\u003e\r\n\u003cli\u003eERG (Electroretinogram)\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003cp\u003eThe \u003cstrong\u003eISO-DAM8A\u003c\/strong\u003e is a compact modular standard rack-mountable DC amplifier system. Each channel is electrically isolated from the others and from ground. No current can flow from the input terminals and electrodes. The instrument is intrinsically safe and cannot cause any electrical stimulus or shock to the preparation. In addition, ground loop noise is minimized.\u003c\/p\u003e\r\n\u003ch2\u003eFilters Included with the Amplifier\u003c\/h2\u003e\r\n\u003cp\u003eSystems can be purchased with one, two, three or up to eight preamplifier modules or mixed with \u003cstrong\u003eBridge8\u003c\/strong\u003e transducer amplifier modules. You can then select:\u003c\/p\u003e\r\n\u003cul\u003e\r\n\u003cli\u003eAn appropriate low pass filter setting, gain and offset on the channel amplifier panel.\u003c\/li\u003e\r\n\u003cli\u003eNotch filter added to reduce line frequency interference.\u003c\/li\u003e\r\n\u003cli\u003eOptional headstage preamplifier (10x gain) allows low noise extracellular (DC) recording with \u003cstrong\u003eIso-DAM8A\u003c\/strong\u003e and adds greater signal bandwidth than a shielded cable of the same length.\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003cp\u003eThe \u003cstrong\u003eIso-DAM8A\u003c\/strong\u003e amplifier and headstage configuration is optimally suited for use with our \u003ca href=\"\/products\/supplies-parts-accessories\/electrodes\/electrodes\"\u003emetal microelectrodes\u003c\/a\u003e and can be easily configured for many applications. Each amplifier channel has a coaxial (BNC) connector located on the rear panel.\u003c\/p\u003e\r\n\u003ch2\u003eConfiguring Your ISDB System\u003c\/h2\u003e\r\n\u003cp\u003eThe ISDB chassis (\u003ca href=\"\/74030-isolated-low-noise-bioamplifer-chassis\"\u003e\u003cstrong\u003e74030\u003c\/strong\u003e\u003c\/a\u003e) holds up to eight modules and includes a power supply. You may include any combination of \u003ca href=\"\/bridge8-bridge8-transducer-amplifier-module\"\u003e\u003cstrong\u003eBRIDGE8\u003c\/strong\u003e \u003c\/a\u003eTransducer Amplifier modules or ISO-DAM8A single channel modules (\u003ca href=\"\/74020-isolated-low-noise-bioamplifier-single-channel-module\"\u003e\u003cstrong\u003e74020\u003c\/strong\u003e\u003c\/a\u003e). If you choose fewer than eight modules, you need to order the ISDB blank panels (\u003ca href=\"\/74050-isdb-blank-panels\"\u003e\u003cstrong\u003e74050\u003c\/strong\u003e\u003c\/a\u003e) to fill the empty slots in the chassis. ISO-DAM8A bioampliers include an 8-pin DIN connector with shielded, unterminated 5' cable. Please specify line voltage when ordering.\u003c\/p\u003e\r\n\u003cp\u003eWhen configuring your ISDB system:\u003c\/p\u003e\r\n\u003cul\u003e\r\n\u003cli\u003eOrder a chassis and power supply enclosure (\u003ca href=\"\/74030-isolated-low-noise-bioamplifer-chassis\"\u003e\u003cstrong\u003e74030\u003c\/strong\u003e\u003c\/a\u003e)\u003c\/li\u003e\r\n\u003cli\u003eSelect up to 8 modules (\u003ca href=\"\/74020-isolated-low-noise-bioamplifier-single-channel-module\"\u003e\u003cstrong\u003eISO-DAM8A\u003c\/strong\u003e \u003c\/a\u003eor \u003ca href=\"\/bridge8-bridge8-transducer-amplifier-module\"\u003e\u003cstrong\u003eBRIDGE8\u003c\/strong\u003e\u003c\/a\u003e)\u003c\/li\u003e\r\n\u003cli\u003eOrder blank panels (\u003ca href=\"\/74050-isdb-blank-panels\"\u003e\u003cstrong\u003e74050\u003c\/strong\u003e\u003c\/a\u003e) to fill empty slots\u003c\/li\u003e\r\n\u003cli\u003eISO-DAM8A \u003ca href=\"\/74020-isolated-low-noise-bioamplifier-single-channel-module\"\u003e\u003cstrong\u003e74020\u003c\/strong\u003e \u003c\/a\u003eis a DC amplifier\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003cp\u003eComplete eight channel amplifier system with 74030 chassis showing eight \u003ca href=\"\/74020-isolated-low-noise-bioamplifier-single-channel-module\"\u003e74020\u003c\/a\u003e (ISODAM8A) modules installed\u003cbr\u003e*Also available for BRIDGE8 transducer amplifier modules and blank panels (74050).\u003c\/p\u003e\r\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0662\/7993\/1994\/files\/Iso-DAM8a-full_7f8b430e-57f7-43a1-a0bb-cc0a58b4b19f.jpg?v=1765943236\" alt=\"Iso-DAM8a\" width=\"500\" height=\"205\"\u003e\u003c\/p\u003e\r\n\u003cp\u003ePhoto illustrates a complete amplifier system and is shown with the 74030 chassis and eight ISO-DAM8A (74020)  amplifier modules.\u003c\/p\u003e\r\n\u003cp\u003e*The modules are sold separately.  \u003c\/p\u003e\n\u003c!-- \/section:details --\u003e\n\n\u003c!-- section:specifications --\u003e\n\u003ctable\u003e\r\n\u003ctbody\u003e\r\n\u003ctr bgcolor=\"#e4e4e4\"\u003e\r\n\u003ctd\u003ePower Source\u003c\/td\u003e\r\n\u003ctd\u003ePower Adapter 110-120V\/60Hz or 220-240\/50Hz\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd\u003eEnclosure Dimensions\u003c\/td\u003e\r\n\u003ctd\u003e7 x 17 x 9.2˝ (18 x 43 x 23 cm)\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr bgcolor=\"#e4e4e4\"\u003e\r\n\u003ctd\u003eShipping Weight\u003c\/td\u003e\r\n\u003ctd\u003e10–21 lb. (4.5–9.5 kg)\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003c\/tbody\u003e\r\n\u003c\/table\u003e\r\n\u003cp\u003e \u003c\/p\u003e\n\u003c!-- \/section:specifications --\u003e","brand":"World Precision Instruments","offers":[{"title":"Default Title","offer_id":42265635651674,"sku":"74030","price":2800.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/7993\/1994\/files\/isdb_e0309281-674f-41e9-b88a-cedf625e29be.jpg?v=1766393128"},{"product_id":"var-2273-constant-current-stimulus-isolator","title":"Constant Current Stimulus Isolator","description":"\u003c!-- section:details --\u003e\n\u003ch2\u003eAutomated bipolar pulsing for zero net charge on biological preparations\u003c\/h2\u003e\n\u003ch2\u003eFeatures\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eConstant current\u003c\/li\u003e\n\u003cli\u003eUnipolar and bipolar stimulation modes\u003c\/li\u003e\n\u003cli\u003eBuilt-in non-compliance alarm\u003c\/li\u003e\n\u003cli\u003eInput is optically isolated\u003c\/li\u003e\n\u003cli\u003eStandard TTL triggering\u003c\/li\u003e\n\u003cli\u003eDC test mode\u003c\/li\u003e\n\u003cli\u003ePowered by 9 V alkaline or rechargeable batteries\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eOptions\u003c\/h2\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr style=\"background-color: #0081c2;\"\u003e\n\u003ctd\u003e\u003cstrong\u003e\u003cspan style=\"color: #ffffff;\"\u003ePart #\u003c\/span\u003e\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e\u003cspan style=\"color: #ffffff;\"\u003eDescription\u003c\/span\u003e\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e\u003cspan style=\"color: #ffffff;\"\u003eBattery Type\u003c\/span\u003e\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003cstrong\u003e\u003cspan style=\"color: #ffffff;\"\u003eIncludes Charger\u003c\/span\u003e\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #e4e4e4;\"\u003e\n\u003ctd\u003e\u003cstrong\u003eA365RC\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eA365R with an A362 Battery Charger\u003c\/td\u003e\n\u003ctd\u003eRechargeable Battery\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eYes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003cstrong\u003eSYS-A365R\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eHigh Voltage Isolator, Bipolar\u003c\/td\u003e\n\u003ctd\u003eRechargeable Battery\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eNo\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #e4e4e4;\"\u003e\n\u003ctd\u003e\u003cstrong\u003eSYS-A365D\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd\u003eHigh Voltage Isolator, Bipolar\u003c\/td\u003e\n\u003ctd\u003eAlkaline Batteries\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e_\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eBenefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eCompliance voltage is 100V or better\u003c\/li\u003e\n\u003cli\u003eBipolar mode auto generates alternating positive and negative pulses from TTL input\u003c\/li\u003e\n\u003cli\u003eTest mode simplifies performance verification\u003c\/li\u003e\n\u003cli\u003eOptical isolation enhances safety of the preparation and reduces noise susceptibility\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eApplications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eElectrophysiology\u003c\/li\u003e\n\u003cli\u003eBrain slice stimulation\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eIn vivo\u003c\/em\u003e brain and CNS stimulation\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eActivated by conventional logic-level commands, Model \u003cstrong\u003eA365\u003c\/strong\u003e can be gated by any pulse generator, stimulator or computer output with automated bipolar pulsing for zero net charge on biological preparations.\u003c\/p\u003e\n\u003ch2\u003eDual tone audible alarms\u003c\/h2\u003e\n\u003cp\u003eA tone sounds when an open electrode circuit is detected or when system compliance is reached. A second optional tone sounds when a signal is applied to the input. A test switch is also provided to check battery charge.\u003c\/p\u003e\n\u003ch2\u003eCurrent delivery up to 10 mA at more than 100V\u003c\/h2\u003e\n\u003cp\u003eStimulus currents are set using a three-digit control knob and a three-position range switch. Output current tracks control set­tings to better than 1%. Output current is load independent, and voltage suf­fi­cient to push the desired current through the load is automatically de­vel­oped, sub­ject only to compliance limits. Model \u003cstrong\u003eA360LA\u003c\/strong\u003e produces up to 10 mA current, in three ranges, at more than 100 V compliance.\u003c\/p\u003e\n\u003ch2\u003eBipolar Output Polarity\u003c\/h2\u003e\n\u003cp\u003eOutput polarity is determined by a push switch on the front panel. Bipolar current is toggled by the command waveform, setting al­ter­nat­ing pulses as positive or negative.\u003c\/p\u003e\n\u003ch2\u003ePower\u003c\/h2\u003e\n\u003cp\u003eThis\u003cstrong\u003e\u003ca href=\"\/index.php?src=directory\u0026amp;view=products\u0026amp;srctype=detail\u0026amp;refno=2273\u0026amp;category=Physiology\"\u003e \u003c\/a\u003eA365RC\u003c\/strong\u003e Stimulus Isolator includes both the \u003cstrong\u003eA365R\u003c\/strong\u003e Stimulus Isolator and the \u003cstrong\u003eA362\u003c\/strong\u003e battery charger.The rechargeable \u003cstrong\u003eA365R\u003c\/strong\u003e is supplied with a nickel metal hydride battery stack. The \u003ca href=\"\/sys-a362-a362-battery-charger\"\u003e\u003cstrong\u003eA362\u003c\/strong\u003e Battery Charger\u003c\/a\u003e is required with the \u003cstrong\u003eA365R\u003c\/strong\u003e. \u003c\/p\u003e\n\u003cp\u003e NOTE: Not intended for human use.\u003c\/p\u003e\n\u003c!-- \/section:details --\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003c!-- section:resources --\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0662\/7993\/1994\/files\/A365_IMs.pdf\" target=\"_self\"\u003eA365 Instruction Manual\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003c!-- \/section:resources --\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003c!-- section:specifications --\u003e\n\u003ctable cellpadding=\"2\" cellspacing=\"0\" border=\"1\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eOUTPUT WAVEFORM\u003c\/td\u003e\n\u003ctd\u003eDC or current pulse\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\n\u003ctd\u003eOUTPUT CURRENT RANGES\u003c\/td\u003e\n\u003ctd\u003e0.1, 1.0, and 10 mA\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCURRENT AMPLITUDE ERROR\u003c\/td\u003e\n\u003ctd\u003e0.5% of full scale, max.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\n\u003ctd\u003eCURRENT RESOLUTION\u003c\/td\u003e\n\u003ctd\u003e0.1% of full scale, typical\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOUTPUT LOAD VOLTAGE EXCURSION (COMPLIANCE)\u003c\/td\u003e\n\u003ctd\u003e100 V\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\n\u003ctd\u003eEXTERNAL COMMAND THRESHOLD\u003c\/td\u003e\n\u003ctd\u003e5 V at 3 mA, min. 10 V, max.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTRIGGER THRESHOLD\u003c\/td\u003e\n\u003ctd\u003e2.0 V at 0.5 mA\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOUTPUT POLARITY\u003c\/td\u003e\n\u003ctd\u003eReversible, manual switch or automatic\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\n\u003ctd\u003eCURRENT RISE TIME \u0026amp; DELAY\u003c\/td\u003e\n\u003ctd\u003e6 μs, typical (1 KΩ load)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCURRENT FALL TIME \u0026amp; DELAY\u003c\/td\u003e\n\u003ctd\u003e10 μs, typical (1 KΩ load)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\n\u003ctd\u003eOUTPUT TO GROUND RESISTANCE\u003c\/td\u003e\n\u003ctd\u003e10\u003csup\u003e12 \u003c\/sup\u003eΩ\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOPTOCOUPLER\u003c\/td\u003e\n\u003ctd\u003e2500 V, rated min. breakdown voltage\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\n\u003ctd\u003ePOWER: Model A365D (dry cell)\u003c\/td\u003e\n\u003ctd\u003e16 alkaline 9 V batteries, included\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePOWER: Model A365R (rechargeable)\u003c\/td\u003e\n\u003ctd\u003e16 rechargeable NiMH 9 V batteries included\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\n\u003ctd\u003eDIMENSIONS\u003c\/td\u003e\n\u003ctd\u003e8.5 x 3.5 x 5 in. (22 x 9 x 12 cm)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eSHIPPING WEIGHT\u003c\/td\u003e\n\u003ctd\u003e4 lb. (1.8 kg)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c!-- \/section:specifications --\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003c!-- section:references --\u003e\n\u003cp\u003e\u003cb\u003eYavich, L., Tanila, H., Vepsäläinen, S., \u0026amp; Jäkälä, P. (n.d.).\u003c\/b\u003e Neurobiology of Disease Role of ␣-Synuclein in Presynaptic Dopamine Recruitment. \u003ca href=\"https:\/\/doi.org\/10.1523\/JNEUROSCI.2559-04.2004\"\u003ehttps:\/\/doi.org\/10.1523\/JNEUROSCI.2559-04.2004\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eIremonger, K. J., Anderson, T. R., Hu, B., \u0026amp; Kiss, Z. H. T. (n.d.).\u003c\/b\u003e Cellular Mechanisms Preventing Sustained Activation of Cortex During Subcortical High-Frequency Stimulation. \u003ca href=\"https:\/\/doi.org\/10.1152\/jn.00105.2006\"\u003ehttps:\/\/doi.org\/10.1152\/jn.00105.2006\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eRowland, N. C., \u0026amp; Jaeger, D. (n.d.).\u003c\/b\u003e Responses to Tactile Stimulation in Deep Cerebellar Nucleus Neurons Result From Recurrent Activation in Multiple Pathways. \u003ca href=\"https:\/\/doi.org\/10.1152\/jn.01100.2007\"\u003ehttps:\/\/doi.org\/10.1152\/jn.01100.2007\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eD ’ambrosio, R., Gordon, D. S., Winn, H. R., ’ambrosio, D., Raimondo, D. S., Gordon, H., \u0026amp; Richard, W. (n.d.).\u003c\/b\u003e Differential Role of KIR Channel and Na ϩ \/K ϩ -Pump in the Regulation of Extracellular K ϩ in Rat Hippocampus. \u003ca href=\"https:\/\/doi.org\/10.1152\/jn.00240.2001\"\u003ehttps:\/\/doi.org\/10.1152\/jn.00240.2001\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eHuda, R., Mccrimmon, D. R., \u0026amp; Martina, M. (n.d.).\u003c\/b\u003e pH modulation of glial glutamate transporters regulates synaptic transmission in the nucleus of the solitary tract.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eChen, Y., Beffert, U., Ertunc, M., Tang, T.-S., Kavalali, E. T., Bezprozvanny, I., \u0026amp; Herz, J. (n.d.).\u003c\/b\u003e Development\/Plasticity\/Repair Reelin Modulates NMDA Receptor Activity in Cortical Neurons. \u003ca href=\"https:\/\/doi.org\/10.1523\/JNEUROSCI.1951-05.2005\"\u003ehttps:\/\/doi.org\/10.1523\/JNEUROSCI.1951-05.2005\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eD ’ambrosio, R., Wenzel, J., Schwartzkroin, P. A., Mckhann Ii, G. M., \u0026amp; Janigro, D. (n.d.).\u003c\/b\u003e Functional Specialization and Topographic Segregation of Hippocampal Astrocytes.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eD ’ambrosio, R., Maris, D. O., Grady, M. S., Winn, H. R., \u0026amp; Janigro, D. (n.d.).\u003c\/b\u003e Impaired K ؉ Homeostasis and Altered Electrophysiological Properties of Post-Traumatic Hippocampal Glia.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eJi, H., \u0026amp; Shepard, P. D. (n.d.).\u003c\/b\u003e Behavioral\/Systems\/Cognitive Lateral Habenula Stimulation Inhibits Rat Midbrain Dopamine Neurons through a GABA A Receptor-Mediated Mechanism. \u003ca href=\"https:\/\/doi.org\/10.1523\/JNEUROSCI.0958-07.2007\"\u003ehttps:\/\/doi.org\/10.1523\/JNEUROSCI.0958-07.2007\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eLee, E., Hong, J., Park, Y.-G., Chae, S., Kim, Y., \u0026amp; Kim, D. (2015).\u003c\/b\u003e Left brain cortical activity modulates stress effects on social behavior. \u003ci\u003eScientific Reports\u003c\/i\u003e, \u003ci\u003e5\u003c\/i\u003e, 13342. \u003ca href=\"https:\/\/doi.org\/10.1038\/srep13342\"\u003ehttps:\/\/doi.org\/10.1038\/srep13342\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eGindrat, A.-D., Quairiaux, C., Britz, J., Brunet, D., Lanz, F., Michel, C. M., \u0026amp; Rouiller, E. M. (2015).\u003c\/b\u003e Whole-scalp EEG mapping of somatosensory evoked potentials in macaque monkeys. \u003ci\u003eBrain Structure \u0026amp; Function\u003c\/i\u003e, \u003ci\u003e220\u003c\/i\u003e(4), 2121–2142. \u003ca href=\"https:\/\/doi.org\/10.1007\/s00429-014-0776-y\"\u003ehttps:\/\/doi.org\/10.1007\/s00429-014-0776-y\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eAvila, I., \u0026amp; Lin, S.-C. (2014).\u003c\/b\u003e Motivational Salience Signal in the Basal Forebrain Is Coupled with Faster and More Precise Decision Speed. \u003ci\u003ePLoS Biology\u003c\/i\u003e, \u003ci\u003e12\u003c\/i\u003e(3), e1001811. \u003ca href=\"https:\/\/doi.org\/10.1371\/journal.pbio.1001811\"\u003ehttps:\/\/doi.org\/10.1371\/journal.pbio.1001811\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eNguyen, D. P., \u0026amp; Lin, S.-C. (2014).\u003c\/b\u003e A frontal cortex event-related potential driven by the basal forebrain. \u003ci\u003eELife\u003c\/i\u003e, \u003ci\u003e3\u003c\/i\u003e, e02148. Retrieved from \u003ca rel=\"noopener\" href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3974155\/\" target=\"_blank\"\u003ehttps:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3974155\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eHerrera, C., Directores, R., Panetsos, F., Carlos, P., \u0026amp; Trueba, A. (2014).\u003c\/b\u003e TESIS DOCTORAL Efectos de la estimulación artificial de un nervio periférico seccionado sobre la vía somatosensorial desaferentizada de la rata.\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eYounce, J. R., Albaugh, D. L., \u0026amp; Shih, Y.-Y. I. (2014).\u003c\/b\u003e Deep Brain Stimulation with Simultaneous fMRI in Rodents. \u003ci\u003eJournal of Visualized Experiments\u003c\/i\u003e, (84), e51271–e51271. \u003ca href=\"https:\/\/doi.org\/10.3791\/51271\"\u003ehttps:\/\/doi.org\/10.3791\/51271\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eOulad Ben Taib, N., \u0026amp; Manto, M. (2013).\u003c\/b\u003e Trains of Epidural DC Stimulation of the Cerebellum Tune Corticomotor Excitability. \u003ci\u003eNeural Plasticity\u003c\/i\u003e, \u003ci\u003e2013\u003c\/i\u003e(10), 1–12. \u003ca href=\"https:\/\/doi.org\/10.1155\/2013\/613197\"\u003ehttps:\/\/doi.org\/10.1155\/2013\/613197\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eSyvänen, S., Russmann, V., Verbeek, J., Eriksson, J., Labots, M., Zellinger, C., … Potschka, H. (2013).\u003c\/b\u003e [11C]quinidine and [11C]laniquidar PET imaging in a chronic rodent epilepsy model: Impact of epilepsy and drug-responsiveness. \u003ci\u003eNuclear Medicine and Biology\u003c\/i\u003e, \u003ci\u003e40\u003c\/i\u003e(6), 764–775. \u003ca href=\"https:\/\/doi.org\/10.1016\/j.nucmedbio.2013.05.008\"\u003ehttps:\/\/doi.org\/10.1016\/j.nucmedbio.2013.05.008\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eSchroder, E. A., Lefta, M., Zhang, X., Bartos, D. C., Feng, H.-Z., Zhao, Y., … Delisle, B. P. (2013).\u003c\/b\u003e The cardiomyocyte molecular clock, regulation of Scn5a, and arrhythmia susceptibility. \u003ci\u003eAmerican Journal of Physiology. Cell Physiology\u003c\/i\u003e, \u003ci\u003e304\u003c\/i\u003e(10), C954-65. \u003ca href=\"https:\/\/doi.org\/10.1152\/ajpcell.00383.2012\"\u003ehttps:\/\/doi.org\/10.1152\/ajpcell.00383.2012\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eSchmuckermair, C., Gaburro, S., Sah, A., Landgraf, R., Sartori, S. B., \u0026amp; Singewald, N. (2013).\u003c\/b\u003e Behavioral and neurobiological effects of deep brain stimulation in a mouse model of high anxiety- and depression-like behavior. \u003ci\u003eNeuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology\u003c\/i\u003e, \u003ci\u003e38\u003c\/i\u003e(7), 1234–1244. \u003ca href=\"https:\/\/doi.org\/10.1038\/npp.2013.21\"\u003ehttps:\/\/doi.org\/10.1038\/npp.2013.21\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eDalby-Brown, W., Jessen, C., Hougaard, C., Jensen, M. L., Jacobsen, T. A., Nielsen, K. S., … Jørgensen, S. (2013).\u003c\/b\u003e Characterization of a novel high-potency positive modulator of Kv7 channels. \u003ci\u003eEuropean Journal of Pharmacology\u003c\/i\u003e, \u003ci\u003e709\u003c\/i\u003e(1–3), 52–63. \u003ca href=\"https:\/\/doi.org\/10.1016\/j.ejphar.2013.03.039\"\u003ehttps:\/\/doi.org\/10.1016\/j.ejphar.2013.03.039\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eLicko, T., Seeger, N., Zellinger, C., Russmann, V., Matagne, A., \u0026amp; Potschka, H. (2013). \u003c\/b\u003eLacosamide treatment following status epilepticus attenuates neuronal cell loss and alterations in hippocampal neurogenesis in a rat electrical status epilepticus model. \u003ci\u003eEpilepsia\u003c\/i\u003e, \u003ci\u003e54\u003c\/i\u003e(7), 1176–1185. \u003ca href=\"https:\/\/doi.org\/10.1111\/epi.12196\"\u003ehttps:\/\/doi.org\/10.1111\/epi.12196\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eAtherton, J. F., Menard, A., Urbain, N., \u0026amp; Bevan, M. D. (2013).\u003c\/b\u003e Short-term depression of external globus pallidus-subthalamic nucleus synaptic transmission and implications for patterning subthalamic activity. \u003ci\u003eThe Journal of Neuroscience : The Official Journal of the Society for Neuroscience\u003c\/i\u003e, \u003ci\u003e33\u003c\/i\u003e(17), 7130–7144. \u003ca href=\"https:\/\/doi.org\/10.1523\/JNEUROSCI.3576-12.2013\"\u003ehttps:\/\/doi.org\/10.1523\/JNEUROSCI.3576-12.2013\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eSaha, D., Leong, K., Katta, N., \u0026amp; Raman, B. (2013).\u003c\/b\u003e Multi-unit Recording Methods to Characterize Neural Activity in the Locust (\u0026amp;lt;em\u0026amp;gt;Schistocerca Americana\u0026amp;lt;\/em\u0026amp;gt;) Olfactory Circuits. \u003ci\u003eJournal of Visualized Experiments\u003c\/i\u003e, (71), e50139–e50139. \u003ca href=\"https:\/\/doi.org\/10.3791\/50139\"\u003ehttps:\/\/doi.org\/10.3791\/50139\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eHuda, R., McCrimmon, D. R., \u0026amp; Martina, M. (2013).\u003c\/b\u003e pH modulation of glial glutamate transporters regulates synaptic transmission in the nucleus of the solitary tract. \u003ci\u003eJournal of Neurophysiology\u003c\/i\u003e, \u003ci\u003e110\u003c\/i\u003e(2), 368–377. \u003ca href=\"https:\/\/doi.org\/10.1152\/jn.01074.2012\"\u003ehttps:\/\/doi.org\/10.1152\/jn.01074.2012\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eSonner, P. M., \u0026amp; Ladle, D. R. (2013).\u003c\/b\u003e Early postnatal development of GABAergic presynaptic inhibition of Ia proprioceptive afferent connections in mouse spinal cord. \u003ci\u003eJournal of Neurophysiology\u003c\/i\u003e, \u003ci\u003e109\u003c\/i\u003e(8), 2118–2128. \u003ca href=\"https:\/\/doi.org\/10.1152\/jn.00783.2012\"\u003ehttps:\/\/doi.org\/10.1152\/jn.00783.2012\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eZhu, Z., Sierra, A., Burnett, C. M.-L. L., Chen, B., Subbotina, E., Koganti, S. R. K., … Zingman, L. V. (2013).\u003c\/b\u003e Sarcolemmal ATP-sensitive potassium channels modulate skeletal muscle function under low-intensity workloads. \u003ci\u003eThe Journal of General Physiology\u003c\/i\u003e, \u003ci\u003e143\u003c\/i\u003e(1), 119–134. \u003ca href=\"https:\/\/doi.org\/10.1085\/jgp.201311063\"\u003ehttps:\/\/doi.org\/10.1085\/jgp.201311063\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eBrenowitz, S. D., \u0026amp; Regehr, W. G. (2012).\u003c\/b\u003e Presynaptic imaging of projection fibers by in vivo injection of dextran-conjugated calcium indicators. \u003ci\u003eCold Spring Harbor Protocols\u003c\/i\u003e, \u003ci\u003e2012\u003c\/i\u003e(4), 465–471. \u003ca href=\"https:\/\/doi.org\/10.1101\/pdb.prot068551\"\u003ehttps:\/\/doi.org\/10.1101\/pdb.prot068551\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eLi, W., Janardhan, A. H., Fedorov, V. V, Sha, Q., Schuessler, R. B., \u0026amp; Efimov, I. R. (2011).\u003c\/b\u003e Low-energy multistage atrial defibrillation therapy terminates atrial fibrillation with less energy than a single shock. \u003ci\u003eCirculation. Arrhythmia and Electrophysiology\u003c\/i\u003e, \u003ci\u003e4\u003c\/i\u003e(6), 917–925. \u003ca href=\"https:\/\/doi.org\/10.1161\/CIRCEP.111.965830\"\u003ehttps:\/\/doi.org\/10.1161\/CIRCEP.111.965830\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eMathis, D. M., Furman, J. L., \u0026amp; Norris, C. M. (2011).\u003c\/b\u003e Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology. \u003ci\u003eJournal of Visualized Experiments\u003c\/i\u003e, (49), e2330–e2330. \u003ca href=\"https:\/\/doi.org\/10.3791\/2330\"\u003ehttps:\/\/doi.org\/10.3791\/2330\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eManto, M. U., Hampe, C. S., Rogemond, V., \u0026amp; Honnorat, J. (2011).\u003c\/b\u003e Respective implications of glutamate decarboxylase antibodies in stiff person syndrome and cerebellar ataxia. \u003ci\u003eOrphanet Journal of Rare Diseases\u003c\/i\u003e, \u003ci\u003e6\u003c\/i\u003e(1), 3. \u003ca href=\"https:\/\/doi.org\/10.1186\/1750-1172-6-3\"\u003ehttps:\/\/doi.org\/10.1186\/1750-1172-6-3\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eKim, J., Woo, J., Park, Y.-G., Chae, S., Jo, S., Choi, J. W., … Kim, D. (2011).\u003c\/b\u003e Thalamic T-type Ca\u003csup\u003e2\u003c\/sup\u003e+ channels mediate frontal lobe dysfunctions caused by a hypoxia-like damage in the prefrontal cortex. \u003ci\u003eThe Journal of Neuroscience : The Official Journal of the Society for Neuroscience\u003c\/i\u003e, \u003ci\u003e31\u003c\/i\u003e(11), 4063–4073. \u003ca href=\"https:\/\/doi.org\/10.1523\/JNEUROSCI.4493-10.2011\"\u003ehttps:\/\/doi.org\/10.1523\/JNEUROSCI.4493-10.2011\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eSeo, J. H., Jang, I. K., Kim, H., Yang, M. S., Lee, J. E., Kim, H. E., … Cho, S.-R. (2011).\u003c\/b\u003e Early Immunomodulation by Intravenously Transplanted Mesenchymal Stem Cells Promotes Functional Recovery in Spinal Cord Injured Rats. \u003ci\u003eCell Medicine\u003c\/i\u003e, \u003ci\u003e2\u003c\/i\u003e(2), 55–67. \u003ca href=\"https:\/\/doi.org\/10.3727\/215517911X582788\"\u003ehttps:\/\/doi.org\/10.3727\/215517911X582788\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003ePelkonen, A., Hiltunen, M., Kiianmaa, K., \u0026amp; Yavich, L. (2010).\u003c\/b\u003e Stimulated dopamine overflow and alpha-synuclein expression in the nucleus accumbens core distinguish rats bred for differential ethanol preference. \u003ci\u003eJournal of Neurochemistry\u003c\/i\u003e, \u003ci\u003e114\u003c\/i\u003e(4), 1168–1176. \u003ca href=\"https:\/\/doi.org\/10.1111\/j.1471-4159.2010.06844.x\"\u003ehttps:\/\/doi.org\/10.1111\/j.1471-4159.2010.06844.x\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eFoust, A. J., Schei, J. L., Rojas, M. J., \u0026amp; Rector, D. M. (2008).\u003c\/b\u003e In vitro and in vivo noise analysis for optical neural recording. \u003ci\u003eJournal of Biomedical Optics\u003c\/i\u003e, \u003ci\u003e13\u003c\/i\u003e(4), 044038. \u003ca href=\"https:\/\/doi.org\/10.1117\/1.2952295\"\u003ehttps:\/\/doi.org\/10.1117\/1.2952295\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eSchei, J. L., McCluskey, M. D., Foust, A. J., Yao, X.-C., \u0026amp; Rector, D. M. (2008). \u003c\/b\u003eAction potential propagation imaged with high temporal resolution near-infrared video microscopy and polarized light. \u003ci\u003eNeuroImage\u003c\/i\u003e, \u003ci\u003e40\u003c\/i\u003e(3), 1034–1043. \u003ca href=\"https:\/\/doi.org\/10.1016\/j.neuroimage.2007.12.055\"\u003ehttps:\/\/doi.org\/10.1016\/j.neuroimage.2007.12.055\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eFoust, A. J., \u0026amp; Rector, D. M. (2007). \u003c\/b\u003eOptically teasing apart neural swelling and depolarization. \u003ci\u003eNeuroscience\u003c\/i\u003e, \u003ci\u003e145\u003c\/i\u003e(3), 887–899. \u003ca href=\"https:\/\/doi.org\/10.1016\/j.neuroscience.2006.12.068\"\u003ehttps:\/\/doi.org\/10.1016\/j.neuroscience.2006.12.068\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eJi, H., \u0026amp; Shepard, P. D. (2007).\u003c\/b\u003e Lateral habenula stimulation inhibits rat midbrain dopamine neurons through a GABA(A) receptor-mediated mechanism. \u003ci\u003eThe Journal of Neuroscience : The Official Journal of the Society for Neuroscience\u003c\/i\u003e, \u003ci\u003e27\u003c\/i\u003e(26), 6923–6930. \u003ca href=\"https:\/\/doi.org\/10.1523\/JNEUROSCI.0958-07.2007\"\u003ehttps:\/\/doi.org\/10.1523\/JNEUROSCI.0958-07.2007\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eLee, B. H., Lee, K. H., Yoon, D. H., Kim, U. J., Hwang, Y. S., Park, S. K., … Jahng, T. (2005).\u003c\/b\u003e Effects of methylprednisolone on the neural conduction of the motor evoked potentials in spinal cord injured rats. \u003ci\u003eJournal of Korean Medical Science\u003c\/i\u003e, \u003ci\u003e20\u003c\/i\u003e(1), 132–138. \u003ca href=\"https:\/\/doi.org\/10.3346\/jkms.2005.20.1.132\"\u003ehttps:\/\/doi.org\/10.3346\/jkms.2005.20.1.132\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eAnderson, T., Hu, B., Pittman, Q., \u0026amp; Kiss, Z. H. T. (2004).\u003c\/b\u003e Mechanisms of deep brain stimulation: an intracellular study in rat thalamus. \u003ci\u003eThe Journal of Physiology\u003c\/i\u003e, \u003ci\u003e559\u003c\/i\u003e(1), 301–313. \u003ca href=\"https:\/\/doi.org\/10.1113\/jphysiol.2004.064998\"\u003ehttps:\/\/doi.org\/10.1113\/jphysiol.2004.064998\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eSokolow, S., Manto, M., Gailly, P., Molgó, J., Vandebrouck, C., Vanderwinden, J.-M., … Schurmans, S. (2004).\u003c\/b\u003e Impaired neuromuscular transmission and skeletal muscle fiber necrosis in mice lacking Na\/Ca exchanger 3. \u003ci\u003eJournal of Clinical Investigation\u003c\/i\u003e, \u003ci\u003e113\u003c\/i\u003e(2), 265–273. \u003ca href=\"https:\/\/doi.org\/10.1172\/JCI18688\"\u003ehttps:\/\/doi.org\/10.1172\/JCI18688\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eD’Ambrosio, R., Fairbanks, J. P., Fender, J. S., Born, D. E., Doyle, D. L., \u0026amp; Miller, J. W. (2004). \u003c\/b\u003ePost-traumatic epilepsy following fluid percussion injury in the rat. \u003ci\u003eBrain : A Journal of Neurology\u003c\/i\u003e, \u003ci\u003e127\u003c\/i\u003e(Pt 2), 304–314. \u003ca href=\"https:\/\/doi.org\/10.1093\/brain\/awh038\"\u003ehttps:\/\/doi.org\/10.1093\/brain\/awh038\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eShaw, B. K., \u0026amp; Kennedy, G. G. (2002).\u003c\/b\u003e Evidence for species differences in the pattern of androgen receptor distribution in relation to species differences in an androgen-dependent behavior. \u003ci\u003eJournal of Neurobiology\u003c\/i\u003e, \u003ci\u003e52\u003c\/i\u003e(3), 203–220. \u003ca href=\"https:\/\/doi.org\/10.1002\/neu.10079\"\u003ehttps:\/\/doi.org\/10.1002\/neu.10079\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eYavich, L., \u0026amp; Tiihonen, J. (2000).\u003c\/b\u003e Ethanol modulates evoked dopamine release in mouse nucleus accumbens: dependence on social stress and dose. \u003ci\u003eEuropean Journal of Pharmacology\u003c\/i\u003e, \u003ci\u003e401\u003c\/i\u003e(3), 365–373. Retrieved from \u003ca href=\"http:\/\/www.safetylit.org\/citations\/index.php?fuseaction=citations.viewdetails\u0026amp;citationIds%5B%5D=citjournalarticle_271069_38\"\u003ehttp:\/\/www.safetylit.org\/citations\/index.php?fuseaction=citations.viewdetails\u0026amp;citationIds%5B%5D=citjournalarticle_271069_38\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cb\u003eKnisley, S. B., Trayanova, N., \u0026amp; Aguel, F. (1999).\u003c\/b\u003e Roles of Electric Field and Fiber Structure in Cardiac Electric Stimulation. \u003ci\u003eBiophysical Journal\u003c\/i\u003e, \u003ci\u003e77\u003c\/i\u003e(3), 1404–1417. \u003ca href=\"https:\/\/doi.org\/10.1016\/S0006-3495(99)76989-4\"\u003ehttps:\/\/doi.org\/10.1016\/S0006-3495(99)76989-4\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003c!-- \/section:references --\u003e","brand":"World Precision Instruments","offers":[{"title":"Alkaline","offer_id":42266068615258,"sku":"SYS-A365D","price":1800.0,"currency_code":"USD","in_stock":true},{"title":"Rechargeable","offer_id":42266068582490,"sku":"SYS-A365R","price":2300.0,"currency_code":"USD","in_stock":true},{"title":"Rechargeable with Charger","offer_id":42266068648026,"sku":"A365RC","price":2700.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/7993\/1994\/files\/a365_1_fc747f0d-6742-4e53-b046-ddaebb5c1dcc.jpg?v=1766396620"},{"product_id":"sys-a382-battery-charger","title":"Battery Charger","description":"\u003c!-- section:details --\u003e\n\u003ch2\u003eFeatures\u003c\/h2\u003e\r\n\u003cul\u003e\r\n\u003cli\u003eInnovative 3-step charger employs fast, medium, and trickle charges\u003c\/li\u003e\r\n\u003cli\u003eCharges at a safe, low current, greatly extending battery life\u003c\/li\u003e\r\n\u003cli\u003eFor use only with batteries in A385 Stimulus Isolator\u003c\/li\u003e\r\n\u003c\/ul\u003e\n\u003c!-- \/section:details --\u003e\n\n\u003c!-- section:resources --\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0662\/7993\/1994\/files\/A382-IM.pdf\"\u003eA382 Instruction Manual\u003c\/a\u003e\u003c\/p\u003e\n\u003c!-- \/section:resources --\u003e\n\n\u003c!-- section:specifications --\u003e\n\u003ctable border=\"1\" cellspacing=\"0\" cellpadding=\"2\"\u003e\r\n\u003ctbody\u003e\r\n\u003ctr\u003e\r\n\u003ctd\u003ePOWER\u003c\/td\u003e\r\n\u003ctd\u003e95-135 V or 220-240 V, 50\/60 Hz\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\r\n\u003ctd\u003eDIMENSIONS\u003c\/td\u003e\r\n\u003ctd\u003e8.5 x 3.5 x 5 in (22 x 9 x 12 cm)\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd\u003eSHIPPING WEIGHT\u003c\/td\u003e\r\n\u003ctd\u003e5 lb (2.3 kg)\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003c\/tbody\u003e\r\n\u003c\/table\u003e\n\u003c!-- \/section:specifications --\u003e","brand":"World Precision Instruments","offers":[{"title":"Default Title","offer_id":42266239172698,"sku":"SYS-A382","price":975.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/7993\/1994\/files\/a382-front_e2948864-4042-4264-8ad1-ce6b91ddd557.jpg?v=1766399584"},{"product_id":"var-su-dpatch-dpatch-system","title":"dPatch system","description":"\u003c!-- section:details --\u003e\n\u003ch2\u003eOptions\u003c\/h2\u003e\n\u003ctable width=\"100%\" style=\"width: 100%;\" class=\"product-table\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd style=\"text-align: center; width: 15.4776%;\"\u003e\u003cstrong\u003eOrder code\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center; width: 38.4522%;\"\u003e\u003cstrong\u003eDescription\u003c\/strong\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center; width: 46.0701%;\"\u003e\u003cstrong\u003eDetails\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 15.4776%;\"\u003eSU-DPATCH\u003c\/td\u003e\n\u003ctd style=\"width: 38.4522%;\"\u003edPatch system with one headstage and preamp\u003c\/td\u003e\n\u003ctd style=\"width: 46.0701%;\"\u003eIncludes: dPatch system with one headstage and preamplifier, 505671 pipette holder, model cell, screw terminal for digital outputs, rack mounting hardware; SutterPatch® software suite with Igor Pro license\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"width: 15.4776%;\"\u003eSU-DPATCH-2\u003c\/td\u003e\n\u003ctd style=\"width: 38.4522%;\"\u003edPatch system with two headstages and preamp\u003c\/td\u003e\n\u003ctd style=\"width: 46.0701%;\"\u003eIncludes: dPatch system with two headstages and preamplifiers, two 505671 pipette holders, two model cells, screw terminals for digital outputs, rack mounting hardware; SutterPatch® software suite with Igor Pro license\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003ch2\u003eLEGENDARY SUPPORT\u003c\/h2\u003e\n\u003cp\u003eSutter has a long history of standing by our products and continually improving them. While other amplifiers on the market haven't been updated in 20 years, the dPatch will continue to be developed and supported WELL into the future. All of our products are built in the USA, and we offer free support should you need any help.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003e5 MHz SAMPLING RATE, UP TO 22-BIT RESOLUTION\u003c\/h2\u003e\n\u003cp\u003eOne unique feature with dPatch is the headstage data sampling system. Each headstage is continually sampled at 5 MHz. Output filtering has thirteen settings between 100 Hz and 1 MHz. A resolution of 18 bits is achieved at 1 MHz. For lower filter settings, automatic downsampling increases resolution while optimizing data rates. At a bandwidth setting of 1 kHz, the dPatch system provides a signal resolution of better than 22 bits.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eNO ACTIVE COOLING REQUIRED\u003c\/h2\u003e\n\u003cp\u003eActive cooling causes numerous problems that actually create more \"noise\" in the long run. Active cooling in amplifier headstages use Peltier cells, which cool the electronics for slightly better performance, but generate considerable heat on the opposite side of the cell. The heat generated causes thermal drift which makes it almost impossible to stay patched while doing single-channel work. This is THE MOST COMMON source of what users perceive as \"manipulator drift\". As a company that makes micromanipulators, we are highly sensitive to the performance of the system within a complete electrophysiology rig.\u003c\/p\u003e\n\u003cp\u003eActive cooling can help get a slightly better noise specification on paper, but in the real world the disadvantages far outweigh the slight gain in specsmanship. One of the development goals of the dPatch headstage was achieving a comparable noise performance at room temperature, without the need for a cooled headstage. In the two resistive feedback modes, the dPatch amplifier is even quieter than any of the competitor systems. In addition, the limited life expectancy of Peltier elements causes reliability concerns that we found unacceptable.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eBUILT-IN DATA ACQUISITION SYSTEM MEANS NO THIRD-PARTY COMPUTER INTERFACE\u003c\/h2\u003e\n\u003cp\u003eUsing a multiplexer-free design, the dPatch provides 8 fully differential analog input channels, 4 analog output channels, and 16 digital outputs (TTL). All I\/O channels are sampled continuously (200 kHz for analog inputs, 250 kHz for analog and digital outputs) and available through the user interface.\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ch2\u003eSUTTERPATCH SOFTWARE\u003c\/h2\u003e\n\u003cp\u003eThe dPatch amplifier system, in combination with SutterPatch software, has been engineered to automatically capture and store all amplifier settings, stimulus information and external experiment parameters, and associate them in time with the raw data traces. This includes all amplifier and acquisition settings, as well as timing and progress of the experiment. Fully integrated computer control of the amplifier stages means that the acquisition software is aware of the internal state of the amplifier and digitizer at all times and can track any changes that may occur. This is independent of whether a change is triggered automatically or initiated by the user.\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ch2\u003e\n\u003cspan style=\"color: red;\"\u003e●NEW FEATURE● \u003c\/span\u003eDYNAMIC CLAMP\u003c\/h2\u003e\n\u003cp\u003eThe patented digital architecture of the dPatch amplifier system provides an ideal platform for dynamic clamp. The dPatch is powered by a system-on-chip which provides parallel processing across a Field Programmable Gate Array (FPGA) and two high-speed ARM core processors. Several sophisticated dynamic clamp models are implemented within this architecture. In each model, the update of the applied current values occurs without communication between the dPatch and a computer. Depending upon the complexity of the model, update rates of up to 500 kHz can be achieved. \u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003ch2\u003eTRACKING OF OTHER EXTERNAL DATA\u003c\/h2\u003e\n\u003cp\u003eIn addition to status changes in connected hardware that are automatically tracked, the researcher can manually trigger tags to document events like stimulus application using instruments not connected to the amplifier. Information about environmental parameters and a more detailed specification of sample properties can be recorded and stored with the raw data. A total of over 650 metadata attributes are supported. Examples include: animal species, genotype, date\/time when a cell sample was prepared, recording solutions, pipette resistance, hardware properties, and detailed information about stimuli applied.\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eDATA VISUALIZATION AND ANALYSIS\u003c\/h2\u003e\n\u003cp\u003eSutterPatch software has been designed to simplify the navigation and analysis of complex datasets. The scope window supports multiple view modes in both two-dimensional and an innovative three-dimensional display. The 3D view is particularly useful during assay development. Built on top of the latest version of the proven Igor Pro platform, SutterPatch combines native Igor Pro functionality with a wealth of features that are tailored to electrophysiology applications. Both the newcomer and the experienced user of patch clamp programs will feel comfortable using SutterPatch software.\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eApplication modules provide focused functionality for particular applications.\u003cbr\u003e\u003cbr\u003e\u003cem\u003eCurrently available:\u003c\/em\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eEvent Detection Module: A deconvolution algorithm that excels at detecting miniature synaptic events even on a noisy background.\u003c\/li\u003e\n\u003cli\u003eAction Potential Analysis Module: Phase plane plot, timing and waveform statistics.\u003c\/li\u003e\n\u003cli\u003eCamera Module: An easy way to document the identity and condition of the recorded cell.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eA LABORATORY WORKHORSE\u003c\/h2\u003e\n\u003cp\u003eWhile the dPatch System is ready for cutting-edge research, its feature set makes it immediately valuable in any lab setting.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eThree headstage feedback ranges for optimal whole-cell and single-channel recording\u003c\/li\u003e\n\u003cli\u003eAutomated compensation of electrode and whole-cell capacitance\u003c\/li\u003e\n\u003cli\u003eSeries resistance compensation\u003c\/li\u003e\n\u003cli\u003eSimple cabling, quick and easy set-up\u003c\/li\u003e\n\u003cli\u003eHigh dynamic range of digitizer means no need for variable gain stages\u003c\/li\u003e\n\u003cli\u003eHigh speed of digitizer means no concern about sample rate\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003e\n\u003cbr\u003eCOMMON APPLICATIONS:\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli type=\"square\"\u003eSingle-channel recordings\u003c\/li\u003e\n\u003cli type=\"square\"\u003eAuditory research and other rapidly changing signals\u003c\/li\u003e\n\u003cli type=\"square\"\u003eTissue slice recordings\u003c\/li\u003e\n\u003cli type=\"square\"\u003eCultured cell experiments\u003c\/li\u003e\n\u003cli type=\"square\"\u003eCell line studies from adherent or dispersed cells\u003c\/li\u003e\n\u003cli type=\"square\"\u003eOptogenetics\u003c\/li\u003e\n\u003cli type=\"square\"\u003eNanopore and nanogap research\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eFEATURES\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eFree technical support\u003c\/li\u003e\n\u003cli\u003eFully integrated single- or dual-headstage patch clamp amplifier and data acquisition system ensures quick and easy setup\u003c\/li\u003e\n\u003cli\u003eOptimized for single-channel and whole-cell patch clamp recordings in tissue slices, adherent or dissociated cells\u003c\/li\u003e\n\u003cli\u003eFull computer control provides automated compensation of electrode and whole cell capacitance\u003c\/li\u003e\n\u003cli\u003eVoltage clamp, FastFollower™ current clamp and fully integrated dynamic clamp capability for complete characterization of cells' electrical activity\u003c\/li\u003e\n\u003cli\u003eLine frequency reduction in SutterPatch\u003c\/li\u003e\n\u003cli\u003eSoftware lock-in amplifier in SutterPatch for high-resolution capacitance measurements\u003c\/li\u003e\n\u003cli\u003eHigh bandwidth enables characterization of the fastest signals\u003c\/li\u003e\n\u003cli\u003eThree headstage feedback ranges for single-channel and whole-cell patch clamp recordings\u003c\/li\u003e\n\u003cli\u003eComprehensive digital compensation circuitry provides the utmost precision and signal fidelity\u003c\/li\u003e\n\u003cli\u003eBundled SutterPatch® software provides versatile data management, intuitive navigation and streamlined data analysis.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch2\u003eAccessories\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eGround Point\u003c\/strong\u003e\u003cbr\u003eThe Ground Point (#505673) provides reliable, low resistance connections for a star ground configuration, the proven method to avoid ground loops in any electrophysiology setup. Accepts 9 banana plugs + 8 bare wires up to 10 gauge or banana plugs. The baseplate mounts directly on imperial or metric air table tops with the included ¼-20 and M6 screws. Made of solid, machined brass with plated banana\/clamp connectors.\u003c\/p\u003e\n\u003cp align=\"center\"\u003e\u003ca rel=\"noopener\" href=\"https:\/\/www.sutter.com\/productLG\/gp-17_lg.jpg\" target=\"_blank\"\u003e\u003cimg align=\"center\" width=\"300\" alt=\"gp-17\" src=\"https:\/\/www.sutter.com\/productSM\/gp-17_sm.jpg\"\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003cp align=\"center\"\u003e\u003cbr\u003e\u003cstrong\u003edPatch Expansion Panel\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp align=\"center\"\u003e\u003ca rel=\"noopener\" href=\"https:\/\/www.sutter.com\/productLG\/dpa_expansion_3-4_lg.jpg\" target=\"_blank\"\u003e\u003cimg border=\"0\" align=\"center\" width=\"500\" alt=\"dPatch expansion\" src=\"https:\/\/www.sutter.com\/productSM\/dpa_expansion_3-4_sm.jpg\"\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003c!-- \/section:details --\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003c!-- section:resources --\u003e\n\u003ch2\u003eUser Manual\u003c\/h2\u003e\n\u003cp\u003e\u003ca rel=\"noopener\" href=\"https:\/\/www.sutter.com\/manuals\/dPatch_SutterPatch_OpMan.pdf\" title=\"\" target=\"_blank\"\u003edPatch \u0026amp; SutterPatch Operation Manual\u003c\/a\u003e\u003c\/p\u003e\n\u003ch2\u003ePRODUCT INFORMATION\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.sutter.com\/PDFs\/Comparison_aX.pdf\"\u003eComparison with Brand aX\u003c\/a\u003e\u003cbr\u003e\u003ca href=\"https:\/\/www.sutter.com\/Flyers\/DynamicClamp_flyer.pdf\"\u003eDynamic Clamp Flyer\u003c\/a\u003e\u003cbr\u003e\u003ca href=\"https:\/\/www.sutter.com\/Flyers\/DPA_flyer.pdf\"\u003edPatch Sales Flyer (English version)\u003c\/a\u003e\u003cbr\u003e\u003ca href=\"https:\/\/www.sutter.com\/Flyers\/SutterPatch_flyer.pdf\"\u003eSutterPatch® Sales Flyer\u003c\/a\u003e\u003cbr\u003e\u003ca href=\"https:\/\/www.sutter.com\/PDFs\/Comparison_Amplifier_Systems.pdf\"\u003eComparison of Sutter Amplifier Systems\u003c\/a\u003e\u003c\/p\u003e\n\u003ch2\u003eSCIENTIFIC PUBLICATIONS\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/www.sutter.com\/PDFs\/IPA_dPA_SutterPatch_Publications.pdf\"\u003eExperiments of interest involving Sutter Instrument amplifier systems and SutterPatch® software\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003ca rel=\"noopener\" href=\"https:\/\/www.sutter.com\/PDFs\/Patch_Clamp_Technology_TwentyFirst_Century.pdf\" target=\"_blank\"\u003eBook Chapter: Patch Clamp Technology in the Twenty-First Century\u003c\/a\u003e\u003cbr\u003eIn: \u003ca rel=\"noopener\" href=\"https:\/\/doi.org\/10.1007\/978-1-0716-0818-0_2\" target=\"_blank\"\u003eDallas M., Bell D. (eds) Patch Clamp Electrophysiology. Methods in Molecular Biology, vol 2188. Humana, New York, NY\u003c\/a\u003e\u003c\/p\u003e\n\u003ch2\u003eVIDEOS\u003c\/h2\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/youtu.be\/T2fKGV-eQl8\"\u003eWEBINAR: Dynamic Clamp and Cross-Experiment Analysis\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca rel=\"noopener\" href=\"https:\/\/youtu.be\/yQO33mOaO38\" target=\"_blank\"\u003eSutterPatch Informational Video\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/youtu.be\/fTAOWTVw8mc\"\u003eSutterPatch Walk-Through: #1 Introduction\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/youtu.be\/OaZ1mCtyb3I\"\u003eSutterPatch Walk-Through: #2 Amplifier Control\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/youtu.be\/IIzmJVZlL_E\"\u003eSutterPatch Walk-Through: #3 Routines\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/youtu.be\/HVMup1iDVCI\"\u003eSutterPatch Walk-Through: #4 Data Navigator and Metadata\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/youtu.be\/hpu_UJmJ3nM\"\u003eSutterPatch Walk-Through: #5 Application Modules\u003c\/a\u003e\u003c\/p\u003e\n\u003ch2\u003eFAQ\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eQ: How does dPatch® compare to other amplifiers on the market?\u003c\/strong\u003e\u003cbr\u003eA: The dPatch uses current state-of-the-art digital architecture. By converting the signal from analog to digital out near the headstage, we preserve the signal integrity as much as is possible. Almost every noise specification of the dPatch exceeds those of all other amplifiers on the market. In addition, the dPatch constitutes a complete patch clamp system, all data acquisition hard-and software are included, and no external hardware is required for dynamic clamp. \u003ca href=\"https:\/\/www.sutter.com\/PDFs\/Comparison_aX.pdf\"\u003e(see our comparison sheet)\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQ: Why doesn't the dPatch have active cooling?\u003c\/strong\u003e\u003cbr\u003eA: Active cooling causes numerous problems that actually create more \"noise\" in the long run. The heat generated by Peltier cells cause thermal drift in manipulators, making it almost impossible to stay patched while doing single-channel work. As a company that makes micromanipulators, we are highly sensitive to the performance of the system within a complete electrophysiology rig. Active cooling can help get a slightly better noise specification on paper, but in the real world the disadvantages far outweigh the slight gain in specsmanship (See the Comparison Sheet). In addition, the limited life expectancy of Peltier elements causes reliability concerns that we found unacceptable.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQ: Do I need to buy a digitizer or software with the dPatch?\u003c\/strong\u003e\u003cbr\u003eA: No, because the dPatch is inherently a digital design, no additional digitizer is necessary. SutterPatch® software and a license for IgorPro are included with every dPatch system. The dPatch includes everything you need to start running experiments.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQ: Can I retrofit a second headstage to my single-headstage dPatch system later?\u003c\/strong\u003e\u003cbr\u003eA: Yes, dPatch headstage\/preamplifier units are interchangeable and self-contained. All calibration and tuning information is stored directly in the headstage\/preamplifier unit and read during startup. That makes adding a second headstage easy.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQ: Do the headstages fit on my existing micromanipulator?\u003c\/strong\u003e\u003cbr\u003eA: All Sutter Instrument headstages come with a standard dovetail fitting. This fitting was jointly introduced by Sutter Instrument and Axon Instruments almost 30 years ago and has since been adopted by most manufacturers of patch clamp amplifiers and micromanipulators. That makes Sutter headstages a drop-in replacement on an existing rig, in most cases without even requiring any adjustment.\u003c\/p\u003e\n\u003c!-- \/section:resources --\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003c!-- section:specifications --\u003e\n\u003cp\u003eThe dPatch Integrated Digital Patch Clamp Amplifier is a computer-controlled single- or dual-headstage system optimized for both single-channel and whole-cell recording applications.\u003c\/p\u003e\n\u003cp align=\"center\"\u003e\u003ca rel=\"noopener\" href=\"https:\/\/www.sutter.com\/productLG\/dpa_back_lg.jpg\" target=\"_blank\"\u003e\u003cimg align=\"center\" width=\"645\" alt=\"dPatch back\" src=\"https:\/\/www.sutter.com\/productSM\/dpa_back_sm.jpg\"\u003e\u003c\/a\u003e\u003cbr\u003e\u003cem\u003eback panel of dPatch. (Click for larger view)\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch3\u003e\u003cem\u003eAmplifier\u003c\/em\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eHardware architecture enables all data conversion to be performed near the preparation, well away from known noise sources, such as power supplies and high-speed digital circuitry.\u003c\/li\u003e\n\u003cli\u003eVoltage clamp and true current clamp modes with smart switching between modes to avoid current artifacts\u003c\/li\u003e\n\u003cli\u003eThree choices of headstage feedback elements to optimize both single-channel and whole-cell recording\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ctable width=\"100%\" class=\"product-table\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth\u003e\u003ccenter\u003eFeedback\u003cbr\u003eElement\u003c\/center\u003e\u003c\/th\u003e\n\u003cth\u003e\u003ccenter\u003eRange\u003c\/center\u003e\u003c\/th\u003e\n\u003cth\u003e\u003ccenter\u003eAnalog\u003cbr\u003eBandwidth\u003c\/center\u003e\u003c\/th\u003e\n\u003cth\u003e\u003ccenter\u003eNoise\u003cbr\u003e10 kHz BW\u003c\/center\u003e\u003c\/th\u003e\n\u003cth\u003e\u003ccenter\u003ePipette\u003cbr\u003eCompensation\u003cbr\u003eRange\u003c\/center\u003e\u003c\/th\u003e\n\u003cth\u003e\u003ccenter\u003eSeries\u003cbr\u003eResistance\u003cbr\u003eRange\u003c\/center\u003e\u003c\/th\u003e\n\u003cth\u003e\u003ccenter\u003eCell\u003cbr\u003eCapacitance\u003cbr\u003eRange\u003c\/center\u003e\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003ccenter\u003eCapacitive\u003c\/center\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003ccenter\u003e±20 nA\u003c\/center\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003ccenter\u003e1 MHz\u003c\/center\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003ccenter\u003e\u0026lt; 0.22 pA\u003csub\u003erms\u003c\/sub\u003e\n\u003c\/center\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003ccenter\u003e20 pF\u003c\/center\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003ccenter\u003eN\/A*\u003c\/center\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003ccenter\u003eN\/A*\u003c\/center\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003ccenter\u003e500 MΩ\u003c\/center\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003ccenter\u003e±20 nA\u003c\/center\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003ccenter\u003e\u0026gt; 250 kHz\u003c\/center\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003ccenter\u003e\u0026lt; 0.7 pA\u003csub\u003erms\u003c\/sub\u003e\n\u003c\/center\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003ccenter\u003e20 pF\u003c\/center\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003ccenter\u003e100 MΩ\u003c\/center\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003ccenter\u003e100 pF\u003c\/center\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003e\u003ccenter\u003e50 MΩ\u003c\/center\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003ccenter\u003e±200 nA\u003c\/center\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003ccenter\u003e\u0026gt; 250 kHz\u003c\/center\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003ccenter\u003e\u0026lt; 2.3 pA\u003csub\u003erms\u003c\/sub\u003e\n\u003c\/center\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003ccenter\u003e20 pF\u003c\/center\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003ccenter\u003e10 MΩ\u003c\/center\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003ccenter\u003e1000 pF\u003c\/center\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e\u003cem\u003e\u003csup\u003e*\u003c\/sup\u003e Capacitive feedback range is optimized for single-channel voltage clamp recordings. Whole-cell compensation and current clamp mode are disabled with this range.\u003c\/em\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAutomatic compensation routines for pipette compensation and whole-cell compensation, and series resistance compensation\u003c\/li\u003e\n\u003cli\u003eSeries resistance prediction and correction independently programmable\u003c\/li\u003e\n\u003cli\u003e8-pole Bessel filter 0.1, 0.2, 0.5, 1, 2, 5, 10, 20, 50, 100, 250, 500, 1000 kHz\u003c\/li\u003e\n\u003cli\u003eSignal processing of filter output to increase resolution and reduce data file size\u003c\/li\u003e\n\u003cli\u003eResolution over 22 bits at 1 kHz filter setting\u003c\/li\u003e\n\u003cli\u003eHigh dynamic range of analog to digital converters alleviates need for variable output gain stages\u003c\/li\u003e\n\u003cli\u003eHolding potential ±1000 mV\u003c\/li\u003e\n\u003cli\u003eCurrent clamp bridge compensation and pipette capacitance compensation\u003c\/li\u003e\n\u003cli\u003eSlow holding potential tracking compensates for drift during current clamp recordings\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch3\u003e\u003cem\u003eData Acquisition\u003c\/em\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eEmbedded data acquisition system eliminates the need for an external data acquisition board\u003c\/li\u003e\n\u003cul\u003e\n\u003cli\u003e5 MHz sampling rate per headstage, 22-bit resolution\u003c\/li\u003e\n\u003cli\u003e8 Auxiliary analog inputs, 16-bit fully differential, ±10 V input, each continuously sampled at 200 kHz\u003c\/li\u003e\n\u003cli\u003e4 Analog outputs, 16-Bits, ±10 V output each continuously updated at 250 kHz\u003c\/li\u003e\n\u003cli\u003e16 Digital outputs (TTL) each running at 250 kHz\u003c\/li\u003e\n\u003cli\u003eIndependent Trigger IN \/ Trigger OUT for synchronization of external instrumentation\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cli\u003eSingle SuperSpeed USB 3.0 connection controls data acquisition and amplifier\u003c\/li\u003e\n\u003cli\u003eComplex command waveforms\u003c\/li\u003e\n\u003cli\u003eData acquisition can be initiated by an onboard microsecond clock or external (TTL) trigger\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003ch3\u003e\u003cem\u003eSutterPatch Software\u003c\/em\u003e\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eBuilt on the foundation of Igor Pro 8 (WaveMetrics, Inc.)\u003c\/li\u003e\n\u003cli\u003eParadigms and Routines provide complete experimental control\u003c\/li\u003e\n\u003cli\u003eWaveform Editor for easy creation of even the most complex stimulus patterns or user-defined templates\u003c\/li\u003e\n\u003cli\u003eAssociated Metadata stores all relevant information regarding your experiment\u003c\/li\u003e\n\u003cli\u003eComprehensive data analysis routines and publication-quality graphics\u003c\/li\u003e\n\u003cli\u003eRapid-response online line-frequency reduction\u003c\/li\u003e\n\u003cli\u003eRuns on Windows 10 or later (64-bit), or Macintosh OS X 10.11 (El Capitan) or newer versions\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp align=\"center\"\u003e\u003ca rel=\"noopener\" href=\"https:\/\/www.sutter.com\/productLG\/sutterpatch.jpg\" target=\"_blank\"\u003e\u003cimg align=\"center\" width=\"645\" alt=\"Sutterpatch\" src=\"https:\/\/www.sutter.com\/productLG\/sutterpatch.jpg\"\u003e\u003c\/a\u003e\u003cbr\u003e\u003cem\u003eScreenshot of SutterPatch Software\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTECHNICAL SPECIFICATIONS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDimensions\u003c\/strong\u003e\u003cbr\u003e\u003cem\u003edPatch:\u003c\/em\u003e 19 in x 11 in x 3.5 in | 48.2 cm x 28 cm x 9 cm\u003cbr\u003e\u003cbr\u003e\u003cem\u003edPatch Preamplifier:\u003c\/em\u003e 7.6 in x 3.5 in x 1.2 in | 19.5 cm x 9 cm x 3 cm\u003cbr\u003e\u003cbr\u003e\u003cem\u003edPatch Headstage:\u003c\/em\u003e 3.7 in x 1.1 in x 0.66 in | 9.5 cm x 2.9 cm x 1.7 cm\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eWeight\u003c\/strong\u003e\u003cbr\u003e\u003cem\u003edPatch:\u003c\/em\u003e 15 lbs | 6.8 kg\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eElectrical\u003c\/strong\u003e\u003cbr\u003e110\/240 Volts\u003cbr\u003e50\/60 Hertz power line\u003cbr\u003e\u003cbr\u003e*Patent No. US 10,393,727 B2\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eRoHS Compliant\u003c\/strong\u003e\u003cbr\u003e\u003cbr\u003e\u003ca rel=\"noopener\" href=\"https:\/\/www.sutter.com\/PDFs\/CE\/CE_EU_DoC_DPATCH.pdf\" target=\"_blank\"\u003eDPATCH CE Certificate\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003cimg height=\"53\" width=\"75\" alt=\"CE logo\" src=\"https:\/\/www.sutter.com\/images\/structure\/ce-marking-logo.png\"\u003e   \u003cimg height=\"50\" width=\"50\" alt=\"UKCA\" src=\"https:\/\/www.sutter.com\/images\/structure\/UKCA_74.png\"\u003e   \u003cimg height=\"57\" width=\"65\" alt=\"Chiana CE\" src=\"https:\/\/www.sutter.com\/images\/structure\/China_CE_97.png\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSYSTEM REQUIREMENTS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003eMinimum Configuration:\u003c\/em\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eWindows 10 (64-bit), or MacOS: 10.11, El Capitan or later\u003csup\u003e1\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eProcessor: Dual-core i5\u003csup\u003e2\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eMemory: 8 GB\u003c\/li\u003e\n\u003cli\u003eSolid-state drive (SSD): 500 GB or greater\u003c\/li\u003e\n\u003cli\u003eDisplay Resolution: 1024 x 768 (XGA)\u003c\/li\u003e\n\u003cli\u003e1 available USB 3.0 SuperSpeed port (on the main board, not a PCIx card or similar)\u003csup\u003e3\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cbr\u003e\u003cem\u003eRecommended Configuration for Bandwidths of \u0026gt;50 kHz:\u003c\/em\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eWindows 10 (64-bit), or MacOS: 10.11, El Capitan or later\u003csup\u003e1\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eProcessor: Dual-core i5\u003csup\u003e2\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eMemory: 16 GB\u003c\/li\u003e\n\u003cli\u003eSolid-state drive (SSD): 500 GB or greater\u003c\/li\u003e\n\u003cli\u003eDisplay resolution 1920 x 1080 (Full HD)\u003c\/li\u003e\n\u003cli\u003e1 available USB 3.0 SuperSpeed port (on the main board, not a PCIx card or similar)\u003csup\u003e3\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eSUTTERPATCH® Data Acquisition Management System and Analysis Software: Included with all Sutter Instrument Amplifier Systems\u003c\/p\u003e\n\u003cp\u003e\u003cem\u003e\u003csup\u003e1\u003c\/sup\u003e Operating systems installed within virtualization software platforms such as VMware and Parallels are not supported.\u003cbr\u003e\u003cbr\u003e\u003csup\u003e2\u003c\/sup\u003e At this point, WaveMetrics does not fully support Igor Pro on Mac computers based on the Apple Silicon M1 architecture. See \u003ca rel=\"noopener\" href=\"https:\/\/www.wavemetrics.com\/news\/igor-and-apple-arm-processors\" target=\"_blank\"\u003ehttps:\/\/www.wavemetrics.com\/news\/igor-and-apple-arm-processors\u003c\/a\u003e for technical details. Preliminary experiments indicate that SutterPatch Software runs on these computers, both under Igor Pro 8 and 9, and with each of the Sutter Amplifier Systems connected. However, as with each new technology, we cannot fully exclude incompatibilities.\u003cbr\u003e\u003cbr\u003e\u003csup\u003e3\u003c\/sup\u003e USB 3.0 ports are compatible with USB 2.0 High Speed specifications.\u003cbr\u003eSlower USB 2.0 ‘full-speed’ ports, which are sometimes found on older Windows PCs or USB add-in cards, are not supported.\u003cbr\u003e\u003cbr\u003eTo check for High Speed USB 2.0 or USB 3.0 on a PC computer running Windows, look in the Control Panel \u0026gt; Device Manager \u0026gt; Universal Serial Bus controllers section for “Enhanced” host controllers. As this does not provide any mapping information to the computer’s physical ports, and there can be a mix of USB port versions, you should check individual USB ports for USB 2.0\/3.0 High Speed operational performance. As a visual indicator, USB 3.0 ports are often color coded blue.\u003cbr\u003e\u003cbr\u003eUSB hubs are not supported. USB add-in cards, even if they formally meet High Speed or Super Speed specifications, are not recommended. They are often architecturally configured as USB hubs and may lead to intermittent transfer errors that are hard to troubleshoot.\u003cbr\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cimg height=\"53\" width=\"75\" alt=\"CE logo\" src=\"https:\/\/www.sutter.com\/images\/structure\/ce-marking-logo.png\"\u003e\u003cbr\u003e\u003cimg height=\"59\" width=\"72\" alt=\"RoHS\" src=\"https:\/\/www.sutter.com\/images\/structure\/rohs.jpg\"\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003c!-- \/section:specifications --\u003e","brand":"World Precision Instruments","offers":[{"title":"dPatch system with one headstage and preamp","offer_id":42267582464090,"sku":"SU-DPATCH","price":29630.01,"currency_code":"USD","in_stock":true},{"title":"dPatch system with two headstages and preamp","offer_id":42267582496858,"sku":"SU-DPATCH-2","price":35829.58,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/7993\/1994\/files\/double_dpa_lg_c7fa529a-e687-4700-bbc0-31dea413bb84.jpg?v=1766414927"},{"product_id":"var-su-ipa-ipa-system","title":"IPA system","description":"\u003c!-- section:details --\u003e\n\u003ch2\u003eOptions\u003c\/h2\u003e\r\n\u003ctable class=\"product-table\" style=\"height: 54px; width: 100%;\" width=\"100%\"\u003e\r\n\u003ctbody\u003e\r\n\u003ctr style=\"height: 18px;\"\u003e\r\n\u003ctd style=\"text-align: center; height: 18px; width: 15.2358%;\"\u003e\u003cstrong\u003eOrder code\u003c\/strong\u003e\u003c\/td\u003e\r\n\u003ctd style=\"text-align: center; height: 18px; width: 36.5175%;\"\u003e\u003cstrong\u003eDescription\u003c\/strong\u003e\u003c\/td\u003e\r\n\u003ctd style=\"text-align: center; width: 48.2467%;\"\u003e\u003cstrong\u003eDetails\u003c\/strong\u003e\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr style=\"height: 18px;\"\u003e\r\n\u003ctd style=\"height: 18px; width: 15.2358%;\"\u003eSU-IPA\u003c\/td\u003e\r\n\u003ctd style=\"height: 18px; width: 36.5175%;\"\u003eIPA system with headstage\u003c\/td\u003e\r\n\u003ctd style=\"width: 48.2467%;\"\u003eIncludes: IPA system with headstage, 505671 pipette holder, model cell, “octopus” breakout cable, rack mounting hardware; SutterPatch® software suite with Igor Pro license\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr style=\"height: 18px;\"\u003e\r\n\u003ctd style=\"height: 18px; width: 15.2358%;\"\u003eSU-IPA2\u003c\/td\u003e\r\n\u003ctd style=\"height: 18px; width: 36.5175%;\"\u003eDouble IPA system with two headstages\u003c\/td\u003e\r\n\u003ctd style=\"width: 48.2467%;\"\u003eIncludes: Double IPA system with two headstages, two 505671 pipette holders, model cell, “octopus” breakout cable, rack mounting hardware; SutterPatch® software suite with Igor Pro license.\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003c\/tbody\u003e\r\n\u003c\/table\u003e\r\n\u003ch2\u003eExternal Inputs \u0026amp; Outputs\u003c\/h2\u003e\r\n\u003cp\u003eExternal signals, such as environmental parameters or stimulus information, can be recorded using 4 auxiliary analog input channels. The IPA systems also support the control of peripheral hardware, such as wavelength or solution switchers, with 2 analog and 8 digital (TTL) output channels. As an alternative to the standard breakout cable, an optional Patch Panel provides a tidy way of connecting auxiliary signals on the front of your rack.\u003c\/p\u003e\r\n\u003ch2\u003eSutterPatch Software\u003c\/h2\u003e\r\n\u003cp\u003eThe IPA system, in combination with SutterPatch software, has been engineered to automatically capture and store all amplifier settings, stimulus information and external experiment parameters and associate them in time with the raw data traces. This includes all amplifier and acquisition settings, as well as timing and progress of the experiment. Fully integrated computer control of the amplifier stages means that the acquisition software is aware of the internal state of the amplifier and digitizer at all times and can track any changes that may occur. This is independent of whether a change is triggered automatically or initiated by the user.\u003c\/p\u003e\r\n\u003ch2\u003eTracking of Other External Data\u003c\/h2\u003e\r\n\u003cp\u003eIn addition to status changes in connected hardware that are automatically tracked, the experimenter can manually trigger tags to document events like stimulus application in instruments not connected to the IPA system.\u003cbr\u003e\u003cbr\u003eInformation about environmental parameters and a more detailed specification of sample properties can be recorded and stored with the raw data. A total of over 600 metadata attributes are supported. Examples include: animal species, strain, genotype, date\/time when a cell sample was prepared, recording solutions, pipette resistance, hardware properties, and detailed information about stimuli applied.\u003c\/p\u003e\r\n\u003ch2\u003eData Visualization and Analysis\u003c\/h2\u003e\r\n\u003cp\u003eSutterPatch software has been designed to simplify the navigation and analysis of complex datasets. The scope window supports multiple view modes in both two-dimensional and an innovative three-dimensional display. The 3D view is particularly useful during assay development. Built on top of the latest version of the proven Igor Pro platform, the SutterPatch program combines native Igor Pro functionality with a wealth of features that are tailored to electrophysiology applications. Both the newcomer and experienced user of patch clamp programs will feel comfortable using SutterPatch software.\u003c\/p\u003e\r\n\u003cp\u003eApplication modules provide focused functionality for particular applications.\u003c\/p\u003e\r\n\u003cul\u003eCurrently available:\r\n\u003cli\u003e\n\u003cem\u003eEvent Detection Module:\u003c\/em\u003e A deconvolution algorithm that excels at detecting miniature synaptic events even on a noisy background\u003c\/li\u003e\r\n\u003cli\u003e\n\u003cem\u003eAction Potential Analysis Module:\u003c\/em\u003e Phase plane plot, timing and waveform statistics\u003c\/li\u003e\r\n\u003cli\u003e\n\u003cem\u003eCamera Module:\u003c\/em\u003e An easy way to document the identity and condition of the recorded cell\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003cp\u003eThe IPA and Double IPA Integrated Patch Clamp Amplifiers are computer-controlled single- or dual-headstage amplifiers optimized for whole-cell recording applications.\u003c\/p\u003e\r\n\u003ch2 style=\"text-align: left;\" align=\"center\"\u003eCOMMON APPLICATIONS\u003c\/h2\u003e\r\n\u003cdiv\u003e\r\n\u003cul\u003e\r\n\u003cli type=\"square\"\u003eTissue slice recordings\u003c\/li\u003e\r\n\u003cli type=\"square\"\u003eCultured-cell experiments\u003c\/li\u003e\r\n\u003cli type=\"square\"\u003eCell line studies from adherent or dispersed cells\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003c\/div\u003e\r\n\u003cdiv\u003e\r\n\u003cul\u003e\r\n\u003cli type=\"square\"\u003e\n\u003cem\u003eIn-vivo\u003c\/em\u003e patch clamp\u003c\/li\u003e\r\n\u003cli type=\"square\"\u003eNetwork studies\u003c\/li\u003e\r\n\u003cli type=\"square\"\u003eOptogenetics\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003c\/div\u003e\r\n\u003cdiv\u003e \u003c\/div\u003e\r\n\u003ch2\u003eFEATURES\u003c\/h2\u003e\r\n\u003cul\u003e\r\n\u003cli\u003e\n\u003cstrong\u003eNEW:\u003c\/strong\u003e Combination of any two IPA or Double IPA devices enables up to four headstage channels for as many as 16 signals\u003c\/li\u003e\r\n\u003cli\u003eFully integrated patch clamp amplifier and data acquisition system ensures quick and easy setup\u003c\/li\u003e\r\n\u003cli\u003eOptimized for whole-cell patch clamp recordings in tissue slices, adherent or dissociated cells\u003c\/li\u003e\r\n\u003cli\u003eFull computer control provides automated compensation of electrode and whole cell capacitance\u003c\/li\u003e\r\n\u003cli\u003eVoltage and current clamp capability for complete characterization of cells' electrical activity\u003c\/li\u003e\r\n\u003cli\u003eBundled SutterPatch software excels in comprehensive data management, intuitive navigation and streamlined data analysis\u003c\/li\u003e\r\n\u003cli\u003eLine frequency reduction in SutterPatch\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003cp\u003e \u003c\/p\u003e\r\n\u003ch2 style=\"text-align: left;\" align=\"center\"\u003eACCESSORIES\u003c\/h2\u003e\r\n\u003cp\u003e\u003cstrong\u003eOptional IPA Patch Panel\u003c\/strong\u003e\u003cbr\u003eThe IPA and Double IPA Amplifiers come standard with an \"octopus\" breakout cable for auxiliary inputs and outputs, and digital outputs. The optional IPA Patch Panel, machined from ½\" thick billet aluminum stock like the IPA faceplate, brings the auxiliary I\/O connections to the front of the rack in a tidy 2U rack mount panel with BNC connectors. The IPA Patch Panel includes a 2.5 ft (76 cm) connector cable and replaces the standard cable that ships with the IPA system.\u003cbr\u003e\u003ca href=\"https:\/\/www.sutter.com\/productLG\/ipa_patch_lg.jpg\" target=\"_blank\" rel=\"noopener\"\u003e\u003cimg src=\"https:\/\/www.sutter.com\/productSM\/ipa_patch_sm.jpg\" alt=\"IPA patch\" width=\"645\" align=\"center\"\u003e\u003c\/a\u003e\u003cbr\u003e\u003cstrong\u003eGround Point\u003c\/strong\u003e\u003cbr\u003eThe Ground Point (505673) provides reliable, low resistance connections for star ground connections, the proven method to avoid ground loops in any electrophysiology setup. Accepts 9 banana plugs + 8 bare wires up to 10 gauge or banana plugs. The baseplate mounts directly on standard or metric air table tops with the included ¼-20 and M6 screws. Made of solid, machined brass with plated banana\/clamp connectors.\u003c\/p\u003e\r\n\u003cp align=\"center\"\u003e\u003ca href=\"https:\/\/www.sutter.com\/productLG\/gp-17_lg.jpg\" target=\"_blank\" rel=\"noopener\"\u003e\u003cimg src=\"https:\/\/www.sutter.com\/productSM\/gp-17_sm.jpg\" alt=\"GP 17\" width=\"300\" align=\"center\"\u003e\u003c\/a\u003e\u003c\/p\u003e\n\u003c!-- \/section:details --\u003e\n\n\u003c!-- section:resources --\u003e\n\u003ch2\u003eUSER MANUALS\u003c\/h2\u003e\r\n\u003cp\u003e\u003ca href=\"https:\/\/www.sutter.com\/manuals\/IPA_SutterPatch_QSGuide.pdf\" target=\"new\"\u003eIPA \u0026amp; SutterPatch Quick Start Guide\u003c\/a\u003e\u003cbr\u003e\u003ca href=\"https:\/\/www.sutter.com\/manuals\/IPA_SutterPatch_OpMan.pdf\" target=\"new\"\u003eIPA \u0026amp; SutterPatch Operation Manual\u003c\/a\u003e\u003c\/p\u003e\r\n\u003ch2\u003ePRODUCT INFORMATION\u003c\/h2\u003e\r\n\u003cp\u003e\u003cstrong\u003eIPA \/ DOUBLE IPA Sales Flyer:\u003c\/strong\u003e \u003ca href=\"https:\/\/www.sutter.com\/Flyers\/IPA_flyer.pdf\" target=\"new\"\u003eEnglish\u003c\/a\u003e \/ \u003ca href=\"https:\/\/www.sutter.com\/Flyers\/IPA_flyer_china.pdf\" target=\"new\"\u003eChinese\u003c\/a\u003e\u003cbr\u003e\u003ca href=\"https:\/\/www.sutter.com\/Flyers\/SutterPatch_flyer.pdf\" target=\"new\"\u003eSutterPatch Sales Flyer\u003c\/a\u003e\u003cbr\u003e\u003ca href=\"https:\/\/www.sutter.com\/PDFs\/Comparison_Amplifier_Systems.pdf\" target=\"new\"\u003eComparison of Sutter Amplifier Systems\u003c\/a\u003e\u003cbr\u003e\u003ca href=\"https:\/\/youtu.be\/yQO33mOaO38\" target=\"_blank\" rel=\"noopener\"\u003eSutterPatch Informational Video\u003c\/a\u003e\u003c\/p\u003e\r\n\u003ch2\u003eSCIENTIFIC PUBLICATIONS\u003c\/h2\u003e\r\n\u003cp\u003e\u003ca href=\"https:\/\/www.sutter.com\/PDFs\/IPA_dPA_SutterPatch_Publications.pdf\" target=\"new\"\u003eExperiments of interest involving Sutter Instrument amplifier systems and SutterPatch® software\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/www.sutter.com\/PDFs\/Patch_Clamp_Technology_TwentyFirst_Century.pdf\" target=\"_blank\" rel=\"noopener\"\u003eBook Chapter: Patch Clamp Technology in the Twenty-First Century\u003c\/a\u003e\u003cbr\u003eIn: \u003ca href=\"https:\/\/doi.org\/10.1007\/978-1-0716-0818-0_2\" target=\"_blank\" rel=\"noopener\"\u003eDallas M., Bell D. (eds) Patch Clamp Electrophysiology. Methods in Molecular Biology, vol 2188. Humana, New York, NY\u003c\/a\u003e\u003c\/p\u003e\r\n\u003ch2\u003eVIDEOS\u003c\/h2\u003e\r\n\u003cp\u003e\u003ca href=\"https:\/\/youtu.be\/yQO33mOaO38\" target=\"_blank\" rel=\"noopener\"\u003eSutterPatch Informational Video\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/youtu.be\/fTAOWTVw8mc\" target=\"new\"\u003eSutterPatch Walk-Through: #1 Introduction\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/youtu.be\/OaZ1mCtyb3I\" target=\"new\"\u003eSutterPatch Walk-Through: #2 Amplifier Control\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/youtu.be\/IIzmJVZlL_E\" target=\"new\"\u003eSutterPatch Walk-Through: #3 Routines\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/youtu.be\/HVMup1iDVCI\" target=\"new\"\u003eSutterPatch Walk-Through: #4 Data Navigator and Metadata\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/youtu.be\/hpu_UJmJ3nM\" target=\"new\"\u003eSutterPatch Walk-Through: #5 Application Modules\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/youtu.be\/T2fKGV-eQl8\" target=\"new\"\u003eWEBINAR: Dynamic Clamp and Cross-Experiment Analysis\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/v.youku.com\/v_show\/id_XNDY0Mzk5OTUyNA\" target=\"new\"\u003eWEBINAR: Dynamic Clamp and Cross-Experiment Analysis (Youku)\u003c\/a\u003e\u003c\/p\u003e\n\u003c!-- \/section:resources --\u003e\n\n\u003c!-- section:specifications --\u003e\n\u003ch2\u003eAmplifier\u003c\/h2\u003e\r\n\u003cul\u003e\r\n\u003cli\u003eVoltage clamp and true current clamp modes with smart switching between modes to avoid current artifacts\u003c\/li\u003e\r\n\u003cli\u003eOpen-Circuit (RMS) noise of 1.4 pA in a 0.1-10 kHz bandwidth\u003c\/li\u003e\r\n\u003cli\u003e500 MΩ headstage feedback resistor provides a max. range of ±20 nA\u003c\/li\u003e\r\n\u003cli\u003eFast pipette capacitance compensation and whole-cell compensation\u003c\/li\u003e\r\n\u003cul\u003e\r\n\u003cli\u003ePipette capacitance compensation up to 25 pF\u003c\/li\u003e\r\n\u003cli\u003eWhole-cell compensation: C\u003csub\u003em\u003c\/sub\u003e from 1-100 pF ; R\u003csub\u003es\u003c\/sub\u003e from 1-100 MΩ\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003cli\u003eOnboard automatic compensation routines\u003c\/li\u003e\r\n\u003cli\u003eSeries resistance prediction and correction (0-100 MΩ)\u003c\/li\u003e\r\n\u003cli\u003eFour-pole Bessel low-pass filter (cutoff = 0.5 – 20 kHz)\u003c\/li\u003e\r\n\u003cli\u003eOutput gain: 0.5-25 mV\/pA (voltage clamp); 10-500 mV\/mV (current clamp)\u003c\/li\u003e\r\n\u003cli\u003eHolding potential ±1000 mV\u003c\/li\u003e\r\n\u003cli\u003eCurrent clamp bridge compensation and capacitance neutralization\u003c\/li\u003e\r\n\u003cli\u003eSlow holding potential tracking compensates for drift during current clamp recordings\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003ch2\u003eData Acquisition\u003c\/h2\u003e\r\n\u003cul\u003e\r\n\u003cli\u003eEmbedded data acquisition system eliminates the need for an external data acquisition board and facilitates setup\u003c\/li\u003e\r\n\u003cli\u003eSingle high-speed USB connection controls data acquisition and amplifier\u003c\/li\u003e\r\n\u003cli\u003eUp to 6 or 8 input channels (0.1 - 50 kHz sampling rate per channel)\u003c\/li\u003e\r\n\u003cli\u003eUp to 400 kHz aggregate sampling rate\u003c\/li\u003e\r\n\u003cli\u003eMulti-amplifier mode: A combination of any two IPA or Double IPA Amplifiers can be connected, providing up to 16 input channels\u003c\/li\u003e\r\n\u003cli\u003eComplex command waveforms\u003c\/li\u003e\r\n\u003cli\u003eAuxiliary input \/ output for control of other instrumentation\u003c\/li\u003e\r\n\u003cul\u003e\r\n\u003cli\u003e4 analog input channels (±10 V)\u003c\/li\u003e\r\n\u003cli\u003e2 analog output channels (±10 V)\u003c\/li\u003e\r\n\u003cli\u003e8 digital output channels (TTL)\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003cli\u003eData acquisition can be initiated by an onboard microsecond clock or external (TTL) trigger\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003ch2\u003eSutterPatch® Software\u003c\/h2\u003e\r\n\u003cul\u003e\r\n\u003cli\u003eBuilt on the foundation of Igor Pro (WaveMetrics, Inc.)\u003c\/li\u003e\r\n\u003cli\u003eParadigms and Routines provide complete experimental control\u003c\/li\u003e\r\n\u003cli\u003eWaveform Editor for easy creation of even the most complex stimulus patterns or user-defined templates\u003c\/li\u003e\r\n\u003cli\u003eAssociated metadata stores all relevant information regarding your experiment\u003c\/li\u003e\r\n\u003cli\u003eComprehensive data analysis routines and publication quality graphics\u003c\/li\u003e\r\n\u003cli\u003eRuns on Windows 10 or later (64-bit) or Mac OS X 10.11 (El Capitan) or later\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003cp\u003e\u003ca href=\"https:\/\/www.sutter.com\/productLG\/sutterpatch.jpg\" target=\"_blank\" rel=\"noopener\"\u003e\u003cimg src=\"https:\/\/www.sutter.com\/productLG\/sutterpatch.jpg\" alt=\"Sutter patch\" width=\"645\" align=\"center\"\u003e\u003c\/a\u003e \u003c\/p\u003e\r\n\u003cp\u003e\u003cem\u003eScreenshot of SutterPatch Software\u003c\/em\u003e\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\r\n\u003ch2\u003eTECHNICAL SPECIFICATIONS\u003c\/h2\u003e\r\n\u003cp\u003e\u003cstrong\u003eDimensions\u003c\/strong\u003e\u003cbr\u003e\u003cem\u003eIPA®:\u003c\/em\u003e 18.8 in x 11.8 in x 1.8 in | 48 cm x 30 cm x 4.5 cm\u003cbr\u003e\u003cem\u003eDOUBLE IPA®:\u003c\/em\u003e 18.8 in x 11.8 in x 3.5 in | 48 cm x 30 cm x 9 cm\u003cbr\u003e\u003cem\u003eIPA Headstage:\u003c\/em\u003e 4.0 in x 1.4 in x 0.75 in | 10 cm x 3.5 cm x 1.9 cm\u003cbr\u003e\u003cem\u003ePatch Panel:\u003c\/em\u003e 18.8 in x 2.0 in x 3.5 in | 48 cm x 5 cm x 9 cm\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eWeight\u003c\/strong\u003e\u003cbr\u003e\u003cem\u003eIPA:\u003c\/em\u003e 9 lbs | 4 kg\u003cbr\u003e\u003cem\u003eDOUBLE IPA:\u003c\/em\u003e 8.1 lbs | 3.7 kg\u003cbr\u003e\u003cem\u003ePatch Panel:\u003c\/em\u003e 3.5 lbs | 1.6 kg\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eElectrical\u003c\/strong\u003e\u003cbr\u003e110\/240 Volts\u003cbr\u003e50\/60 Hertz power line\u003c\/p\u003e\r\n\u003cp\u003e\u003cstrong\u003eRoHS Compliant\u003c\/strong\u003e\u003cbr\u003e\u003cbr\u003e\u003ca href=\"https:\/\/www.sutter.com\/PDFs\/CE\/CE_EU_DoC_IPA_DOUBLE_IPA.pdf\" target=\"_blank\" rel=\"noopener\"\u003eIPA \u0026amp; DOUBLE IPA CE Certificate\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003cimg src=\"https:\/\/www.sutter.com\/images\/structure\/ce-marking-logo.png\" alt=\"CE\" width=\"75\" height=\"53\"\u003e   \u003cimg src=\"https:\/\/www.sutter.com\/images\/structure\/UKCA_74.png\" alt=\"UK CE\" width=\"50\" height=\"50\"\u003e   \u003cimg src=\"https:\/\/www.sutter.com\/images\/structure\/China_CE_97.png\" alt=\"China CE\" width=\"65\" height=\"57\"\u003e\u003c\/p\u003e\r\n\u003cp\u003e\u003cstrong\u003eSYSTEM REQUIREMENTS\u003c\/strong\u003e\u003c\/p\u003e\r\n\u003cp\u003e\u003cem\u003eMinimum Configuration:\u003c\/em\u003e\u003c\/p\u003e\r\n\u003cul\u003e\r\n\u003cli\u003eWindows 10 (64-bit), or MacOS: 10.11, El Capitan or later\u003csup\u003e1\u003c\/sup\u003e\n\u003c\/li\u003e\r\n\u003cli\u003eProcessor: Dual-core i5\u003csup\u003e2\u003c\/sup\u003e\n\u003c\/li\u003e\r\n\u003cli\u003eMemory: 3 GB\u003c\/li\u003e\r\n\u003cli\u003eHard Disk: 500 GB or greater\u003c\/li\u003e\r\n\u003cli\u003eDisplay Resolution: 1024 x 768 (XGA)\u003c\/li\u003e\r\n\u003cli\u003e1 available USB 2.0 High Speed port\u003csup\u003e3\u003c\/sup\u003e\n\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003cp\u003e\u003cbr\u003e\u003cem\u003eRecommended Configuration for Bandwidths of \u0026gt;50 kHz:\u003c\/em\u003e\u003c\/p\u003e\r\n\u003cul\u003e\r\n\u003cli\u003eWindows 10 (64-bit), or MacOS: 10.11, El Capitan or later\u003csup\u003e1\u003c\/sup\u003e\n\u003c\/li\u003e\r\n\u003cli\u003eProcessor: Dual-core i5\u003csup\u003e2\u003c\/sup\u003e\n\u003c\/li\u003e\r\n\u003cli\u003eMemory: 8 GB\u003c\/li\u003e\r\n\u003cli\u003eSolid-state drive (SSD): 500 GB or greater\u003c\/li\u003e\r\n\u003cli\u003eDisplay resolution 1920 x 1080 (Full HD)\u003c\/li\u003e\r\n\u003cli\u003e1 available USB 2.0 High Speed port\u003csup\u003e3\u003c\/sup\u003e\n\u003c\/li\u003e\r\n\u003c\/ul\u003e\r\n\u003cp\u003e \u003c\/p\u003e\r\n\u003cp\u003eSUTTERPATCH® Data Acquisition Management System and Analysis Software: Included with all Sutter Instrument Amplifier Systems\u003c\/p\u003e\r\n\u003cp\u003e\u003cem\u003e\u003csup\u003e1\u003c\/sup\u003e Operating systems installed within virtualization software platforms such as VMware and Parallels are not supported.\u003cbr\u003e\u003cbr\u003e\u003csup\u003e2\u003c\/sup\u003e At this point, WaveMetrics does not fully support Igor Pro on Mac computers based on the Apple Silicon M1 architecture. See \u003ca href=\"https:\/\/www.wavemetrics.com\/news\/igor-and-apple-arm-processors\" target=\"_blank\" rel=\"noopener\"\u003ehttps:\/\/www.wavemetrics.com\/news\/igor-and-apple-arm-processors\u003c\/a\u003e for technical details. Preliminary experiments indicate that SutterPatch Software runs on these computers, both under Igor Pro 8 and 9, and with each of the Sutter Amplifier Systems connected. However, as with each new technology, we cannot fully exclude incompatibilities.\u003cbr\u003e\u003cbr\u003e\u003csup\u003e3\u003c\/sup\u003e USB 3.0 ports are compatible with USB 2.0 High Speed specifications.\u003cbr\u003eSlower USB 2.0 ‘full-speed’ ports, which are sometimes found on older Windows PCs or USB add-in cards, are not supported.\u003cbr\u003e\u003cbr\u003eTo check for High Speed USB 2.0 or USB 3.0 on a PC computer running Windows, look in the Control Panel \u0026gt; Device Manager \u0026gt; Universal Serial Bus controllers section for “Enhanced” host controllers. As this does not provide any mapping information to the computer’s physical ports, and there can be a mix of USB port versions, you should check individual USB ports for USB 2.0\/3.0 High Speed operational performance. As a visual indicator, USB 3.0 ports are often color coded blue.\u003cbr\u003e\u003cbr\u003eUSB hubs are not supported. USB add-in cards, even if they formally meet High Speed or Super Speed specifications, are not recommended. They are often architecturally configured as USB hubs and may lead to intermittent transfer errors that are hard to troubleshoot.\u003cbr\u003e\u003c\/em\u003e\u003c\/p\u003e\n\u003c!-- \/section:specifications --\u003e","brand":"World Precision Instruments","offers":[{"title":"Double IPA system with two headstages","offer_id":42267583152218,"sku":"SU-IPA2","price":22197.5,"currency_code":"USD","in_stock":true},{"title":"IPA system with headstage","offer_id":42267583184986,"sku":"SU-IPA","price":17231.9,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/7993\/1994\/files\/ipa_dipa_lg_1_5bd1743b-856a-41c7-8862-4f1e9e17204b.jpg?v=1766414954"},{"product_id":"iso-80-isolated-differential-amplifier-with-active-probe","title":"Isolated Differential Amplifier with active probe","description":"\u003c!-- section:details --\u003e\n\u003cp\u003e\u003ca href=\"\/blog\/post\/wpi-s-low-noise-amplifiers-outperform-cheap-imitations\/\"\u003eSee what you need to know before you buy an amplifier.\u003c\/a\u003e\u003c\/p\u003e\n\u003ch2\u003eExcellent recording performance for extracellular nerve AP\u003c\/h2\u003e\n\u003ch2\u003eFeatures\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eBattery powered, rechargeable\u003c\/li\u003e\n\u003cli\u003eHigh pass and low pass filtering\u003c\/li\u003e\n\u003cli\u003eActive remote headstage\u003c\/li\u003e\n\u003cli\u003eAC only amplification\u003c\/li\u003e\n\u003cli\u003eElectrode impedance test function\u003c\/li\u003e\n\u003cli\u003eElectrode current generation with polarity select\u003c\/li\u003e\n\u003cli\u003eVariable output positioning\u003c\/li\u003e\n\u003cli\u003eThe ISO-80P replacement probe does not need the ISO-80 to be sent in for calibration\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eThe startup kit includes 2-CBL102, 2-5469, 2-13388, 3294, 2033, 2034, 2-2035, 2-M3301EH, 5470, EP1.\u003c\/p\u003e\n\u003ch2\u003eBenefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eUltra quiet DC power supply\u003c\/li\u003e\n\u003cli\u003eIntrinsic low susceptibility to ground loops\u003c\/li\u003e\n\u003cli\u003eHigh signal to noise ratio due to remote head stage\u003c\/li\u003e\n\u003cli\u003eSmall footprint\u003c\/li\u003e\n\u003cli\u003eStimulation\/histological marking current\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eApplications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAmplifying bio-potentials using metal microelectrodes\u003c\/li\u003e\n\u003cli\u003eBrain slice field potentials\u003c\/li\u003e\n\u003cli\u003eEAG (Electroantennogram)\u003c\/li\u003e\n\u003cli\u003eERG (Electroretinogram)\u003c\/li\u003e\n\u003cli\u003eMonitor extracellular nerve action potentials\u003c\/li\u003e\n\u003cli\u003eUse for cell marking, stimulation or electrode cleaning\u003c\/li\u003e\n\u003cli\u003e\n\u003cem\u003eIn vivo\u003c\/em\u003e cortical recording\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eStartup Kit\u003c\/h2\u003e\n\u003cp\u003eIncluded with the ISO-80 is a Startup Kit containing the following accessories needed for basic metal electrode electrophysiology research:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eCBL102 Cable, BNC-to-3.5 mm plug 6 ft. (2m) (two)\u003c\/li\u003e\n\u003cli\u003e5469 Adapter, mini-banana to 0.031 socket (two)\u003c\/li\u003e\n\u003cli\u003e13388 Adapter, mini-banana to 2mm socket (two)\u003c\/li\u003e\n\u003cli\u003e3294 Cable, ground clip to wire, 3 ft.\u003c\/li\u003e\n\u003cli\u003e2033 Mini-banana plug, black\u003c\/li\u003e\n\u003cli\u003e2034 Mini-banana plug, red\u003c\/li\u003e\n\u003cli\u003e2035 Mini-banana plug solderable turrent (two)\u003c\/li\u003e\n\u003cli\u003eEP1 Ag\/AgCl pellet (70 mm wire) 1 mm diam x 2.5 mm long\u003c\/li\u003e\n\u003cli\u003eM3301EH Electrode Holder, 14cm (two)\u003c\/li\u003e\n\u003cli\u003e5470 0.031-inch jack on 12-inch wire (package of 4)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eApplications \u003c\/h2\u003e\n\u003cp\u003eMutliple applications are available with a variety of options. Here you can see two setups.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eDIFFERENTIAL APPLICATION FOR METAL ELECTRODES \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eIn this setup, metal electrodes are used with a differential amplifier. In this setup, a DAM80 is shown, but you could easily substitute a DAM50 (with 5489), ISO-DAM8A (with 74040) or ISO-80.\u003c\/p\u003e\n\u003cp\u003e \u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0662\/7993\/1994\/files\/damsetup2_8a2961a4-1f39-49ef-ab00-60e275e65aeb.jpg?v=1765946604\" alt=\"Differential Application For Metal Electrodes\" width=\"496\" height=\"330\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0662\/7993\/1994\/files\/ISO-80-Differential-application_6864d541-4bcb-4b2a-9cd9-3a3ce4ee6307.jpg?v=1765946610\" alt=\"ISO-80 differential application setup\" width=\"85%\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0662\/7993\/1994\/files\/ISO-80-optional-differential-application_7a67ab31-386d-4b3a-a88c-a0a0f42ff0ac.jpg?v=1765946615\" alt=\"Differential application setup with ISO-80\" width=\"75%\"\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEXTRACELLULAR APPLICATIONS UTILIZING GLASS\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eFor rare instances when using extracellular amplifiers with glass, you could use the setup shown below. In this setup, a DAM80 is shown, but you could easily substitute an ISODAM8A (with 74040) or ISO-80. Likewise, this setup shows the 2505 handle (1\/4\" - 6.3mm), but if you have a smaller micromanipulator, you may need the 5444 handle (3\/16\" - 4.8mm). In this illustration, MEH7W-10 is used, but any glass-size MEH7W could be used. (MEH7W-10 is 1.0mm glass, MEH7W-12 is 1.2mm glass, MEH7W-15 is 1.5mm glass and MEH7W-20 is 2.0mm glass.) EP2 is used for grounding in the illustration.\u003c\/p\u003e\n\u003cp\u003eFor single-ended applications, however, a 2033 wire adapter on the black connector socket can be connected to the 3294 cable. The tip used depends on your specific needs. In the illustration, TIP1TW1 was suggested. NOTE that the glass is not shown in the illustration below. \u003cspan style=\"font-size: 12pt; line-height: 1.3em;\"\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cimg style=\"margin: 5px; width: 469px; height: 418px;\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0662\/7993\/1994\/files\/damsetup1_45eab984-e1ff-407c-b1cd-2933fc4572f4.jpg?v=1765946621\" alt=\"Extracellular Applications Utilizing Glass\" width=\"469\" height=\"418\"\u003e\u003c\/p\u003e\n\u003cp\u003e \u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0662\/7993\/1994\/files\/ISO-80-single-ended-application_4ec40597-4d80-4e2a-8b62-d2ca8874bcb8.jpg?v=1765946627\" alt=\"ISO-80 single ended application\" width=\"80%\"\u003e\u003c\/p\u003e\n\u003c!-- \/section:details --\u003e\n\n\u003c!-- section:resources --\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0662\/7993\/1994\/files\/ISO-80_IM.pdf\" target=\"_self\"\u003eISO-80 Manual\u003c\/a\u003e\u003c\/p\u003e\n\u003c!-- \/section:resources --\u003e\n\n\u003c!-- section:specifications --\u003e\n\u003ctable border=\"1\" cellspacing=\"0\" cellpadding=\"2\"\u003e\r\n\u003ctbody\u003e\r\n\u003ctr\u003e\r\n\u003ctd\u003eInput Resistance\u003c\/td\u003e\r\n\u003ctd\u003e10\u003csup\u003e11\u003c\/sup\u003eΩ, Common Mode and differential\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\r\n\u003ctd\u003eInput Leakage Current\u003c\/td\u003e\r\n\u003ctd\u003e50 pA, max.\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd\u003eAmplification\u003c\/td\u003e\r\n\u003ctd\u003ex10\u003csup\u003e2\u003c\/sup\u003e, x10\u003csup\u003e3\u003c\/sup\u003e, x10\u003csup\u003e4\u003c\/sup\u003e\n\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\r\n\u003ctd\u003eCommon Mode Rejection Ratio\u003c\/td\u003e\r\n\u003ctd\u003e100 dB typ. @ 50\/60 Hz\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd\u003eEquivalent Noise Signal Input\u003c\/td\u003e\r\n\u003ctd\u003e0.4 µV rms (0.1-100 Hz) 2.0 µV rms (1 Hz - 10 kHz)\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\r\n\u003ctd\u003eFilter Settings:Low frequency\u003c\/td\u003e\r\n\u003ctd\u003e5, 10, 100, 300 Hz\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd\u003eFilter Settings:High frequency\u003c\/td\u003e\r\n\u003ctd\u003e100 Hz, 1, 3, 10 kHz\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\r\n\u003ctd\u003eMax. Output Voltage Swing\u003c\/td\u003e\r\n\u003ctd\u003e±8 V\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd\u003eElectrode Impedance Range\u003c\/td\u003e\r\n\u003ctd\u003e100 kΩ - 10 MΩ @ 300Hz\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\r\n\u003ctd\u003eStimulation Current\u003c\/td\u003e\r\n\u003ctd\u003e0 to ±20 µA (constant current)\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd\u003eMaximum STIMULATION Voltage\u003c\/td\u003e\r\n\u003ctd\u003e±15 V\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\r\n\u003ctd\u003eMaximum Electrode Voltage\u003c\/td\u003e\r\n\u003ctd\u003e±40 V\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd\u003eDispla y\u003c\/td\u003e\r\n\u003ctd\u003e3.5-digit LCD\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\r\n\u003ctd\u003eBATTERY TEST\u003c\/td\u003e\r\n\u003ctd\u003eLow battery display\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd\u003ePower\u003c\/td\u003e\r\n\u003ctd\u003eTwo 9 V Ni-MH batteries \u0026amp; charger,supplied\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\r\n\u003ctd\u003eSHIPPING WEIGHT\u003c\/td\u003e\r\n\u003ctd\u003e4 lb. (1.8 kg)\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003c\/tbody\u003e\r\n\u003c\/table\u003e\n\u003c!-- \/section:specifications --\u003e","brand":"World Precision Instruments","offers":[{"title":"Default Title","offer_id":42272862208090,"sku":"ISO-80","price":3750.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/7993\/1994\/files\/iso-80_2_37987a43-ec63-417a-b2f5-da9b815b074a.jpg?v=1766398221"},{"product_id":"sys-dam50-dam50-extracellular-amplifier","title":"DAM50 Extracellular Amplifier","description":"\u003c!-- section:details --\u003e\n\u003cp\u003eSee the current \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0662\/7993\/1994\/files\/DAM_DS.pdf\"\u003eSpec Sheet\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003eSee what you need to\u003ca href=\"\/blog\/post\/wpi-s-low-noise-amplifiers-outperform-cheap-imitations\/\"\u003e know before you buy an amplifier\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eA family of very low noise battery-operated amplifiers\u003c\/h2\u003e\n\u003ch2\u003eFeatures\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eBattery powered to eliminate line noise\u003c\/li\u003e\n\u003cli\u003eHigh pass and low pass filtering\u003c\/li\u003e\n\u003cli\u003eSingle ended or differential operation\u003c\/li\u003e\n\u003cli\u003eDC\/AC amplification\u003c\/li\u003e\n\u003cli\u003eVariable output positioning\u003c\/li\u003e\n\u003cli\u003eConstructed of high quality components to ensure minimal intrinsic (shot) noise\u003c\/li\u003e\n\u003cli\u003ePortable\u003c\/li\u003e\n\u003cli\u003eRack mountable\u003c\/li\u003e\n\u003cli\u003eThe DAM50 package now includes the 300647 shielded metal electrode cable and one shielded modular cable.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eBenefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eVery low internal noise\u003c\/li\u003e\n\u003cli\u003eUltra quiet DC power supply ­— no AC required\u003c\/li\u003e\n\u003cli\u003eIntrinsic low susceptibility to ground loops\u003c\/li\u003e\n\u003cli\u003eSmall footprint\u003c\/li\u003e\n\u003cli\u003eCost-effective\u003c\/li\u003e\n\u003cli\u003eElectrostatic Discharge Protection!\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eApplications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAmplifying biopotentials from metal electrodes\u003c\/li\u003e\n\u003cli\u003eBrain slice field stimulation\u003c\/li\u003e\n\u003cli\u003eEAG (Electroantennogram)\u003c\/li\u003e\n\u003cli\u003eERG (Electroretinogram)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eReducing Noise with Differential Amplification\u003c\/h2\u003e\n\u003cp\u003eDifferential amplification is of great importance in bioelectric recording to reduce the ever present effect of noise interference from power line induction. A well designed differential amplifier will significantly diminish power line (mains) noise. It is most essential that the preparation be connected with an electrode to a good electrical ground as well as to the grounding wire of the DAM50 itself. This should have the effect of greatly reducing electrostatically induced potential. In addition to the preparation ground, two differential input connections must be made via appropriate electrodes applied to the recording site so as to optimally record a bioelectric potential difference.\u003c\/p\u003e\n\u003ch2\u003eFeature Comparison Chart\u003c\/h2\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr style=\"background-color: #0081c2;\"\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u003cspan style=\"color: #ffffff;\"\u003e\u003cstrong\u003eType\u003c\/strong\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u003cspan style=\"color: #ffffff;\"\u003e\u003cstrong\u003eDAM50\u003c\/strong\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u003cspan style=\"color: #ffffff;\"\u003e\u003cstrong\u003eDAM80\u003c\/strong\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #e4e4e4;\"\u003e\n\u003ctd\u003eInput Mode\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eAC\/DC\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eAC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eInput Configuration\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eDifferential\/Single Ended\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eDifferential\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #e4e4e4;\"\u003e\n\u003ctd\u003eGain Range\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e100-10,000 (AC)\u003cbr\u003e10-1,000 (DC)\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e100 - 10,000 (AC)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHigh\/Low Filters\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eYes\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eYes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #e4e4e4;\"\u003e\n\u003ctd\u003eOffset Position Control\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eYes\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eYes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCurrent Generator\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eNo\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eYes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #e4e4e4;\"\u003e\n\u003ctd\u003eRemote Active Headstage\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eNo\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eYes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOutput Connection\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eBNC\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e3.5 mm mini phone\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #e4e4e4;\"\u003e\n\u003ctd\u003eStandard Input Connection\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eunterminated wire\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eMini banana\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePower Supply\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e(2) 9V alkaline batteries\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e(2) 9V alkaline batteries\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003e      \u003c\/p\u003e\n\u003ch2\u003eDifferential Applications for Metal Electrodes\u003c\/h2\u003e\n\u003cp\u003eThe images below show two applications for metal electrodes.  \u003c\/p\u003e\n\u003cp\u003eIn this first example, a sealed RC1T Ag\/AgCl electrode pellet is wired to the amplifier cable. This also shows a differential configuration.\u003c\/p\u003e\n\u003cp\u003e\u003cimg height=\"500\" width=\"500\" alt=\"DAM50\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0662\/7993\/1994\/files\/DAM50_Aa01_cc0dd12a-941d-47e2-91dd-a76af6401480.jpg?v=1765947822\"\u003e\u003c\/p\u003e\n\u003cp\u003eThis second example shows an EP2 silver\/silver chloride electrode pellet connected to  the amplifier adaptor 5389. This shows a differential configuration. The EP2 is suitable for use in a mouse cranial application. To do so, it needs an extension wire 3294 to connect it to the 5389 adaptor.\u003c\/p\u003e\n\u003cp\u003e\u003cimg height=\"500\" width=\"500\" alt=\"Dam50\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0662\/7993\/1994\/files\/DAM50_Ba01_6829c3a7-86d8-49dc-af3e-7d0aa3ffb495.jpg?v=1765947828\"\u003e\u003c\/p\u003e\n\u003c!-- \/section:details --\u003e\n\n\u003c!-- section:resources --\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0662\/7993\/1994\/files\/dam50-im-082208.pdf\"\u003eDAM50 Instruction Manual\u003c\/a\u003e\u003c\/p\u003e\n\u003c!-- \/section:resources --\u003e\n\n\u003c!-- section:specifications --\u003e\n\u003ctable border=\"1\" cellspacing=\"0\" cellpadding=\"2\"\u003e\r\n\u003ctbody\u003e\r\n\u003ctr\u003e\r\n\u003ctd\u003eINPUT IMPEDANCE\u003c\/td\u003e\r\n\u003ctd\u003e10\u003csup\u003e12\u003c\/sup\u003e Ω, common mode and differential\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\r\n\u003ctd\u003eINPUT LEAKAGE CURRENT\u003c\/td\u003e\r\n\u003ctd\u003e50 pA (typical)\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd\u003eMAX. DC DIFFERENTIAL SIGNAL\u003c\/td\u003e\r\n\u003ctd\u003e±2.5 V (DAM 50)\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\r\n\u003ctd\u003eGAIN\u003c\/td\u003e\r\n\u003ctd\u003eAC: 100x, 1000x, 10000x, DC: 10x, 100x, 1000x (DAM50)\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd\u003eCOMMON MODE REJECTION RATIO\u003c\/td\u003e\r\n\u003ctd\u003e100dB @ 50\/60 Hz\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\r\n\u003ctd\u003eINPUT CAPACITANCE\u003c\/td\u003e\r\n\u003ctd\u003e20 pF\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd\u003eAC MODE NOISE\u003c\/td\u003e\r\n\u003ctd\u003e0.4 μV RMS (2uV p-p) 0.1-100 Hz\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\r\n\u003ctd\u003eAC MODE NOISE\u003c\/td\u003e\r\n\u003ctd\u003e2.6 μV RMS (10uV p-p) 1 Hz-10 kH\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd\u003eDC MODE NOISE (DAM50)\u003c\/td\u003e\r\n\u003ctd\u003e(DAM50) 7.5uV RMS (30uV p-p) 3-10 kHz\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\r\n\u003ctd\u003eBANDWIDTH FILTER SETTINGS:AC Mode\u003c\/td\u003e\r\n\u003ctd\u003eLow frequency, 0.1, 1, 10, 300 Hz\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd\u003eBANDWIDTH FILTER SETTINGS: DC Mode(DAM50)\u003c\/td\u003e\r\n\u003ctd\u003eHigh frequency, 0.1, 1, 3, 10 kHz\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\r\n\u003ctd\u003eOUTPUT CONNECTORS\u003c\/td\u003e\r\n\u003ctd\u003eBNC\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd\u003eOUTPUT VOLTAGE SWING\u003c\/td\u003e\r\n\u003ctd\u003e±8 V\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\r\n\u003ctd\u003eOUTPUT IMPEDANCE\u003c\/td\u003e\r\n\u003ctd\u003e470 Ω\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd\u003eBATTERY TEST\u003c\/td\u003e\r\n\u003ctd\u003eAudible tone\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\r\n\u003ctd\u003eCALIBRATOR SIGNAL\u003c\/td\u003e\r\n\u003ctd\u003e10 Hz square wave\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd\u003ePOSITION\u003c\/td\u003e\r\n\u003ctd\u003eApproximately 250 mV\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\r\n\u003ctd\u003eEXTERNAL COMMAND\u003c\/td\u003e\r\n\u003ctd\u003eInput Voltage ±10 V commands\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd\u003eAC or DC current waveform\u003c\/td\u003e\r\n\u003ctd\u003e±50μA max. amplitude @ 200 KΩ\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\r\n\u003ctd\u003eBATTERIES\u003c\/td\u003e\r\n\u003ctd\u003e2 x 9 V alkaline (included)\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr\u003e\r\n\u003ctd\u003eDIMENSIONS:DAM50\u003c\/td\u003e\r\n\u003ctd\u003e8 x 4 x 1.75 in. (20.3 x 10.2 x 4.4 cm)\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\r\n\u003ctd\u003eSHIPPING WEIGHT\u003c\/td\u003e\r\n\u003ctd\u003e3.5 lb. (1.6 kg)\u003c\/td\u003e\r\n\u003c\/tr\u003e\r\n\u003c\/tbody\u003e\r\n\u003c\/table\u003e\r\n\u003cp\u003eThe following bandwidth charts for the DAM50 show the response of the amplifier when various filters and gains are used. For larger images, click on the thumbnails below. \u003c\/p\u003e\r\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0662\/7993\/1994\/files\/dam50_graph005.jpg\"\u003e\u003cimg style=\"margin: 5px;\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0662\/7993\/1994\/files\/dam50_graph005sm.jpg\" alt=\"Bandwidth charts for the DAM50\" width=\"288\" height=\"182\"\u003e\u003c\/a\u003e\u003c\/p\u003e\r\n\u003cp\u003e\u003cem\u003eGAINS: This chart shows the standard 3dB frequency cutoff at \u003c\/em\u003e maximum filter band pass.\u003c\/p\u003e\r\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0662\/7993\/1994\/files\/dam50_graph004.jpg\"\u003e\u003cimg style=\"margin: 5px;\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0662\/7993\/1994\/files\/dam50_graph004sm.jpg\" alt=\"The standard 3dB frequency\" width=\"288\" height=\"178\"\u003e\u003c\/a\u003e\u003c\/p\u003e\r\n\u003cp\u003e\u003cem\u003eFILTERS: Various low pass and high pass filters were applied at the AC x1000 gain setting to show the bandwidth of and actual DAM50 amplifier. \u003c\/em\u003e\u003c\/p\u003e\n\u003c!-- \/section:specifications --\u003e\n\n\u003c!-- section:references --\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eKim, E. Y., \u0026amp; Virginia, W. (n.d.). Effect of Growth Hormone on Hippocampal Synaptic Function during Sleep Deprivation By.\u003c\/p\u003e\r\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003efull-text. (n.d.).\u003c\/p\u003e\r\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eDai, J., Brooks, D. I., \u0026amp; Sheinberg, D. L. (n.d.). Supplemental Information Optogenetic and Electrical Microstimulation Systematically Bias Visuospatial Choice in Primates.\u003c\/p\u003e\r\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eŠkorjanc, A., \u0026amp; Belušič, G. (n.d.). How We Teach: Classroom And Laboratory Research Projects Investigation of blood flow and the effect of vasoactive substances in cutaneous blood vessels of Xenopus laevis.\u003c\/p\u003e\r\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eLiu, Y., Wang, Y., Zhu, G., Sun, J., Bi, X., \u0026amp; Baudry, M. (2016). A calpain-2 selective inhibitor enhances learning \u0026amp;amp; memory by prolonging ERK activation. \u003ci\u003eNeuropharmacology\u003c\/i\u003e, \u003ci\u003e105\u003c\/i\u003e, 471–477. \u003ca href=\"http:\/\/doi.org\/10.1016\/j.neuropharm.2016.02.022\"\u003ehttp:\/\/doi.org\/10.1016\/j.neuropharm.2016.02.022\u003c\/a\u003e\u003c\/p\u003e\r\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eZtaou, S., Maurice, N., Camon, J., Guiraudie-Capraz, G., Kerkerian-Le Goff, L., Beurrier, C., … Amalric, M. (2016). Involvement of Striatal Cholinergic Interneurons and M1 and M4 Muscarinic Receptors in Motor Symptoms of Parkinson’s Disease. \u003ci\u003eJournal of Neuroscience\u003c\/i\u003e, \u003ci\u003e36\u003c\/i\u003e(35).\u003c\/p\u003e\r\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eKentish, S. S. J., Frisby, C. L., Kritas, S., Li, H., Hatzinikolas, G., O’Donnell, T. A., … Ahern, G. (2015). TRPV1 Channels and Gastric Vagal Afferent Signalling in Lean and High Fat Diet Induced Obese Mice. \u003ci\u003ePloS One\u003c\/i\u003e, \u003ci\u003e10\u003c\/i\u003e(8), e0135892. \u003ca href=\"http:\/\/doi.org\/10.1371\/journal.pone.0135892\"\u003ehttp:\/\/doi.org\/10.1371\/journal.pone.0135892\u003c\/a\u003e\u003c\/p\u003e\r\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eBlauvelt, D. G., Sato, T. F., Wienisch, M., \u0026amp; Murthy, V. N. (2013). Distinct spatiotemporal activity in principal neurons of the mouse olfactory bulb in anesthetized and awake states. \u003ci\u003eFrontiers in Neural Circuits\u003c\/i\u003e, \u003ci\u003e7\u003c\/i\u003e. \u003ca href=\"http:\/\/doi.org\/10.3389\/fncir.2013.00046\"\u003ehttp:\/\/doi.org\/10.3389\/fncir.2013.00046\u003c\/a\u003e\u003c\/p\u003e\r\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eBlaise, J. H. (2013). Long-term Potentiation of Perforant Pathway-dentate Gyrus Synapse in Freely Behaving Mice. \u003ci\u003eJournal of Visualized Experiments\u003c\/i\u003e, (81), e50642. \u003ca href=\"http:\/\/doi.org\/10.3791\/50642\"\u003ehttp:\/\/doi.org\/10.3791\/50642\u003c\/a\u003e\u003c\/p\u003e\r\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eWang, H., Siddharthan, V., Kesler, K. K., Hall, J. O., Motter, N. E., Julander, J. G., \u0026amp; Morrey, J. D. (2013). Fatal neurological respiratory insufficiency is common among viral encephalitides. \u003ci\u003eThe Journal of Infectious Diseases\u003c\/i\u003e, \u003ci\u003e208\u003c\/i\u003e(4), 573–83. \u003ca href=\"http:\/\/doi.org\/10.1093\/infdis\/jit186\"\u003ehttp:\/\/doi.org\/10.1093\/infdis\/jit186\u003c\/a\u003e\u003c\/p\u003e\r\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eZhang, Q.-X., Lu, R.-W., Curcio, C. A., Yao, X.-C., DC., H., SE., N., … PN, D. (2012). In Vivo Confocal Intrinsic Optical Signal Identification of Localized Retinal Dysfunction. \u003ci\u003eInvestigative Opthalmology \u0026amp; Visual Science\u003c\/i\u003e, \u003ci\u003e53\u003c\/i\u003e(13), 8139. \u003ca href=\"http:\/\/doi.org\/10.1167\/iovs.12-10732\"\u003ehttp:\/\/doi.org\/10.1167\/iovs.12-10732\u003c\/a\u003e\u003c\/p\u003e\r\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eBadsha, F., Kain, P., Prabhakar, S., Sundaram, S., Padinjat, R., Rodrigues, V., \u0026amp; Hasan, G. (2012). Mutants in Drosophila TRPC channels reduce olfactory sensitivity to carbon dioxide. \u003ci\u003ePloS One\u003c\/i\u003e, \u003ci\u003e7\u003c\/i\u003e(11), e49848. \u003ca href=\"http:\/\/doi.org\/10.1371\/journal.pone.0049848\"\u003ehttp:\/\/doi.org\/10.1371\/journal.pone.0049848\u003c\/a\u003e\u003c\/p\u003e\r\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eKonow, N., Azizi, E., \u0026amp; Roberts, T. J. (2012). Muscle power attenuation by tendon during energy dissipation. \u003ci\u003eProceedings. Biological Sciences \/ The Royal Society\u003c\/i\u003e, \u003ci\u003e279\u003c\/i\u003e(1731), 1108–13. \u003ca href=\"http:\/\/doi.org\/10.1098\/rspb.2011.1435\"\u003ehttp:\/\/doi.org\/10.1098\/rspb.2011.1435\u003c\/a\u003e\u003c\/p\u003e\r\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eChen, S., Mohajerani, M. H., Xie, Y., \u0026amp; Murphy, T. H. (2012). Optogenetic analysis of neuronal excitability during global ischemia reveals selective deficits in sensory processing following reperfusion in mouse cortex. \u003ci\u003eThe Journal of Neuroscience : The Official Journal of the Society for Neuroscience\u003c\/i\u003e, \u003ci\u003e32\u003c\/i\u003e(39), 13510–9. \u003ca href=\"http:\/\/doi.org\/10.1523\/JNEUROSCI.1439-12.2012\"\u003ehttp:\/\/doi.org\/10.1523\/JNEUROSCI.1439-12.2012\u003c\/a\u003e\u003c\/p\u003e\r\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eMorrey, J. D., Siddharthan, V., Wang, H., Hall, J. O., Motter, N. E., Skinner, R. D., \u0026amp; Skirpstunas, R. T. (2010). Neurological suppression of diaphragm electromyographs in hamsters infected with West Nile virus. \u003ci\u003eJournal of Neurovirology\u003c\/i\u003e, \u003ci\u003e16\u003c\/i\u003e(4), 318–329. \u003ca href=\"http:\/\/doi.org\/10.3109\/13550284.2010.501847\"\u003ehttp:\/\/doi.org\/10.3109\/13550284.2010.501847\u003c\/a\u003e\u003c\/p\u003e\r\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eBrundage, C. M., \u0026amp; Taylor, B. E. (2010). Neuroplasticity of the central hypercapnic ventilatory response: teratogen-induced impairment and subsequent recovery during development. \u003ci\u003eDevelopmental Neurobiology\u003c\/i\u003e, \u003ci\u003e70\u003c\/i\u003e(10), 726–35. \u003ca href=\"http:\/\/doi.org\/10.1002\/dneu.20806\"\u003ehttp:\/\/doi.org\/10.1002\/dneu.20806\u003c\/a\u003e\u003c\/p\u003e\r\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eKim, E., Grover, L. M., Bertolotti, D., \u0026amp; Green, T. L. (2010). Growth hormone rescues hippocampal synaptic function after sleep deprivation. \u003ci\u003eAmerican Journal of Physiology. Regulatory, Integrative and Comparative Physiology\u003c\/i\u003e, \u003ci\u003e298\u003c\/i\u003e(6), R1588-96. \u003ca href=\"http:\/\/doi.org\/10.1152\/ajpregu.00580.2009\"\u003ehttp:\/\/doi.org\/10.1152\/ajpregu.00580.2009\u003c\/a\u003e\u003c\/p\u003e\r\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eKavlie, R. G., Kernan, M. J., \u0026amp; Eberl, D. F. (2010). Hearing in Drosophila requires TilB, a conserved protein associated with ciliary motility. \u003ci\u003eGenetics\u003c\/i\u003e, \u003ci\u003e185\u003c\/i\u003e(1), 177–88. \u003ca href=\"http:\/\/doi.org\/10.1534\/genetics.110.114009\"\u003ehttp:\/\/doi.org\/10.1534\/genetics.110.114009\u003c\/a\u003e \u003c\/p\u003e\r\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eLenti, L., Domoki, F., Gáspár, T., Snipes, J. A., Bari, F., \u0026amp; Busija, D. W. (2009). N-Methyl- d -Aspartate Induces Cortical Hyperemia through Cortical Spreading Depression-Dependent and -Independent Mechanisms in Rats. \u003ci\u003eMicrocirculation\u003c\/i\u003e, \u003ci\u003e16\u003c\/i\u003e(7), 629–639. \u003ca href=\"http:\/\/doi.org\/10.1080\/10739680903131510\"\u003ehttp:\/\/doi.org\/10.1080\/10739680903131510\u003c\/a\u003e\u003c\/p\u003e\r\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eSu, C.-K., Ho, C.-M., Kuo, H.-H., Wen, Y.-C., \u0026amp; Chai, C.-Y. (2009). Sympathetic-correlated c-Fos expression in the neonatal rat spinal cord in vitro. \u003ci\u003eJournal of Biomedical Science\u003c\/i\u003e, \u003ci\u003e16\u003c\/i\u003e(1), 44. \u003ca href=\"http:\/\/doi.org\/10.1186\/1423-0127-16-44\"\u003ehttp:\/\/doi.org\/10.1186\/1423-0127-16-44\u003c\/a\u003e\u003c\/p\u003e\r\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eBrundage, C. M., \u0026amp; Taylor, B. E. (2009). Timing and duration of developmental nicotine exposure contribute to attenuation of the tadpole hypercapnic neuroventilatory response. \u003ci\u003eDevelopmental Neurobiology\u003c\/i\u003e, \u003ci\u003e69\u003c\/i\u003e(7), 451–61. \u003ca href=\"http:\/\/doi.org\/10.1002\/dneu.20720\"\u003ehttp:\/\/doi.org\/10.1002\/dneu.20720\u003c\/a\u003e\u003c\/p\u003e\r\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eOrem, N. R., Xia, L., \u0026amp; Dolph, P. J. (2006). An essential role for endocytosis of rhodopsin through interaction of visual arrestin with the AP-2 adaptor. \u003ci\u003eJournal of Cell Science\u003c\/i\u003e, \u003ci\u003e119\u003c\/i\u003e(Pt 15), 3141–8. \u003ca href=\"http:\/\/doi.org\/10.1242\/jcs.03052\"\u003ehttp:\/\/doi.org\/10.1242\/jcs.03052\u003c\/a\u003e\u003c\/p\u003e\r\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eMarkham, M. R., \u0026amp; Stoddard, P. K. (2005). Adrenocorticotropic hormone enhances the masculinity of an electric communication signal by modulating the waveform and timing of action potentials within individual cells. \u003ci\u003eThe Journal of Neuroscience : The Official Journal of the Society for Neuroscience\u003c\/i\u003e, \u003ci\u003e25\u003c\/i\u003e(38), 8746–54. \u003ca href=\"http:\/\/doi.org\/10.1523\/JNEUROSCI.2809-05.2005\"\u003ehttp:\/\/doi.org\/10.1523\/JNEUROSCI.2809-05.2005\u003c\/a\u003e\u003c\/p\u003e\r\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eCartford, M. C. (2004). Cerebellar norepinephrine modulates learning of delay classical eyeblink conditioning: Evidence for post-synaptic signaling via PKA. \u003ci\u003eLearning \u0026amp; Memory\u003c\/i\u003e, \u003ci\u003e11\u003c\/i\u003e(6), 732–737. \u003ca href=\"http:\/\/doi.org\/10.1101\/lm.83104\"\u003ehttp:\/\/doi.org\/10.1101\/lm.83104\u003c\/a\u003e\u003c\/p\u003e\r\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eJonker, D. M., Vermeij, D. A. C., Edelbroek, P. M., Voskuyl, R. A., Piotrovsky, V. K., \u0026amp; Danhof, M. (2003). Pharmacodynamic Analysis of the Interaction between Tiagabine and Midazolam with an Allosteric Model That Incorporates Signal Transduction. \u003ci\u003eEpilepsia\u003c\/i\u003e, \u003ci\u003e44\u003c\/i\u003e(3), 329–338. \u003ca href=\"http:\/\/doi.org\/10.1046\/j.1528-1157.2003.37802.x\"\u003ehttp:\/\/doi.org\/10.1046\/j.1528-1157.2003.37802.x\u003c\/a\u003e\u003c\/p\u003e\r\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003evan den Pol, A. N., Ghosh, P. K., Liu, R., Li, Y., Aghajanian, G. K., \u0026amp; Gao, X.-B. (2002). Hypocretin (orexin) enhances neuron activity and cell synchrony in developing mouse GFP-expressing locus coeruleus. \u003ci\u003eThe Journal of Physiology\u003c\/i\u003e, \u003ci\u003e541\u003c\/i\u003e(1), 169–185. \u003ca href=\"http:\/\/doi.org\/10.1113\/jphysiol.2002.017426\"\u003ehttp:\/\/doi.org\/10.1113\/jphysiol.2002.017426\u003c\/a\u003e\u003c\/p\u003e\r\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eRansom, C. B., Ransom, B. R., \u0026amp; Sontheimer, H. (2000). Activity-dependent extracellular K+ accumulation in rat optic nerve: the role of glial and axonal Na+ pumps. \u003ci\u003eThe Journal of Physiology\u003c\/i\u003e, \u003ci\u003e522 Pt 3\u003c\/i\u003e, 427–42. Retrieved from \u003ca href=\"http:\/\/www.pubmedcentral.nih.gov\/articlerender.fcgi?artid=2269766\u0026amp;tool=pmcentrez\u0026amp;rendertype=abstract\"\u003ehttp:\/\/www.pubmedcentral.nih.gov\/articlerender.fcgi?artid=2269766\u0026amp;tool=pmcentrez\u0026amp;rendertype=abstract\u003c\/a\u003e\u003c\/p\u003e\r\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eAlloway, P. G., \u0026amp; Dolph, P. J. (1999). A role for the light-dependent phosphorylation of visual arrestin. \u003ci\u003eProceedings of the National Academy of Sciences\u003c\/i\u003e, \u003ci\u003e96\u003c\/i\u003e(11), 6072–6077. \u003ca href=\"http:\/\/doi.org\/10.1073\/pnas.96.11.6072\"\u003ehttp:\/\/doi.org\/10.1073\/pnas.96.11.6072\u003c\/a\u003e\u003c\/p\u003e\r\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eLipchik, G. L., Holroyd, K. A., France, C. R., Kvaal, S. A., Segal, D., Cordingley, G. E., … McCool, H. R. (1996). Central and peripheral mechanisms in chronic tension-type headache. \u003ci\u003ePain\u003c\/i\u003e, \u003ci\u003e64\u003c\/i\u003e(3), 467–75. Retrieved from \u003ca href=\"http:\/\/www.pubmedcentral.nih.gov\/articlerender.fcgi?artid=2128054\u0026amp;tool=pmcentrez\u0026amp;rendertype=abstract\"\u003ehttp:\/\/www.pubmedcentral.nih.gov\/articlerender.fcgi?artid=2128054\u0026amp;tool=pmcentrez\u0026amp;rendertype=abstract\u003c\/a\u003e\u003c\/p\u003e\r\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eKnuckey, N. W., Palm, D., Primiano, M., Epstein, M. H., \u0026amp; Johanson, C. E. (1995). N-Acetylcysteine Enhances Hippocampal Neuronal Survival After Transient Forebrain Ischemia in Rats. \u003ci\u003eStroke\u003c\/i\u003e, \u003ci\u003e26\u003c\/i\u003e(2), 305–311. \u003ca href=\"http:\/\/doi.org\/10.1161\/01.STR.26.2.305\"\u003ehttp:\/\/doi.org\/10.1161\/01.STR.26.2.305\u003c\/a\u003e\u003c\/p\u003e\n\u003c!-- \/section:references --\u003e","brand":"World Precision Instruments","offers":[{"title":"Default Title","offer_id":42272907067482,"sku":"SYS-DAM50","price":2100.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/7993\/1994\/files\/dam50-cable_f63449e3-728b-4aa5-8ae4-b8de3c817ee7.png?v=1766399605"},{"product_id":"sys-dam80-extracellular-amplifier-with-active-probe","title":"Extracellular Amplifier with Active Probe","description":"\u003c!-- section:details --\u003e\n\u003ch2\u003eA family of very low noise battery-operated extracellular amplifiers\u003c\/h2\u003e\n\u003cp\u003eThe DAM80 Startup Kit includes: 2-CBL102, 5469, 2-13388, 3294, 2033, 2034, 2-2035\u003c\/p\u003e\n\u003cp\u003eSee the current \u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0662\/7993\/1994\/files\/DAM_DS.pdf\"\u003eSpec Sheet\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003eSee what you need to\u003ca href=\"\/blog\/post\/wpi-s-low-noise-amplifiers-outperform-cheap-imitations\/\"\u003e know before you buy an amplifier\u003c\/a\u003e.\u003c\/p\u003e\n\u003ch2\u003eFeatures\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eBattery powered to eliminate line noise\u003c\/li\u003e\n\u003cli\u003eHigh pass and low pass filtering\u003c\/li\u003e\n\u003cli\u003eSingle ended or differential operation\u003c\/li\u003e\n\u003cli\u003eAC amplification only\u003c\/li\u003e\n\u003cli\u003eIncludes low-noise headstage\u003c\/li\u003e\n\u003cli\u003eVariable output positioning\u003c\/li\u003e\n\u003cli\u003eConstructed of high quality components to ensure minimal intrinsic (shot) noise\u003c\/li\u003e\n\u003cli\u003ePortable\u003c\/li\u003e\n\u003cli\u003eRack mountable\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eBenefits\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eVery low internal noise\u003c\/li\u003e\n\u003cli\u003eUltra quiet DC power supply ­— no AC required\u003c\/li\u003e\n\u003cli\u003eIntrinsic low susceptibility to ground loops\u003c\/li\u003e\n\u003cli\u003eSmall footprint\u003c\/li\u003e\n\u003cli\u003eCost-effective\u003c\/li\u003e\n\u003cli\u003eElectrostatic Discharge Protection!\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003ch2\u003eApplications\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eAmplifying biopotentials from metal electrodes\u003c\/li\u003e\n\u003cli\u003eBrain slice field stimulation\u003c\/li\u003e\n\u003cli\u003eEAG (Electroantennogram)\u003c\/li\u003e\n\u003cli\u003eERG (Electroretinogram)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eWPI’s \u003cstrong\u003eDAM\u003c\/strong\u003e series amplifier’s are well known as a standard of the industry for extracellular potential amplification. These battery powered bio-amplifiers are designed with a compact chassis profile that enables the user to locate the unit closer to the preparation and thereby minimize long lead lengths which contribute to noise. Each amplifier is equipped with selectable high and low filters, and a position control to offset galvanic potentials which may develop during recording.\u003c\/p\u003e\n\u003cp\u003eThe startup kit (included) is shown in the image below.\u003c\/p\u003e\n\u003cp\u003e\u003cimg height=\"432\" width=\"576\" alt=\"DAM80 Startup Kit includes the pictured components.\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0662\/7993\/1994\/files\/dam80kit_992d4f69-2fd4-4886-8b14-9e75dd253c82.jpg?v=1765947842\" style=\"margin: 5px;\"\u003e\u003c\/p\u003e\n\u003ch2\u003eRemote Active Headstage\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eDAM80\u003c\/strong\u003e, an AC amplifier only, features a very low noise headstage probe which can be mounted in micromanipulators for up-close cortical recording, for extracellular recording from high impedance glass or metal microelectrodes. The unit also provides a gated current for tissue marking. Microelectrode holder \u003ca href=\"\/var-3814-microelectrode-holder-meh7w\"\u003e\u003cstrong\u003eMEH7W-XX\u003c\/strong\u003e\u003c\/a\u003e (sold separately) is recommended for glass microelectrodes.\u003c\/p\u003e\n\u003ch2\u003eCurrent Generation\u003c\/h2\u003e\n\u003cp\u003eThe DAM80 is perfect for gated or manual current generation for histological marking, iontophoresis or cell stimulation. It includes a very low noise remote active headstage that is useful for very high impedance amplification utilizing glass or metal electrodes.\u003c\/p\u003e\n\u003ch2\u003ePortability\u003c\/h2\u003e\n\u003cp\u003e\u003cstrong\u003eDAM\u003c\/strong\u003e series amplifiers can be used as standalone units on any tabletop, or use optional clamp-mounting hardware to locate them conveniently within the work area. Alternatively, a pair of amplifiers can be mounted into a standard equipment rack with a rack mount kit (#\u003cstrong\u003e3484\u003c\/strong\u003e). A variety of hook up accessories are available to configure your application. \u003c\/p\u003e\n\u003ch2\u003eFeature Comparison Chart\u003c\/h2\u003e\n\u003ctable\u003e\n\u003ctbody\u003e\n\u003ctr style=\"background-color: #0081c2;\"\u003e\n\u003ctd\u003e \u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u003cspan style=\"color: #ffffff;\"\u003e\u003cstrong\u003eDAM50\u003c\/strong\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e\u003cspan style=\"color: #ffffff;\"\u003e\u003cstrong\u003eDAM80\u003c\/strong\u003e\u003c\/span\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #e4e4e4;\"\u003e\n\u003ctd\u003eInput Mode\u003c\/td\u003e\n\u003ctd\u003eAC\/DC\u003c\/td\u003e\n\u003ctd\u003eAC\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eInput Configuration\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eDifferential\/Single Ended\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eDifferential\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #e4e4e4;\"\u003e\n\u003ctd\u003eGain Range\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e100-10,000 (AC)\u003cbr\u003e10-1,000 (DC)\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e100 - 10,000 (AC)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eHigh\/Low Filters\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eYes\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eYes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #e4e4e4;\"\u003e\n\u003ctd\u003eOffset Position Control\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eYes\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eYes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCurrent Generator\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eNo\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eYes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #e4e4e4;\"\u003e\n\u003ctd\u003eRemote Active Headstage\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eNo\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eYes\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOutput Connection\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eBNC\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e3.5 mm mini phone\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"background-color: #e4e4e4;\"\u003e\n\u003ctd\u003eStandard Input Connection\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eunterminated wire\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003eMini banana\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePower Supply\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e(2) 9V alkaline batteries\u003c\/td\u003e\n\u003ctd style=\"text-align: center;\"\u003e(2) 9V alkaline batteries\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cdiv class=\"contentcontainer\" id=\"appnotescontainer\"\u003e\n\u003cp\u003eMutliple applications are available with a variety of options. Here you can see two setups.\u003c\/p\u003e\n\u003ch2\u003eDifferential Applications for Metal Electrodes\u003c\/h2\u003e\n\u003cp\u003eIn this setup, metal electrodes are used with a differential amplifier. In this setup, a \u003ca href=\"\/sys-dam80-extracellular-amplifier-with-active-probe\"\u003e\u003cstrong\u003eDAM80\u003c\/strong\u003e \u003c\/a\u003eis shown, but you could easily substitute a \u003ca href=\"\/sys-dam50-dam50-extracellular-amplifier\"\u003e\u003cstrong\u003eDAM50\u003c\/strong\u003e \u003c\/a\u003e(with \u003ca href=\"\/5489-optional-probe-for-dam50\"\u003e\u003cstrong\u003e5489\u003c\/strong\u003e\u003c\/a\u003e), \u003cstrong\u003eISO-DAM8A\u003c\/strong\u003e (with \u003ca href=\"\/74040-iso-dam8a-active-headstage\"\u003e\u003cstrong\u003e74040\u003c\/strong\u003e\u003c\/a\u003e) or \u003ca href=\"\/iso-80-isolated-differential-amplifier-with-active-probe\"\u003e\u003cstrong\u003eISO-80\u003c\/strong\u003e\u003c\/a\u003e.\u003c\/p\u003e\n\u003cp\u003e\u003cimg height=\"330\" width=\"496\" alt=\"DIFFERENTIAL APPLICATION FOR METAL ELECTRODES\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0662\/7993\/1994\/files\/damsetup2_21a259c3-95dc-41ab-923f-28dc4772870e.jpg?v=1765947848\"\u003e\u003c\/p\u003e\n\u003ch2\u003eExtracellular Applications Utilizing Glass Microelectrodes\u003c\/h2\u003e\n\u003cp\u003eFor rare instances when using extracellular amplifiers with glass, you could use the setup shown below. In this setup, a DAM80 is shown, but you could easily substitute an \u003cstrong\u003eISO-DAM8A\u003c\/strong\u003e (with \u003ca href=\"\/74040-iso-dam8a-active-headstage\"\u003e\u003cstrong\u003e74040\u003c\/strong\u003e\u003c\/a\u003e) or \u003ca href=\"\/iso-80-isolated-differential-amplifier-with-active-probe\"\u003e\u003cstrong\u003eISO-80\u003c\/strong\u003e\u003c\/a\u003e. Likewise, this setup shows the \u003ca href=\"\/2505-electrode-handle-63-mm\"\u003e\u003cstrong\u003e2505\u003c\/strong\u003e \u003c\/a\u003ehandle (1\/4\" - 6.3mm), but if you have a smaller micromanipulator, you may need the \u003ca href=\"\/5444-electrode-handle-48-mm\"\u003e\u003cstrong\u003e5444\u003c\/strong\u003e \u003c\/a\u003ehandle (3\/16\" - 4.8mm). In this illustration, \u003ca rel=\"noopener\" href=\"\/var-3814-microelectrode-holder-meh7w\" target=\"_blank\"\u003e\u003cstrong\u003eMEH7W-10\u003c\/strong\u003e \u003c\/a\u003eis used, but any glass-size \u003ca rel=\"noopener\" href=\"\/var-3814-microelectrode-holder-meh7w\" target=\"_blank\"\u003e\u003cstrong\u003eMEH7W\u003c\/strong\u003e \u003c\/a\u003ecould be used. (\u003ca rel=\"noopener\" href=\"\/var-3814-microelectrode-holder-meh7w\" target=\"_blank\"\u003e\u003cstrong\u003eMEH7W-10\u003c\/strong\u003e \u003c\/a\u003eis 1.0mm glass, \u003ca rel=\"noopener\" href=\"\/var-3814-microelectrode-holder-meh7w\" target=\"_blank\"\u003e\u003cstrong\u003eMEH7W-12\u003c\/strong\u003e \u003c\/a\u003eis 1.2mm glass, \u003ca rel=\"noopener\" href=\"\/var-3814-microelectrode-holder-meh7w\" target=\"_blank\"\u003e\u003cstrong\u003eMEH7W-15\u003c\/strong\u003e \u003c\/a\u003eis 1.5mm glass and \u003ca href=\"\/var-3814-microelectrode-holder-meh7w\"\u003e\u003cstrong\u003eMEH7W-20\u003c\/strong\u003e \u003c\/a\u003eis 2.0mm glass.) \u003ca href=\"\/var-2739-ag-agcl-electrode\"\u003e\u003cstrong\u003eEP2\u003c\/strong\u003e \u003c\/a\u003eis used for grounding in the illustration.\u003c\/p\u003e\n\u003cp\u003eFor single-ended applications, however, a \u003ca href=\"\/2033-black-insulated-mini-banana-plug\"\u003e\u003cstrong\u003e2033\u003c\/strong\u003e\u003c\/a\u003e wire adapter on the black connector socket can be connected to the \u003ca href=\"\/3294-ground-wire-for-dam80-probe\"\u003e\u003cstrong\u003e3294\u003c\/strong\u003e\u003c\/a\u003e cable. The tip used depends on your specific needs. In the illustration, \u003ca href=\"\/var-3564-pre-pulled-glass-pipettes\"\u003e\u003cstrong\u003eTIP1TW1\u003c\/strong\u003e \u003c\/a\u003ewas suggested. NOTE that the glass is not shown in the illustration below.\u003c\/p\u003e\n\u003cp\u003e\u003cimg height=\"418\" width=\"469\" alt=\"EXTRACELLULAR APPLICATIONS UTILIZING GLASS\" src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0662\/7993\/1994\/files\/damsetup1_81b0fb71-843c-40ff-a980-343604d34af6.jpg?v=1765947854\" style=\"margin: 5px;\"\u003e\u003c\/p\u003e\n\u003cp\u003e   \u003c\/p\u003e\n\u003c\/div\u003e\n\u003c!-- \/section:details --\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003c!-- section:resources --\u003e\n\u003cp\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0662\/7993\/1994\/files\/DAM80_IMs.pdf\" target=\"_self\"\u003eDAM80 Instruction Manual\u003c\/a\u003e\u003c\/p\u003e\n\u003c!-- \/section:resources --\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003c!-- section:specifications --\u003e\n\u003ctable cellpadding=\"2\" cellspacing=\"0\" border=\"1\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eINPUT IMPEDANCE\u003c\/td\u003e\n\u003ctd\u003e10\u003csup\u003e12 \u003c\/sup\u003eΩ, common mode and differential\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\n\u003ctd\u003eINPUT LEAKAGE CURRENT\u003c\/td\u003e\n\u003ctd\u003e50 pA (typical)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCOMMON MODE REJECTION RATIO\u003c\/td\u003e\n\u003ctd\u003e100 dB @ 50\/60 Hz\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\n\u003ctd\u003eINPUT CAPACITANCE\u003c\/td\u003e\n\u003ctd\u003e20 pF\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAC MODE NOISE\u003c\/td\u003e\n\u003ctd\u003e0.4 µV RMS (2uV p-p) 0.1-100 Hz\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\n\u003ctd\u003eAC MODE NOISE\u003c\/td\u003e\n\u003ctd\u003e2.6 µV RMS (10uV p-p) 1Hz-10 kH\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eBANDWIDTH FILTER SETTINGS, AC Mode\u003c\/td\u003e\n\u003ctd\u003eLow frequency, 0.1, 1, 10, 300 Hz\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\n\u003ctd\u003eBANDWIDTH FILTER SETTINGS: AC Mode(DAM80)\u003c\/td\u003e\n\u003ctd\u003eHigh frequency, 0.1, 1, 3, 10 kHz\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOUTPUT CONNECTORS\u003c\/td\u003e\n\u003ctd\u003e3.5 mm MiniPhone connector on DAM80\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\n\u003ctd\u003eOUTPUT VOLTAGE SWING\u003c\/td\u003e\n\u003ctd\u003e±8V\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOUTPUT IMPEDANCE\u003c\/td\u003e\n\u003ctd\u003e470 Ω\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\n\u003ctd\u003eBATTERY TEST\u003c\/td\u003e\n\u003ctd\u003eAudible tone\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCALIBRATOR SIGNAL\u003c\/td\u003e\n\u003ctd\u003e10 Hz square wave\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\n\u003ctd\u003ePOSITION\u003c\/td\u003e\n\u003ctd\u003eApproximately 250 mV\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eCURRENT SOURCE:DAM80: DC Generator\u003c\/td\u003e\n\u003ctd\u003e0 to ±50 µA, variable\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\n\u003ctd\u003eEXTERNAL COMMAND\u003c\/td\u003e\n\u003ctd\u003eInput Voltage ±10 V commands\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eAC or DC current waveform\u003c\/td\u003e\n\u003ctd\u003e±50 µA max. amplitude @ 200 Ω\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\n\u003ctd\u003eBATTERIES\u003c\/td\u003e\n\u003ctd\u003e2 x 9 V alkaline (included)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDIMENSIONS:DAM80\u003c\/td\u003e\n\u003ctd\u003e7 x 4 x 1.75 in. (17.8 x 10.2 x 4.4 cm)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr bgcolor=\"#e6e6e6\"\u003e\n\u003ctd\u003eSHIPPING WEIGHT\u003c\/td\u003e\n\u003ctd\u003e3.5 lb. (1.6 kg)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c!-- \/section:specifications --\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003c!-- section:references --\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eDonnelly, W. T., Bartlett, D., \u0026amp; Leiter, J. C. (2016). Serotonin in the solitary tract nucleus shortens the laryngeal chemoreflex in anaesthetized neonatal rats. \u003ci\u003eExperimental Physiology\u003c\/i\u003e, \u003ci\u003e101\u003c\/i\u003e(7), 946–961. \u003ca href=\"http:\/\/doi.org\/10.1113\/EP085716\"\u003ehttp:\/\/doi.org\/10.1113\/EP085716\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eFeng, B., Joyce, S. C., \u0026amp; Gebhart, G. F. (2016). Optogenetic activation of mechanically insensitive afferents in mouse colorectum reveals chemosensitivity. \u003ci\u003eAmerican Journal of Physiology - Gastrointestinal and Liver Physiology\u003c\/i\u003e, \u003ci\u003e310\u003c\/i\u003e(10).\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eKaldenbach, F., Bleckmann, H., \u0026amp; Kohl, T. (2016). Responses of infrared-sensitive tectal units of the pit viper Crotalus atrox to moving objects. \u003ci\u003eJournal of Comparative Physiology A\u003c\/i\u003e, \u003ci\u003e202\u003c\/i\u003e(6), 389–398. \u003ca href=\"http:\/\/doi.org\/10.1007\/s00359-016-1076-1\"\u003ehttp:\/\/doi.org\/10.1007\/s00359-016-1076-1\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eMustafina, A. N., Koroleva, K. S., Giniatullin, R. A., \u0026amp; Sitdikova, G. F. (2016). Acid Sensitive Ion Channels as Target of Hydrogen Sulfide in Rat Trigeminal Neurons. \u003ci\u003eBioNanoScience\u003c\/i\u003e, 1–3. \u003ca href=\"http:\/\/doi.org\/10.1007\/s12668-016-0237-6\"\u003ehttp:\/\/doi.org\/10.1007\/s12668-016-0237-6\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eOrton, L. D., Papasavvas, C. A., \u0026amp; Rees, A. (2016). Commissural Gain Control Enhances the Midbrain Representation of Sound Location. \u003ci\u003eThe Journal of Neuroscience : The Official Journal of the Society for Neuroscience\u003c\/i\u003e, \u003ci\u003e36\u003c\/i\u003e(16), 4470–81. \u003ca href=\"http:\/\/doi.org\/10.1523\/JNEUROSCI.3012-15.2016\"\u003ehttp:\/\/doi.org\/10.1523\/JNEUROSCI.3012-15.2016\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003ePalanca-Castan, N., Laumen, G., Reed, D., \u0026amp; Köppl, C. (2016). The Binaural Interaction Component in Barn Owl (Tyto alba) Presents few Differences to Mammalian Data. \u003ci\u003eJournal of the Association for Research in Otolaryngology\u003c\/i\u003e, 1–13. \u003ca href=\"http:\/\/doi.org\/10.1007\/s10162-016-0583-7\"\u003ehttp:\/\/doi.org\/10.1007\/s10162-016-0583-7\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eFeng, B., \u0026amp; Gebhart, G. F. (2015). \u0026amp;lt;em\u0026amp;gt;In vitro\u0026amp;lt;\/em\u0026amp;gt; Functional Characterization of Mouse Colorectal Afferent Endings. \u003ci\u003eJournal of Visualized Experiments\u003c\/i\u003e, (95), e52310–e52310. \u003ca href=\"http:\/\/doi.org\/10.3791\/52310\"\u003ehttp:\/\/doi.org\/10.3791\/52310\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eGholami, M., Moradpour, F., Semnanian, S., Naghdi, N., \u0026amp; Fathollahi, Y. (2015). Chronic sodium salicylate administration enhances population spike long-term potentiation following a combination of theta frequency primed-burst stimulation and the transient application of pentylenetetrazol in rat CA1 hippocampal neurons. \u003ci\u003eEuropean Journal of Pharmacology\u003c\/i\u003e, \u003ci\u003e767\u003c\/i\u003e, 165–174. \u003ca href=\"http:\/\/doi.org\/10.1016\/j.ejphar.2015.10.021\"\u003ehttp:\/\/doi.org\/10.1016\/j.ejphar.2015.10.021\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eKim, Y.-J., \u0026amp; Kang, T.-C. (2015). The role of TRPC6 in seizure susceptibility and seizure-related neuronal damage in the rat dentate gyrus. \u003ci\u003eNeuroscience\u003c\/i\u003e, \u003ci\u003e307\u003c\/i\u003e, 215–230. \u003ca href=\"http:\/\/doi.org\/10.1016\/j.neuroscience.2015.08.054\"\u003ehttp:\/\/doi.org\/10.1016\/j.neuroscience.2015.08.054\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eKulthinee, S., Wyss, J. M., \u0026amp; Roysommuti, S. (2015). Taurine supplementation prevents the adverse effect of high sugar intake on arterial pressure control after cardiac ischemia\/reperfusion in female rats. \u003ci\u003eAdvances in Experimental Medicine and Biology\u003c\/i\u003e, \u003ci\u003e803\u003c\/i\u003e, 597–611. \u003ca href=\"http:\/\/doi.org\/10.1007\/978-3-319-15126-7_48\"\u003ehttp:\/\/doi.org\/10.1007\/978-3-319-15126-7_48\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eBouabid, S., Delaville, C., De Deurwaerdère, P., Lakhdar-Ghazal, N., \u0026amp; Benazzouz, A. (2014). Manganese-Induced Atypical Parkinsonism Is Associated with Altered Basal Ganglia Activity and Changes in Tissue Levels of Monoamines in the Rat. \u003ci\u003ePLoS ONE\u003c\/i\u003e, \u003ci\u003e9\u003c\/i\u003e(6), e98952. \u003ca href=\"http:\/\/doi.org\/10.1371\/journal.pone.0098952\"\u003ehttp:\/\/doi.org\/10.1371\/journal.pone.0098952\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eGal, R., Kaiser, M., Haspel, G., Libersat, F., Fouad, K., Libersat, F., … Yack, J. (2014). Sensory Arsenal on the Stinger of the Parasitoid Jewel Wasp and Its Possible Role in Identifying Cockroach Brains. \u003ci\u003ePLoS ONE\u003c\/i\u003e, \u003ci\u003e9\u003c\/i\u003e(2), e89683. \u003ca href=\"http:\/\/doi.org\/10.1371\/journal.pone.0089683\"\u003ehttp:\/\/doi.org\/10.1371\/journal.pone.0089683\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eHuo, B.-X., Smith, J. B., \u0026amp; Drew, P. J. (2014). Neurovascular coupling and decoupling in the cortex during voluntary locomotion. \u003ci\u003eThe Journal of Neuroscience : The Official Journal of the Society for Neuroscience\u003c\/i\u003e, \u003ci\u003e34\u003c\/i\u003e(33), 10975–81. \u003ca href=\"http:\/\/doi.org\/10.1523\/JNEUROSCI.1369-14.2014\"\u003ehttp:\/\/doi.org\/10.1523\/JNEUROSCI.1369-14.2014\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eHermann, P. M., Park, D., Beaulieu, E., \u0026amp; Wildering, W. C. (2013). Evidence for inflammation-mediated memory dysfunction in gastropods: putative PLA2 and COX inhibitors abolish long-term memory failure induced by systemic immune challenges. \u003ci\u003eBMC Neuroscience\u003c\/i\u003e, \u003ci\u003e14\u003c\/i\u003e(1), 83. \u003ca href=\"http:\/\/doi.org\/10.1186\/1471-2202-14-83\"\u003ehttp:\/\/doi.org\/10.1186\/1471-2202-14-83\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eKam, T.-I., Song, S., Gwon, Y., Park, H., Yan, J.-J., Im, I., … Jung, Y.-K. (2013). FcγRIIb mediates amyloid-β neurotoxicity and memory impairment in Alzheimer’s disease. \u003ci\u003eThe Journal of Clinical Investigation\u003c\/i\u003e, \u003ci\u003e123\u003c\/i\u003e(7), 2791–802. \u003ca href=\"http:\/\/doi.org\/10.1172\/JCI66827\"\u003ehttp:\/\/doi.org\/10.1172\/JCI66827\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003ePark, H.-J., Bonmassar, G., Kaltenbach, J. A., Machado, A. G., Manzoor, N. F., \u0026amp; Gale, J. T. (2013). Activation of the central nervous system induced by micro-magnetic stimulation. \u003ci\u003eNature Communications\u003c\/i\u003e, \u003ci\u003e4\u003c\/i\u003e, 2463. \u003ca href=\"http:\/\/doi.org\/10.1038\/ncomms3463\"\u003ehttp:\/\/doi.org\/10.1038\/ncomms3463\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eSanchez-Jimenez, A., Torets, C., \u0026amp; Panetsos, F. (2013). Complementary processing of haptic information by slowly and rapidly adapting neurons in the trigeminothalamic pathway. Electrophysiology, mathematical modeling and simulations of vibrissae-related neurons. \u003ci\u003eFrontiers in Cellular Neuroscience\u003c\/i\u003e, \u003ci\u003e7\u003c\/i\u003e, 79. \u003ca href=\"http:\/\/doi.org\/10.3389\/fncel.2013.00079\"\u003ehttp:\/\/doi.org\/10.3389\/fncel.2013.00079\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eSotoyama, H., Namba, H., Chiken, S., Nambu, A., \u0026amp; Nawa, H. (2013). Exposure to the cytokine EGF leads to abnormal hyperactivity of pallidal GABA neurons: implications for schizophrenia and its modeling. \u003ci\u003eJournal of Neurochemistry\u003c\/i\u003e, \u003ci\u003e126\u003c\/i\u003e(4), 518–28. \u003ca href=\"http:\/\/doi.org\/10.1111\/jnc.12223\"\u003ehttp:\/\/doi.org\/10.1111\/jnc.12223\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eJirakulsomchok, D., Napawachirahat, S., Kunbootsri, N., Suttitum, T., Wannanon, P., Wyss, J. M., \u0026amp; Roysommuti, S. (2012). Impaired renal response to portal infusion of hypertonic saline in adriamycin-treated rats. \u003ci\u003eClinical and Experimental Pharmacology and Physiology\u003c\/i\u003e, \u003ci\u003e39\u003c\/i\u003e(7), 636–641. \u003ca href=\"http:\/\/doi.org\/10.1111\/j.1440-1681.2012.05722.x\"\u003ehttp:\/\/doi.org\/10.1111\/j.1440-1681.2012.05722.x\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eKato, Y. X., Furukawa, S., Samejima, K., Hironaka, N., \u0026amp; Kashino, M. (2012). Photosensitive-polyimide based method for fabricating various neural electrode architectures. \u003ci\u003eFrontiers in Neuroengineering\u003c\/i\u003e, \u003ci\u003e5\u003c\/i\u003e. \u003ca href=\"http:\/\/doi.org\/10.3389\/fneng.2012.00011\"\u003ehttp:\/\/doi.org\/10.3389\/fneng.2012.00011\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eOhnami, S., Kato, A., Ogawa, K., Shinohara, S., Ono, H., \u0026amp; Tanabe, M. (2012). Effects of milnacipran, a 5-HT and noradrenaline reuptake inhibitor, on C-fibre-evoked field potentials in spinal long-term potentiation and neuropathic pain. \u003ci\u003eBritish Journal of Pharmacology\u003c\/i\u003e, \u003ci\u003e167\u003c\/i\u003e(3), 537–47. \u003ca href=\"http:\/\/doi.org\/10.1111\/j.1476-5381.2012.02007.x\"\u003ehttp:\/\/doi.org\/10.1111\/j.1476-5381.2012.02007.x\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eRazy-Krajka, F., Brown, E. R., Horie, T., Callebert, J., Sasakura, Y., Joly, J.-S., … Vernier, P. (2012). Monoaminergic modulation of photoreception in ascidian: evidence for a proto-hypothalamo-retinal territory. \u003ci\u003eBMC Biology\u003c\/i\u003e, \u003ci\u003e10\u003c\/i\u003e(1), 45. \u003ca href=\"http:\/\/doi.org\/10.1186\/1741-7007-10-45\"\u003ehttp:\/\/doi.org\/10.1186\/1741-7007-10-45\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eHu, W., Bi, Y., Zhang, K., Meng, F., \u0026amp; Zhang, J. (2011). High-frequency electrical stimulation in the nucleus accumbens of morphine-treated rats suppresses neuronal firing in reward-related brain regions. \u003ci\u003eMedical Science Monitor : International Medical Journal of Experimental and Clinical Research\u003c\/i\u003e, \u003ci\u003e17\u003c\/i\u003e(6), BR153-60. Retrieved from \u003ca href=\"https:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3539543\" rel=\"noopener\" target=\"_blank\"\u003ehttps:\/\/pmc.ncbi.nlm.nih.gov\/articles\/PMC3539543\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eKim, J.-E., \u0026amp; Kang, T.-C. (2011). The P2X7 receptor–pannexin-1 complex decreases muscarinic acetylcholine receptor–mediated seizure susceptibility in mice. \u003ci\u003eJournal of Clinical Investigation\u003c\/i\u003e, \u003ci\u003e121\u003c\/i\u003e(5), 2037–2047. \u003ca href=\"http:\/\/doi.org\/10.1172\/JCI44818\"\u003ehttp:\/\/doi.org\/10.1172\/JCI44818\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eKim, J.-E., \u0026amp; Kang, T.-C. (2011). The P2X7 receptor-pannexin-1 complex decreases muscarinic acetylcholine receptor-mediated seizure susceptibility in mice. \u003ci\u003eThe Journal of Clinical Investigation\u003c\/i\u003e, \u003ci\u003e121\u003c\/i\u003e(5), 2037–47. \u003ca href=\"http:\/\/doi.org\/10.1172\/JCI44818\"\u003ehttp:\/\/doi.org\/10.1172\/JCI44818\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eSchwarz, D., Bloom, D., Castro, R., Pagán, O. R., \u0026amp; Jiménez-Rivera, C. A. (2011). Parthenolide Blocks Cocaine’s Effect on Spontaneous Firing Activity of Dopaminergic Neurons in the Ventral Tegmental Area. \u003ci\u003eCurrent Neuropharmacology\u003c\/i\u003e, \u003ci\u003e9\u003c\/i\u003e(1), 17–20. \u003ca href=\"http:\/\/doi.org\/10.2174\/157015911795017010\"\u003ehttp:\/\/doi.org\/10.2174\/157015911795017010\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eBedi, S. S., Yang, Q., Crook, R. J., Du, J., Wu, Z., Fishman, H. M., … Walters, E. T. (2010). Chronic Spontaneous Activity Generated in the Somata of Primary Nociceptors Is Associated with Pain-Related Behavior after Spinal Cord Injury. \u003ci\u003eJournal of Neuroscience\u003c\/i\u003e, \u003ci\u003e30\u003c\/i\u003e(44), 14870–14882. \u003ca href=\"http:\/\/doi.org\/10.1523\/JNEUROSCI.2428-10.2010\"\u003ehttp:\/\/doi.org\/10.1523\/JNEUROSCI.2428-10.2010\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eGwak, Y. S., Unabia, G. C., \u0026amp; Hulsebosch, C. E. (2009). Activation of p-38alpha MAPK contributes to neuronal hyperexcitability in caudal regions remote from spinal cord injury. \u003ci\u003eExperimental Neurology\u003c\/i\u003e, \u003ci\u003e220\u003c\/i\u003e(1), 154–61. \u003ca href=\"http:\/\/doi.org\/10.1016\/j.expneurol.2009.08.012\"\u003ehttp:\/\/doi.org\/10.1016\/j.expneurol.2009.08.012\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eGwak, Y. S., Crown, E. D., Unabia, G. C., \u0026amp; Hulsebosch, C. E. (2008). Propentofylline attenuates allodynia, glial activation and modulates GABAergic tone after spinal cord injury in the rat. \u003ci\u003ePain\u003c\/i\u003e, \u003ci\u003e138\u003c\/i\u003e(2), 410–22. \u003ca href=\"http:\/\/doi.org\/10.1016\/j.pain.2008.01.021\"\u003ehttp:\/\/doi.org\/10.1016\/j.pain.2008.01.021\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eGreger, B., Kateb, B., Gruen, P., \u0026amp; Patterson, P. H. (2007). A chronically implantable, hybrid cannula–electrode device for assessing the effects of molecules on electrophysiological signals in freely behaving animals. \u003ci\u003eJournal of Neuroscience Methods\u003c\/i\u003e, \u003ci\u003e163\u003c\/i\u003e(2), 321–325. \u003ca href=\"http:\/\/doi.org\/10.1016\/j.jneumeth.2007.03.017\"\u003ehttp:\/\/doi.org\/10.1016\/j.jneumeth.2007.03.017\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eZhao, P., Waxman, S. G., \u0026amp; Hains, B. C. (2006). Sodium channel expression in the ventral posterolateral nucleus of the thalamus after peripheral nerve injury. \u003ci\u003eMolecular Pain\u003c\/i\u003e, \u003ci\u003e2\u003c\/i\u003e, 27. \u003ca href=\"http:\/\/doi.org\/10.1186\/1744-8069-2-27\"\u003ehttp:\/\/doi.org\/10.1186\/1744-8069-2-27\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eCharles, C. J., Jardine, D. L., Nicholls, M. G., \u0026amp; Richards, A. M. (2005). Adrenomedullin increases cardiac sympathetic nerve activity in normal conscious sheep. \u003ci\u003eThe Journal of Endocrinology\u003c\/i\u003e, \u003ci\u003e187\u003c\/i\u003e(2), 275–81. \u003ca href=\"http:\/\/doi.org\/10.1677\/joe.1.06337\"\u003ehttp:\/\/doi.org\/10.1677\/joe.1.06337\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eKaminski, R. M., Marini, H., Kim, W.-J., \u0026amp; Rogawski, M. A. (2005). Anticonvulsant Activity of Androsterone and Etiocholanolone. \u003ci\u003eEpilepsia\u003c\/i\u003e, \u003ci\u003e46\u003c\/i\u003e(6), 819–827. \u003ca href=\"http:\/\/doi.org\/10.1111\/j.1528-1167.2005.00705.x\"\u003ehttp:\/\/doi.org\/10.1111\/j.1528-1167.2005.00705.x\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eLi, X., Conklin, D., Pan, H.-L., \u0026amp; Eisenach, J. C. (2003). Allosteric adenosine receptor modulation reduces hypersensitivity following peripheral inflammation by a central mechanism. \u003ci\u003eThe Journal of Pharmacology and Experimental Therapeutics\u003c\/i\u003e, \u003ci\u003e305\u003c\/i\u003e(3), 950–5. \u003ca href=\"http:\/\/doi.org\/10.1124\/jpet.102.047951\"\u003ehttp:\/\/doi.org\/10.1124\/jpet.102.047951\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eMasino, S. A. (2003). Quantitative comparison between functional imaging and single-unit spiking in rat somatosensory cortex. \u003ci\u003eJournal of Neurophysiology\u003c\/i\u003e, \u003ci\u003e89\u003c\/i\u003e(3), 1702–12. \u003ca href=\"http:\/\/doi.org\/10.1152\/jn.00860.2002\"\u003ehttp:\/\/doi.org\/10.1152\/jn.00860.2002\u003c\/a\u003e\u003c\/p\u003e\n\u003cp style=\"margin-left: 24pt; text-indent: -24.0pt;\"\u003eWichmann, T., Kliem, M. A., \u0026amp; DeLong, M. R. (2001). Antiparkinsonian and behavioral effects of inactivation of the substantia nigra pars reticulata in hemiparkinsonian primates. \u003ci\u003eExperimental Neurology\u003c\/i\u003e, \u003ci\u003e167\u003c\/i\u003e(2), 410–24. \u003ca href=\"http:\/\/doi.org\/10.1006\/exnr.2000.7572\"\u003ehttp:\/\/doi.org\/10.1006\/exnr.2000.7572\u003c\/a\u003e\u003c\/p\u003e\n\u003c!-- \/section:references --\u003e","brand":"World Precision Instruments","offers":[{"title":"Default Title","offer_id":42272907264090,"sku":"SYS-DAM80","price":3400.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0662\/7993\/1994\/files\/dam80-angle_f93695dc-3aa8-43df-9023-a37909d3ab92.jpg?v=1766399620"}],"url":"https:\/\/wpiinc.com\/collections\/electrophysiology.oembed","provider":"World Precision Instruments","version":"1.0","type":"link"}